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Placebos

When Placebos Beat
Active Treatment

May 24, 2013

U.K. researchers find, in a systematic literature review and meta-analysis of medical (not only psychiatric) treatments that when bias is ruled out and effects are considered on a continuous rather than binary basis, the effect of placebos can be superior to that of active treatments. Results appeared online in PLoS on May 15, 2013.

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Categorized in: Featured News, In the News, Placebos, Research

Psychiatric Drugs: an Increasing Portion of Prescription Costs

May 26, 2012

Rising prescriptions for psychiatric medications are partly a result of longer-term treatment and increasing population, according to an article by Joanna Moncrieff and Stephen Ilyas in the May, 2012 issue of British Journal of Psychiatry. Psych meds were an increasing proportion of all prescriptions in England between 1998 and 2010. Antipsychotics in particular, both costly and prescribed for uses beyond severe mental illness, are making an increasing contribution to total drug costs.

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Categorized in: Antidepressants, Antipsychotics, Benzodiazepines, In the News, Industry, Mood Stabilizers, Placebos, Psychiatric Drugs, Research, Stimulants

Post-Prozac Nation: The Science and History of Treating Depression

April 21, 2012

The Sunday New York Times Magazine traces the history and controversy around serotonin, “imbalance theory,” deep-brain stimulation and more; including references to Irving Kirsch and placebos, and David Healy.

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Categorized in: Adult, Antidepressants, Depression, Disorders, In the News, Industry, Placebos, Psychiatric Drugs, Research, Rethinking Psychiatry/Medical Model

Antidepressants and Advertising: Psychopharmaceuticals in Crisis

April 2, 2012

An article by written by faculty of the Harvard History of Science Department and the Program in Placebo Studies explores how “drug marketing portrays idealized scientific relationships between psychopharmaceuticals and depression … and how the placebo effect has become a critical issue in these debates, including the possible role of drug advertising to influence the placebo effect directly.” The article appears in the Yale Journal of Biology and Medicine.

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Categorized in: Antidepressants, In the News, Industry, Placebos, Psychiatric Drugs

Placebos In The News

March 29, 2012

A study that will appear in European Neuropsychopharmacology found that “the brain’s response to the placebo pill seems to depend … on whether or not the brain has ever ‘seen’ antidepressant medication before.” Similarly, an article in Medical Hypotheses proposes an approach that capitalizes on a “personal (as opposed to superficial or impersonal) encounter between helper and helpee” to potentiate the placebo response. A study in Schizophrenia Research investigates whether interventions can adequately identify and prevent relapse in placebo arms of trials and finds that, though relapse cannot be adequately identified or prevented, this fact is equally true for both placebo and continuous-treatment arms of trials and the longer-term recovery outcomes following relapse in both treatment and placebo conditions justify continued placebo trials.
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Categorized in: Antidepressants, In the News, Placebos, Psychiatric Drugs, Research

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