Suicidal Thoughts and Behavior With Antidepressant Treatment: A Reanalysis

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In 2004 and 2006, the FDA concluded that SSRI antidepressants increased the risk of suicidal ideation in children and adolescents. However, in this month's...

Lawsuit Filed for Alleged Zoloft-Related Birth Defects

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Lawyers in St. Louis have filed a lawsuit against Pfizer that alleges 18 children were born with birth defects caused by the antidepressant Zoloft...

Eli Lilly To Freeze Base Pay in 2012

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Citing financial pressure from the loss of its patent on Zyprexa, Eli Lilly announced that it will freeze base pay for most of its...

First Personal Injury Lawsuit Over Risperdal Starts in New Jersey

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Gary Skala's claim that 14 years of Risperdal caused his diabetes went to trial in New Jersey yesterday in the first personal injury lawsuit...

Bribery Alleged in Largest Antidepressant Study Ever Conducted

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A 2011 whistleblower complaint that was unsealed on January 20 of this year alleges that Forest Pharmaceuticals bribed a principle investigator of the STAR*D...

Assessing Increased Mortality Risks of Antipsychotics and Mood Stabilizers in Dementia

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An article in January's American Journal of Psychiatry weighs the relative risk of mortality associated with various antipsychotics and mood stabilizers used in the treatment of...

Medications May Add to Mortality Rate in Schizophrenia

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Dutch researchers write in the Journal of Clinical Psychopharmacology that, in a prospective study of 7415 persons with diagnoses of schizophrenia, use of a first-generation...

Antidepressants Increase Suicide Risk in Children and Adolescents

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In a meta-analysis of studies of 6039 individuals, researchers in the UK determined that, consistent with previous meta-analysses, antidepressants increased "suicide-related outcomes."  Read more    ...

Discontinuing Psychotropics Reduces Falls in Elderly

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Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

Antipsychotics Increase Retrovirus Activity in Humans

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Endogenous retroviruses, remnants of ancient infections that have become part of the human genome, have been associated with the development of schizophrenia. But researchers...

Pfizer Files to Consolidate Birth Defect Lawsuitsd

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With at least 59 lawsuits pending over birth defects allegedly caused by Zoloft, Pfizer moves to consolidate litigation near its headquarters in New York. Read...

J&J Earnings Down 89%

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The Wall Street Journal reports that Johnson & Johnson's fourth-quarter earnings fell 89% following settlements for misrepresenting the risks and benefits of Risperdal, its...

Alarm About Antipsychotics as Sleep Aids

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Canadian sleep researchers, writing in The Lancet, warn that weight gain, lipid and glucose dysregulation, restless leg syndrome, sleep-walking and eating while asleep, and...

Elevated Diabetes in Children Treated With Antipsychotics, Antidepressants

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Researchers at the University of Massachusetts found that children are more than twice as likely to develop diabetes when treated with antidepressants, and more...

J&J Settles Texas Medicaid Lawsuit for $158 Million

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Johnson & Johnson has agreed to settle Texas' lawsuit for the company's fraudulent marketing of Risperdal. The is the first time J&J has settled...

Texas Lawsuit Against J&J Underway

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Texas' lawsuit against Johnson & Johnson for its off-label marketing of Risperdal, which the state alleges involved fraudulent claims about the drug's safety and...

J & J to Pay More Than $1 Billion For Wrongful Marketing of Risperdal

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In order to resolve a civil investigation into the marketing of Risperdal for unapproved uses, Johnson & Johnson will pay more than $1 billion...

Antipsychotic Drugs and the Risk of Hyperglycemia in Older Adults Without Diabetes: A Population-Based...

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  Objective: To determine whether current antipsychotic use among older persons without diabetes is associated with a higher risk of hospital visits for hyperglycemia, as...

Antidepressants/Depression

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  A. The Natural Course of Depression Prior to the widespread use of antidepressants, the National Institute of Mental Health told the public that people regularly...

Mad In America’s Chapters

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Preface The World Health Organization has repeatedly found that people diagnosed with schizophrenia in the U.S. and other developed countries fare much worse than schizophrenia...

Antipsychotics and Chronic Illness

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A. The Chronicity Problem Becomes Apparent (1960s-1979s) It seems paradoxical that drugs that ameliorate acute psychotic symptoms over the short term will increase the likelihood...

Polypharmacy/Bipolar illness

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  A. Bipolar Illness Before the Psychopharmacology Era Prior to 1955, bipolar illness was a rare disorder. There were only 12,750 people  hospitalized with that disorder...

Outcomes in the Era of Atypical Antipsychotics

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Once second-generation antipsychotic drugs came on the market (which are known as “atypicals”), there were claims by psychiatric researchers that they would lead to...

ï»żA Research Timeline for Antipsychotic Drugs

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1883     Phenothiazines developed as synthetic dyes 1934     USDA develops phenothiazines as insecticides 1938     Phenothiazines used to kill swine parasites 1949  ...

ï»żA Rorschach Test for Psych Drugs

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On October 23, the New York Times ran a very nice feature story about a Los Angeles woman, Keris Myrick, who, even though she...