Quotations From the Genetics âGraveyardâ: Nearly Half a Century of False Positive Gene Discovery...
In a 1992 essay, British psychiatric genetic researcher Michael Owen wondered whether schizophrenia molecular genetic research would become the âgraveyard of molecular geneticists.â1 Owen predicted that if major schizophrenia genes existed, they would be found within five years of that date. He was optimistic, believing that âtalk of graveyards is premature.â2 Owen now believes that genes for schizophrenia and other disorders have been found, and was subsequently knighted for his work. Despite massively improved technology, however, decades of molecular genetic gene finding attempts have failed to provide consistently replicated evidence of specific genes that play a role in causing the major psychiatric disorders.
Psychiatryâs Poor Image: Reflecting on Psychiatristsâ âApologiasâ
Those of us who critique psychiatry were recently treated to an interesting phenomenonâthe publicly available part of the January 2015 issue of Acta Psychiatrica Scandinavica, which contains multiple articles devoted to the question of psychiatryâs âpoor imageâ â how to understand it, how to assess it, what to do about it. The release of this issue is hardly the first occasion where articles have appeared in which psychiatrists have speculated on outsidersâ negative image of the profession. Indeed, more and more, we are seeing such articles together with other evidence that the professionals are concerned. This article probes the collection in question for themes, positions, and framing.
ECT for Agitation and Aggression in Dementia
The International Journal of Geriatric Psychiatry published an article titled Safety and utility of acute electroconvulsive therapy for agitation and aggression in dementia, which concludes "Electroconvulsive therapy may be a safe treatment option to reduce symptoms of agitation and aggression in patients with dementia whose behaviors are refractory to medication management." But the participants were not a random selection of people taking the drugs in question. Rather, they were individuals selected because of aggressive behavior, most of whom had been taking some or all of these drugs on admission. So it is a distinct possibility that the aggression was a drug effect for many, or even most, of the study participants.
Resolution for the New Year: Lay Down the Burden of Proof
It falls upon us survivors to prove that we were damaged, and that we arenât malingerers or attention hounds or âmentally illââ if we have any energy amidst the maelstrom to plead our case. Because if we donât, we risk having our narratives rewritten by othersâ âgood intentions,â misinformed though they may be by the mainstream narrative. People get weird and pushy about this stuff, both because suffering is ugly and because our truth threatens their worldview.
Trapped
Back in 1983, I put myself in a mental ward. I desperately wanted help with my eating disorder, but no one took these types of problems seriously back then. The ward was rather nice, so I returned many times. Nothing good ever came of it, but I always hoped this time, it will do some magic. Every time I left, I'd realize my eating problems hadn't been solved at all.
Do You Think It’s Real? Responding to Alternate Realities
Everyone has beliefs that seem too bizarre, illogical, or fantastic to someone else to accept. Religious views, paranormal interpretations, political convictions, interpersonal conflicts â all can put us in a category where other people consider what we think to be incomprehensible. We've learned to co-exist with different beliefs as one of our most cherished values of tolerance in a multicultural society. That lesson can be key for encountering the different realities that in situations where someone is being called psychotic, delusional, schizophrenic or mentally ill. Respect and support may stretch our thinking, but can be vital to recovery.
Depression: Itâs Not Your Serotonin
What if I told you that, in 6 decades of research, the serotonin (or norepinephrine, or dopamine) theory of depression and anxiety - the claim that âDepression is a serious medical condition that may be due to a chemical imbalance, and Zoloft works to correct this imbalanceâ - has not achieved scientific credibility? Youâd want some supporting arguments for this shocking claim. So, here you go:
Biology and Genetics are Irrelevant Once True Causes are Recognized
The psychiatric genetics literature contains few references to specific environmental factors that cause psychiatric disorders, and while researchers acknowledge a role for these factors, they usually claim that environmental causes are mysterious or unknown. As a leading group of psychiatric genetic researchers recently put it, while claiming that schizophrenia âhas a substantial genetic contribution,â the âunderlying causes and pathogenesis of the disorder remains unknown.â But research suggests otherwise.
