Antidepressants/Depression
A. The Natural Course of Depression
Prior to the widespread use of antidepressants, the National Institute of Mental Health told the public that people regularly...
Antipsychotics and Chronic Illness
A. The Chronicity Problem Becomes Apparent (1960s-1979s)
It seems paradoxical that drugs that ameliorate acute psychotic symptoms over the short term will increase the likelihood...
Polypharmacy/Bipolar illness
A. Bipolar Illness Before the Psychopharmacology Era
Prior to 1955, bipolar illness was a rare disorder. There were only 12,750 people hospitalized with that disorder...
Early Death Associated With Antipsychotics
There are a vast number of studies that document the diverse range of side effects caused by antipsychotic drugs. These adverse effects include brain...
Outcomes in the Era of Atypical Antipsychotics
Once second-generation antipsychotic drugs came on the market (which are known as “atypicals”), there were claims by psychiatric researchers that they would lead to...
A Research Timeline for Antipsychotic Drugs
1883 Phenothiazines developed as synthetic dyes
1934 USDA develops phenothiazines as insecticides
1938 Phenothiazines used to kill swine parasites
1949 ...
Antipsychotics/Schizophrenia
The long-term outcomes literature for antipsychotics, which has been compiled over a period of nearly 50 years, consistently tells of drugs that increase the...
