The Children Lead

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How is it that we allow the agendas of others to occupy our childrens’ minds? Is it possible that a stranger can know our child better than we do? Is there anything a baby needs to learn that can’t be taught by being held in a parent’s arms? Because my children’s eyes and ears and thoughts are on me every day, they are key players in my ongoing efforts to live a right life. I count on their eyes and ears and thoughts to shore me up during times of temptation. They always lead me home.

The Road to Perdition

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The recent research scandals out of the University of Minnesota’s Department of Psychiatry may be alarming, but they are not new. Back in the 1990s, when the university was working its way towards a crippling probation by the National Institutes of Health (for yet another episode of misconduct (this time in the Department of Surgery), the Department of Psychiatry hosted two spectacular cases of research wrongdoing, both of which resulted in faculty members being disqualified from conducting research by the FDA.

The Denial of Pain and Mortality: Or, the Art of Self-Prescribing and the Philosopher’s...

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“Don’t look at me! Save yourself!” Andrew* was a 25 year old with an imposing build that was mollified only by his despair and terror. Andrew was losing his mind. I didn’t have to see Andrew and I somewhat wish I never did. I had received a call late at night from Andrew’s nurse. “You gotta give him something man, I mean, he’s freaking out and I feel really bad.”

How 7 Historic Figures Overcame Depression without Doctors

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While Sylvia Plath and Ernest Hemingway received extensive medical treatment for depression but tragically committed suicide, other famously depressed people—including Abraham Lincoln, William James, Georgia O’Keeffe, Sigmund Freud, William Tecumseh Sherman, Franz Kafka, and the Buddha—have taken different paths. Did those luminaries who took alternative paths and recovered really have the symptoms of major depression, and did their antidotes really work?

Were Research Subjects Mistreated in the CATIE Study?

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The suicide of Dan Markingson at the University of Minnesota has brought notoriety to the CAFÉ study and its site investigators, Stephen Olson and Charles Schulz. But the “corrective action” recently issued by the Minnesota Board of Social Work against the CAFÉ study coordinator, Jean Kenney, has raised another disturbing question.

Fact-Checking the General Counsel in the Markingson Case

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Ever since critics began asking questions about the death of Dan Markinson in a clinical trial at the University of Minnesota, the General Counsel for the university, Mark Rotenberg, has responded with a uniform message: the case has already been investigated many times, and no wrongdoing has ever been found. That's how Rotenberg responded to my article about the case in Mother Jones, and that's how he responded last week to the news that the Board of Social Work had issued a “corrective action” to the study coordinator for the clinical trial in which Markingson died.

The University of Minnesota was not Involved? Some Further Thoughts on the “Corrective...

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The suicide of Dan Markingson at the University of Minnesota has brought notoriety to the CAFÉ study and its site investigators, Stephen Olson and Charles Schulz. But the “corrective action” recently issued by the Minnesota Board of Social Work against the CAFÉ study coordinator, Jean Kenney, has raised another disturbing question.

“Do We Have to Wait Until He Kills Himself or Someone Else Before Anyone...

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In the "agreement for corrective action" against CAFE study coordinator Jean Kenney last week, the Board of Social Work cited Kenney's failure to respond to "alarming voicemail messages" from family members of Dan Markingson. Presumably, the Board is referring to a message left by his mother, Mary Weiss, which warned, "Do we have to wait until he kills himself or someone else before anyone else does anything?" The failure of Kenney and Stephen Olson to take the warnings of Mary Weiss seriously has been one of the most disturbing aspects of this case. In a deposition for the lawsuit filed by Weiss, Kenney was questioned about her response. Here is an excerpt. (The initial questions come from Gale Pearson, an attorney for Mary Weiss.)

“I Was Just Following Orders”: a Seroquel Suicide, a Study Coordinator, and a “Corrective...

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Out here in Minnesota, where the snow is gently falling, many of us are hunched over our computers, puzzling over a document just posted by the state Board of Social Work. It concerns the death of Dan Markingson (or as the document calls him, “Client #1”). Markingson, of course, was a young man under a commitment order who was coerced into a profitable Seroquel marketing study at the University of Minnesota over the objections of his mother, and whose condition spiraled downward until he committed suicide.

Dr. Friedman Criticizes the Overuse of the Atypical Antipsychotics

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Just being “safe and effective” is not a strong endorsement, and it lacks any justification for the exorbitant amounts of money that have been paid for these medications. Their commercial success was due to the fact that they were advertised as “better” not just safe. Texas and 36 other states have now realize that they were misled about second-generation antipsychotics being better, and they are recouping their money.

Discussing The Meaning of Antipsychotics

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Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...

Benzos Raise Dementia Risk 50%

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A 15-year prospective study, in the British Medical Journal this week, of 1063 subjects by researchers from the University of Bordeaux and Harvard University...

Schizophrenia-Immune System “Link” Opens the Door to Research

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"In order to expose people to dangerous treatments - and immunosuppresive drugs do carry risks - you need serious evidence to suggest those drugs...

Death of a Child Linked to Onset of Psychosis

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Using data from the National Comorbidity Survey, researchers found that individuals with a psychotic disorder who had lost a child had a significantly later...

Addiction, Biological Psychiatry and the Disease Model (Part 1)

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Both addiction and “mental illness” are far more prevalent where there is poverty, patriarchy, and other forms of mental and physical violence; all this creates fertile ground for various forms of trauma experiences on a daily basis. Addiction and extreme states of psychological distress will never be fully eradicated, or even humanely treated on a broad scale, until the material conditions from which they have emerged are transformed in a truly revolutionary way.

Neuroleptic Drugs and Violence

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Neuroleptic Drugs and Violence by Catherine Clarke SRN, SCM, MSSCH, MBChA. and Jan Evans MCSP. Grad Dip Phys.

Low Prevalence of Obesity and Metabolic Syndrome in Never-Treated Chronic Schizophrenia

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Research from India indicates that "schizophrenia in the absence of antipsychotic drug treatment is not a factor contributing to high prevalence of metabolic abnormalities." Abstract...

Cortisol Levels Increased in Youth at Risk for Psychosis

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Researchers from Columbia University and the Institute of Neurosciences in Barcelona assessed cortisol levels in 33 patients at clinical high risk of psychosis. Cortisol...

Type of Treatment for Depression is Less Important than Engagement

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An international team of researchers (including Irving Kirsch) found in a review "of 62 pivotal antidepressant trials consisting of data from 13,802 depressed patients"...

Happiness and First-Episode Schizophrenia

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Canadian researchers find that 31 people with first-episode schizophrenia diagnoses were as happy as 29 controls, according to a self-reported questionnaire measuring happiness, life...

“Grief is Good News for Pharmaceutical Companies”

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The U.K.'s Guardian writes today that "the proposal by the American Psychiatric Association to create a new illness – prolonged grief disorder – and...

“A Drop of Sunshine”

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Film by Apama Sanyal "Schizophrenia. It may be one word, but it immediately conjures up multiple connotations - mad, incurable, violent, suicidal, chemical imbalances, crazy,...

Social Phobia is Not a Neuropsychological Deficit

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Researchers at the University of Central Florida, saying "there are relatively few existing studies examining neuropsychological functioning in social phobia," found no difference across...

Jonah Lehrer was also Wrong About Antipsychotics

We spend a lot of time writing about knowledge dissemination in mental health, and over time, have increasingly recognized the important role of science...

Is Exercise Best for Depression?

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Time magazine reviews the evidence on exercise for depression, finding that exercise alters brain chemistry such that the brain shows less stress in response...