Rethinking Cost Containment in Publicly Funded Psychiatric Drug Budgets
Given my experience as a state level administrator several years ago, I have continued an interest in the way which public expenditures for mental health reflect a variety of interests â usually in an attempt to limit expenditures from the state coffers. One of the areas of greatest concern to state legislators each session is the cost of participating in the Medicaid program. A significant portion of state mental health budgets, especially for community mental health programs, is in this pot of money. And psychiatric drugs are a major expense in state Medicaid program. As I will point out, however, there are major advocacy groups who want to expand, not limit access to these drugs.
Nitrous Oxide for Depression and Other Hazards of Modern Psychiatry
This week, MIA featured a news item regarding a recent âproof of conceptâ study conducted at Washington University of St. Louis to investigate whether nitrous oxide, commonly known as laughing gas, was effective in reducing symptoms of depression. Why is this a problem?
Rainbows and Unicorns
Happiness is the absence of sufferingâŠ
Iâve since come to realize this aphorism applies also to the suffering I endured while on and coming off psychiatric drugs: When that particular suffering â physical, emotional, neurological, psychological, sociological â had ended or mostly so, I was happy again. It was as simple as that. I was so relieved to no longer be in a state of terror, agony, and agitation, and to not have my life controlled by others (i.e., the âdoctorsâ), that I felt happy â not just by comparison against being miserable, but because it was so enlivening, liberating, and hope-instilling to not be miserable.
My Mysterious Son
In the autumn of 1996, my son was seventeen when he told me one day on the way home from school: âI donât know whatâs happening, I canât find my old self again.â Heâd had a seemingly marvelous summer staying with family in Mexico, fishing and learning to surf. Heâd achieved nearly a full scholarship for his junior year at a Boston private school. However, one teacher had observed that, in class, he âsometimes seems to be out of touch and unable to focus his mind.â
What Does Santa Think About ADHD Drugs?
NEWS FLASH (North Pole, Somewherereallycold)-- According to sources at the North Pole, Santa is not happy about the growing use of ADHD drugs. As you know, long ago, he had made his list and checked it twice. But with more than 4.5 million kids in the USA alone doing ADHD drugs every day, he has had to redo his list infinitum.
What Would Better Treatment for Those with Psychosis Look Like?
In the post on the debate between Allen Frances and Bob Whitaker, Frances argues that we should all advocate better treatment for those with psychosis. I think that we all might embrace the goal of better, more empathic treatment. However, we will differ on what âbetter treatmentâ might entail. I would argue that a return to the state hospital systems of the 1960s would not constitute better treatment.
Psychiatry and the Problem of the Medical Model – Part 1
The mental health industry has a lot to answer. The psychologization of everyday life has eroded the range of human experience seen as normal, disempowered people to manage their own life challenges, professionalized helping relationships and undermined the already decaying support structures through which people found meaning and connection, stigmatized people through psychiatric labeling, led to iatrogenic misery from harmful treatments and traumatized already vulnerable individuals through excessively coercive practices.
Thereâs More to Sleep than Shuts the Eye:Â Waking Up to All that Sleep Does...
Every day for most people, something mysterious begins to take shape that still defies scientists in these times. Although the primary reasons for most basic bodily functions, such as eating and moving, have been known for centuries â sleep, or also known as slumbering or snoozing or napping or crashing â still remains an enigma in many ways
The Truth About Antidepressant Research: An Invitation to Dialogue
The Finnish Psychological Association held a meeting in Helsinki on 1 Sept 2014 titled âMental Health and Medicalization.â I spoke at the meeting and four days later I sent a letter to another speaker, psychiatrist Erkki IsometsĂ€. Professor IsometsĂ€ replied: âI will respond to it in detail within a few days..." As "Open Dialogue" is essential in science, I have published my letter to IsometsĂ€ here as well as on my own website, although I didnât succeed in starting a dialogue.
