Pfizer is in the final stages of settling 660 lawsuits filed between 2009 and 2012 by people who complained of of psychological problems, including suicides or suicide attempts. Presiding judge Inge Johnson said evidence showed Pfizer knew Chantix could cause neuropsychiatric injuries, but designed studies to exclude those with prior conditions that made them vulnerable, and with statistical significance cutoffs just above the point at which adverse reactions would be seen.
Of further interest:
Pfizer Resolves 700 Suits In Chantix Depression MDL (Law 360)
Pfizer, Merck, J&J all close books on some lawsuits (Fierce Pharma)