Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse

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In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

Beliefs About Illness and Rehabilitation Predict Outcome in Depression

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Researchers in Germany found that in a sample of 98 patients, beliefs about illness and rehabilitation predicted outcome for depression independent of medical or...

Antidepressants Have No Effect On Bipolar Depression

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In a review of 68 articles published between 2005 and 2011, Israeli researchers found that most well-controlled studies failed to show a significant effect of...

African-Americans More Likely to be Diagnosed Schizophrenic

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In a study of 610 psychiatric inpatients and outpatients from six academic medical centers across the United States, African Americans were almost three times...

England Seeks to Stop Antipsychotics For Dementia

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English health minister Paul Burstow is seeking to outlaw the 'silent scandal' of inappropriate antipsychotics for dementia by proposing legislation that imposes up to...

Cognitive Therapy Shown to be Effective For Schizophrenia

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Researchers report in the February issue of Archives of General Psychiatry that cognitive therapy improved both positive and negative symptoms in "low-functioning" patients with...

Voice Hearing as a Dissociative Rather Than Psychotic Phenomenon

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Researchers in England review in depth the evidence for voice hearing as dissociation, rather than psychosis, and suggest that voice hearing is a common...

Adverse Childhood Events Contribute Significantly to Most Mental Health Problems

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John Read and Richard Bentall write in the British Journal of Psychiatry about the growing understanding and acceptance of the significant role adverse childhood...

Bribery Alleged in Largest Antidepressant Study Ever Conducted

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A 2011 whistleblower complaint that was unsealed on January 20 of this year alleges that Forest Pharmaceuticals bribed a principle investigator of the STAR*D...

Assessing Increased Mortality Risks of Antipsychotics and Mood Stabilizers in Dementia

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An article in January's American Journal of Psychiatry weighs the relative risk of mortality associated with various antipsychotics and mood stabilizers used in the treatment of...

Religion and Spirituality Protect Against Depression

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In The American Journal of Psychiatry, a longitudinal study of 114 persons at high risk for depression found that those who reported more religiosity...

Psychosis is Not Unique to Schizophrenia

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In a sample of 3021 adolescents and young adults with anxiety or depression, Dutch researchers found that 27% also had one or more psychotic symptoms. Read...

Medications May Add to Mortality Rate in Schizophrenia

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Dutch researchers write in the Journal of Clinical Psychopharmacology that, in a prospective study of 7415 persons with diagnoses of schizophrenia, use of a first-generation...

Stress Associated With Brain Shrinkage in Healthy People

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In studies of healthy people experiencing stress, Yale researchers found tissue loss in brain areas regulating emotion, self-control and other behaviors.  Read more      ...

Early Trauma, Social Stress Accompany Psychosis

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Researchers at Emory University find that childhood trauma, sensitivity to psychosocial stress and a heightened biological response to stress are associated with the onset...

Discontinuing Psychotropics Reduces Falls in Elderly

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Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

Evidence That Sadness When Bereaved is Not Illness

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While the DSM-IV recognizes that depressive symptoms are sometimes normal in bereaved individuals, this "Bereavement Exclusion" is targeted for elimination from the DSM-V. However...

Why Marijuana Can Trigger Psychosis

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Brain scans by London researchers show why marijuana calms some people, but can cause psychosis or paranoid thoughts in others. They found that THC...

Antidepressants/Depression

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  A. The Natural Course of Depression Prior to the widespread use of antidepressants, the National Institute of Mental Health told the public that people regularly...

Mad In America’s Chapters

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Preface The World Health Organization has repeatedly found that people diagnosed with schizophrenia in the U.S. and other developed countries fare much worse than schizophrenia...

Antipsychotics and Chronic Illness

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A. The Chronicity Problem Becomes Apparent (1960s-1979s) It seems paradoxical that drugs that ameliorate acute psychotic symptoms over the short term will increase the likelihood...

Polypharmacy/Bipolar illness

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  A. Bipolar Illness Before the Psychopharmacology Era Prior to 1955, bipolar illness was a rare disorder. There were only 12,750 people  hospitalized with that disorder...

Outcomes in the Era of Atypical Antipsychotics

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Once second-generation antipsychotic drugs came on the market (which are known as “atypicals”), there were claims by psychiatric researchers that they would lead to...

A Rorschach Test for Psych Drugs

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On October 23, the New York Times ran a very nice feature story about a Los Angeles woman, Keris Myrick, who, even though she...

Now Antidepressant-Induced Chronic Depression Has a Name: Tardive Dysphoria

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Three recently published papers, along with a report by a Minnesota group on health outcomes in that state, provide new reason to mull over...