Meta-analysis: Medication-resistant Psychosis Responds to CBT

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University of British Columbia researchers conducted a meta-analysis that found positive effects from giving cognitive behavioral therapy to outpatients with medication-resistant psychosis. Publishing in Psychiatric Services, the researchers examined 16 published articles describing 12 randomized controlled trials involving 639 individuals. They found “overall beneficial effects of CBT” for positive symptoms and general symptoms.

“For patients who continue to exhibit symptoms of psychosis despite adequate trials of medication, CBT for psychosis can confer beneficial effects above and beyond the effects of medication,” they concluded.

Cognitive-Behavioral Therapy for Medication-Resistant Psychosis: A Meta-Analytic Review (Burns, Amy M. N. et al. Psychiatric Services 2014; doi: 10.1176/appi.ps.201300213)

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