There are a vast number of studies that document the diverse range of side effects caused by antipsychotic drugs. These adverse effects include brain damage, tardive dyskinesia, Parkinsonian symptoms, akathisia, cognitive impairment, and metabolic disorders. Mad in America documents these negative effects; see Psychrights for PDFs of many of these studies.
On the fact that continual use of antipsychotics leads to early death, see the following:
Over a 10-year period, 39 out of 88 patient on antipsychotic drugs died. Reduced survival was associated with the administration of two or more neuroleptics at the same time, and time since withdrawal of antipsychotics (patients maintained on antipsychotics became burdened with chronic physical illness, so much so that it replaced the "psychiatric disorder as the primary focus of medical care.") The final pathway to early death was global medical decline and death from respiratory illness.
This study concluded that “risk for death in schizophrenia was doubled on a background of enduring engagement in psychiatric care with increasing provision of community-based services and introduction of second-generation antipsychotics.”