Tag: bias in medical research

Discussing informed consent, risk/benefit ratios, and the many sources of bias in clinical trials for drugs, in order to help the layperson better understand the research.

Virtually every single placebo-controlled drug trial in psychiatry is flawed, systematic reviews of trials are also flawed, and guidelines are flawed. Even the drug approval process is flawed.

From The Conversation: The Canadian Medical Association Journal (CMAJ) has just published a new guideline for the management of hepatitis C — a disease that...

John Ioannidis claims that the idea of evidence based medicine has been “hijacked to serve agendas different from what it was originally aimed for,” in a newly published critical essay in the Journal of Clinical Epidemiology. Ioannidis frames the essay as a continuation of a conversation with David Sackett, widely considered the founder of evidence based medicine.