Enough is Enough Series: An Hallucinogen for Depression? Psychiatry is Testing Ketamine (âSpecial...
The article âSpecial K, a Hallucinogen, Raises Hopes and Concerns as a Treatment for Depression,â by Andrew Pollack in the New York Times, December 9, 2014, tells how far afield my field, psychiatry, has really gone - that it is even a consideration to use an hallucinogen for the treatment of depression.
Assessing the Cost of Psychiatric Drugs to the Elderly and Disabled Citizens of the...
ProPublica is well known for creating interesting data bases that allow anyone hooked up to a computer to see by name whether a physician is accepting Big Pharma payments â from dinners to speaking engagements to consulting services. What may be lesser known is that occasionally ProPublica will publish other data that when carefully mined can reveal even more about the use of psychiatric drugs especially when there is a public funding source available.
Sick‘s Wild Ride – From Treatment to TEDMED
Earlier this year, I was invited to speak at TEDMED 2014 and John Kazanjian and I worked hard to come up with a 13-ish minute version of my play Sick. The video of the talk/performance got released today on TEDMED.com and YouTube. Itâs been a wild ride sharing the big play with small audiences around the country these last couple of years, and I am excited and humbled by the potential audience this abbreviated version can have online. I hope you have a chance to watch it.
Healing is in Our Stories
I have spent a lot of time talking to politicians, media members and those working in the mental health system about the failings of the current method of viewing and treating emotional distress. I have come to the conversations armed with stats and outcomes about the bio-medical paradigm. I have found that the people I speak with do not doubt the facts conveyed. They seem to agree that the current state of affairs is not good. The difference is that I think the tragic outcomes demonstrate the failure of the current system. The folks I talk to tend to think things are so bad because âmental illness is just that serious.â
Dr. Datta â Still Repackaging Psychiatry
On December 1, Mad in America published an article titled When Homosexuality Came Out (of the DSM). The author is Vivek Datta, MD, MPH, a British physician. The article was also published the same day on Dr. Datta's blog site, Medicine and Society. The article focuses on the removal of homosexuality from the DSM, which occurred in 1973. Dr. Datta discusses this issue and various related themes, and he draws some conclusions that, in my opinion, are unwarranted and misleading.
Finding Human Life on Earth
Through the ISPS listserve, I read a blog this morning written by Thomas Insel, director of the NIMH. The way he described people I daily meet in work and in my own life created a rising pulse, so I decided to find out some more about his thoughts and practice. I am not saying that what I read on his blog is unknown to me, but still it made me wonder how on earth is it possible to invest so much money - and resources - in research which is so distant from practice, and so far away from humanistic and holistic ideas and theories.
Studies of Reared-Apart (Separated) Twins: Facts and Fallacies
Twin studies supply the most frequently cited evidence in favor of important genetic influences on human behavioral differences. In an extremely small yet influential handful of studies, twin pairs were said to have been reared apart in different families. Twin researchers and others view this occurrence as the ultimate test of the relative influences of nature (genes) and nurture (environment). According to this view all behavioral resemblance between reared-apart MZ twin pairs (known as âMZAâ pairs) must be the result of their 100% genetic similarity, because such pairs share no environmental similarity. But, far from being separated at birth and reared apart in randomly selected homes representing the full range of potential behavior-influencing environments, and meeting each other for the first time when studied, most MZA pairs were only partially reared apart, and grew up in similar cultural and socioeconomic environments at the same time.
Coercion in Care
To this day I do not know how I found my way back. I think it mightâve had something to do with willpower, as I was NOT going to lose myself. I was NOT going to end up like those people who were living indefinitely in the hospitalâthose âchronic schizophrenicsâ, as they say. I was going to find my way back, back to myself.