Opioids May Cause Depression and Worsen Chronic Pain

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“Converging lines of evidence now suggest that depression—a common comorbidity in the setting of chronic pain—may in some patients represent an unrecognized yet potentially reversible harm of opioid therapy.”

Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief

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The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).

New Data on the Adverse Effects of Meditation and Mindfulness

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Study reports on the less-examined findings of difficult and painful meditation-related experiences.

Research Finds Ketamine Does Not Reduce Delirium or Pain After Surgery

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Contrary to widely-held belief, a new rigorous trial finds that ketamine is ineffective for delirium and pain associated with surgery, and the drug carries harmful side effects.

Importance of Physical Symptoms in Mental Health Evals

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Researchers at Harvard Medical School highlight the need for mental health clinicians to explore the meaning of physical symptoms and pain