The Functional Neurology of Guilt in Depression


The University of Manchester in England, along with the D’Or Insitute in Rio de Janeiro, Brazil, have found that differences in activity in the cingulate cortex that are associated with guilt are present in subjects with major depression. Results are online in the Archives of General Psychiatry.

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People With Depression Respond To Guilt Differently: Study


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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected].



    Neurology will always send their patients to a psychiatrist.
    It won’t do you any good to ‘prove’ that a horse kicked you and killed half your brain.
    The resulting behaviours will be taken over by psychiatry with the same drugs, the same labels.
    It is all quite pathetic really, to even use the term “science”.
    The labels and drugs are still the problem. Created with no knowledge on what millions of neurons and synapses they disturb, to the detriment of the patient.
    To allow wanna be science loose with the brains of their relatives is the insanity that prevails.
    There is no pride in saying you are a scientist. It proves one can be disciplined to stay in school and be dumb enough to subscribe to absolutes without evidence, because eventually ALL investigations resulting in unknowns, or partial knowns, are still blessed with diagnosis.

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      • I have had a few ER docs tell me “psychiatry is a science”, verbatim.
        I have no arguments for them, it would be a waste of time.
        I simply say “interesting”
        I can’t even think of medicine/neurology as science, especially since they relied
        on psychiatry to support their lack of science, or simply to get rid of repeat patients aka the chronic illnesses.
        There is nothing more annoying to a doc than dealing with chronic illness and no better way to get rid of them than to leap to words like “depression”.

        I see studies on chronic illnesses where they studied normal subjects and those with a chronic illness and noticed facial differences. The chronic ill had more negative expression.
        Who wouda thought?
        Dying patients are depressed I hear.
        It is absolutely disgusting how dying has become a MI.
        We can’t leave this world without some labels.
        Most docs die at home.

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