Treating Depression Often Lies in a Gray Zone

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From The Washington Post: Doctors often turn first to antidepressants when treating patients with depression. However, the evidence shows that alternative treatments such as therapy and exercise are just as effective.

“A number of recent studies highlight the uncertainty involved with these treatment decisions. Researchers have dedicated considerable effort to studying the relative effectiveness between psychotherapies and antidepressants, frequently without finding much difference. For instance, a study published in 2012 reviewed data from more than 100 prior trials and included more than 10,000 patients; although psychotherapies and antidepressants each worked better than placebo in blinded trials at reducing depressive symptoms, neither of these treatments was more effective than the other. Furthermore, psychotherapies and antidepressants did no better overall than alternative therapies such as exercise.”

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