After taking the psychedelic drug ayahuasca, Martha Sneyd went into an extended altered state diagnosed as psychotic. Her terrifying ordeal ignited a spiritual initiation that eventually brought gifts of awakening, insight, and compassion. How did Martha emerge from her ecstatic journey through a mythic, archetypal world to become an advocate and teacher? What lessons can we learn about the dangers — and potentials — of psychedelics and of altered states of consciousness labeled “madness”? Today she is a mental health case worker in the UK National Health Service, co-director of an interdisciplinary research team, and voice for more humane and spiritual treatments for madness.