Opioids May Cause Depression and Worsen Chronic Pain

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ā€œConverging lines of evidence now suggest that depressionā€”a common comorbidity in the setting of chronic painā€”may in some patients represent an unrecognized yet potentially reversible harm of opioid therapy.ā€

Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief

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The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).

New Data on the Adverse Effects of Meditation and Mindfulness

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Study reports on the less-examined findings of difficult and painful meditation-related experiences.

Research Finds Ketamine Does Not Reduce Delirium or Pain After Surgery

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Contrary to widely-held belief, a new rigorous trial finds that ketamine is ineffective for delirium and pain associated with surgery, and the drug carries harmful side effects.

Importance of Physical Symptoms in Mental Health Evals

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Researchers at Harvard Medical School highlight the need for mental health clinicians to explore the meaning of physical symptoms and pain