Wednesday, February 1, 2023

Tag: mental disorder

Despite “Flurry of Interest,” Ketamine Remains Unproven For Depression

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In 2014, then National Institute of Mental Health (NIMH) director, Thomas Insel, speculated that ketamine “might be the most important breakthrough in antidepressant treatment in decades.” A recent review of the research suggests that while ketamine may produce a rapid short-term improvement in depression, the effect is short-lived and the potential for addiction and dependence warrants considerable caution.

Large-Scale Study Reveals Arbitrariness of DSM Depression Diagnosis

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A new study on the depression symptoms of over three-thousand patients challenges the criteria used for diagnosing major depression with the latest Diagnostic and Statistical Manual (DSM-5). Current diagnostic systems are based on an assumption that the symptoms of depression point to a common underlying “illness," but research suggests that this framework may be outdated and oversimplified.

Massive Number of Antidepressant Meta-Analyses Biased By Industry

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A massive number of meta-analyses of antidepressant clinical trials have financial conflicts of interest and are unduly influenced by pharmaceutical companies, according to a review to be published in an upcoming issue of the Journal of Clinical Epidemiology. Researchers also found that meta-analyses with industry ties almost never report any negative findings in their abstracts.

John Oliver on Mental Health

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On his weekly HBO show, Last Week Tonight, host John Oliver argues that the tendency to discuss mental health in the wake of a mass shooting is "deeply misleading."