The Truth About Antidepressant Research: An Invitation to Dialogue

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The Finnish Psychological Association held a meeting in Helsinki on 1 Sept 2014 titled “Mental Health and Medicalization.” I spoke at the meeting and four days later I sent a letter to another speaker, psychiatrist Erkki Isometsä. Professor Isometsä replied: “I will respond to it in detail within a few days..." As "Open Dialogue" is essential in science, I have published my letter to Isometsä here as well as on my own website, although I didn’t succeed in starting a dialogue.

Researching the Link Between SSRIs and Violence

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In 2010, my 25-year old son was prescribed Prozac for depression. After a psychiatrist doubled his dose, my son became acutely psychotic and had to be admitted to the hospital. Over the next twelve months, during which time he was treated with antidepressants and neuroleptics, my son had five further psychotic experiences. I thought it might be that my son was having difficulty metabolising the drugs.

Report from the Parliament: Can Psychiatry At Least Be Curious?

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In the past six years, I have had the opportunity to speak at several conferences or meetings that I felt had particular potential to stir some political activity that would challenge current psychiatric practices, and one of those events was the meeting convened in the U.K.’s Parliament on May 11th, which had this title for the day: Rising Prescriptions, Rising Mental Health Disability: Is There a Link?

Dr. Pies and Dr. Frances Make a Compelling Case that Their Profession is Doing...

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Over the past two months, Ronald Pies and Allen Frances, in response to a post I had written, wrote several blogs that were meant to serve as an “evidence-based” defense of the long-term use of antipsychotics. As I read their pieces, I initially focused on that core argument they were presenting, but second time through, the aha moment arrived for me. Their blogs, when carefully parsed, make a compelling case that their profession, in their use of antipsychotics as a treatment for multiple psychotic disorders, has done great harm, and continues to do so today.

Call To Action: Massachusetts Bill H4062 for Informed Benzodiazepine Use is Official

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On February 24th, 2016 Bill HD4554 - An Act relative to benzodiazepines and non-benzodiazepine hypnotics was filed by Representative Paul McMurtry in the Massachusetts State House. The bill received 47 co-sponsors during the seven-day open period in which legislators can co-sponsor. This is an impressive and promising turnout.

Psychiatry’s Thalidomide Moment

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The authors of Study 329 began recruiting adolescents for a comparative study of Paxil, imipramine and placebo in 1994 and finished their investigations in 1997. They dropped a large number of their original cohort, so the randomness element in the study must be open to question. Late in 1998, SmithKline Beecham, the marketers of Paxil, acknowledged in an internal document that the study had shown that Paxil didn’t work for adolescents in terms of the two primary and six secondary outcomes they had established at the start of the study. In a nutshell, Study 329 was negative for efficacy and positive for harm, contrary to their succinct upbeat conclusion.

Neuroleptic Drugs And Mortality

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In November of last year, Schizophrenia Bulletin published a research study that, on the face of it, would seem to upset the notion that neuroleptic drugs are toxic and that their use markedly reduces life expectancy. There are, however, some problems with the study that need to be considered.

Yesterday I Looked Forward to Taking Psych Drugs

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People hassle me for being anti-medication, and I always tell them I am NOT anti-medication; I am pro-fully-informed choice. But people like things black-and-white. They see me as being against medications, and so I'm telling you why medications may have saved my life yesterday, or at least saved me a whole bunch more trouble.

Always a Mystery: Why do Drugs Come and Go?

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I’ve been teaching a course on substance abuse for about 30 years now. In this course, I cover a new drug class each week and always review the history of the drug. All of the drugs of abuse, cocaine, alcohol, marijuana, opiates are not new on the human scene. They date back to the Sumerians and the Greeks. The question for me is what accounts for epidemics? I have come to believe that epidemics are supplier driven rather than a function of consumer demand. For the current opiate epidemic, the suppliers were the pharmaceutical houses.

The Inherent Unreliability of the ADHD Label

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I imagine that everybody on this side of the issue knows by now that the eminent psychiatrist Jeffrey Lieberman, MD, Chief Psychiatrist at Columbia, and past President of the APA, called Robert Whitaker "a menace to society." The grounds for Dr. Lieberman's vituperation were that Robert had dared to challenge some of psychiatry's most sacred tenets! But in all the furor, it was largely ignored that in the same interview Dr. Lieberman had said something else that warrants additional discussion.

How Should We Understand the Link Between ADHD and Early Death?

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Alarming headlines, based on a recent study, declare that diagnosis with ADHD doubles the risk of early death. Psychiatrist Stephen Faraone, commenting on the original study published in the Lancet, concludes that: “for clinicians early diagnosis and treatment should become the rule rather than the exception.” This conclusion represents a false assumption that the deaths occurred in cases that were not treated.

You, Your Kids, or the Doctor… Who’s Running the Show?

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Let’s face it, as our kids slowly developing brains wrestle with behavioral and maturity issues while also trying to juggle expectations related to academic and social challenges, some of the behaviors they display can be quite concerning. Understandably, after trying what seems like everything in the books plus the kitchen, bathroom and laundry room sinks, caring and often exhausted parents are actively looking for help, resources and answers. But guess what? Without any need for pharmaceutical intervention or “drug therapy,” for centuries parents have been quite capable of helping challenged children overcome semi-annoying and concerning behaviors that some “experts” want to label today as symptoms of a mental disorder. Behaviors that a billion kids worldwide display every day.

Study 329: The Data Wars Cross the Rubicon

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It can be difficult to pinpoint transitions. The Rubicon that led from a Medical Republic to a Pharmaceutical Empire was crossed in 1962 with the passage of the Amendments to the Food and Drugs Act. This act put in place an apparatus of controlled trials, prescription-only status and disease indications that laid the basis for a global pharmaceutical hegemony, although the drift to Empire could still have been stopped at this point.

“The Human Cost of a Misleading Drug-Safety Study”

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Writing for the Atlantic, David Dobbs examines how much harm has been done in the 14 years since Paxil was wrongly determined to be safe and effective. “Study 329, as it became known, helped spur a huge increase in Paxil prescriptions,” Dobbs writes. “In 2002 alone, over 2 million prescriptions were written for children and teens, and many more for adults.” “Thousands of children, teens, and young adults attempted or committed suicide while on Paxil,” and the reanalysis of Study 329 in BMJ makes it seem “more likely than ever” that many did because of the drug.

Video: More Harm than Good Conference on Psychiatric Drugs

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On September 18th the one day "More Harm than Good Conference" brought together many of the leaders of the critical psychiatry movement. While the event has passed, the video and slides from the conference have been made available on the council for evidence-based psychiatry website.

What Happened to those Who Were Suicidal in Study 329? And to the Learned...

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In May 2014, the RIAT team asked GSK what the children who became suicidal in the course of Study 329 have since been told. The consent form says that anyone entering the study would be treated just the way they would be in normal clinical practice. In Study 329, the children taking imipramine were by design force titrated upwards to doses of the order of 300 mg, which is close to double the dose of imipramine given in adult trials by GSK or in normal clinical practice. In normal clinical practice it would be usual to inform somebody who had become suicidal on an SSRI that the treatment had caused their problem.

Summary of Recent Antidepressant Meta-Analyses

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On his own website, clinical psychologist Kenneth Pope has summarized 60 meta-analyses of antidepressants published between 2013-2015. The studies contain information on antidepressants “uses,...