Transparency and Outcome Reporting Not Improving in Behavioral Health Studies

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Randomized controlled trials published in four leading behavioral health journals show that new requirements for registering of trials does not seem to be improving trial design or transparency.

In Ireland, Antipsychotic Drugs Used Extensively On People With Learning Disabilities

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Over half of people with learning disabilities living in residential centers in Ireland are being prescribed antipsychotics.

Evidence Strengthening that Common Benzodiazepine Sedatives May Cause Dementia

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A meta-analysis of studies found that the risk of dementia increased 22% for every additional twenty daily doses of benzodiazepine medications annually.

SSRI Antidepressants Appear to Raise Risk of Serious Respiratory Disease in Newborns

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A new study has reinforced earlier warnings that taking SSRI antidepressants late in pregnancy appears to put mothers at a slightly increased risk of having newborns with persistent pulmonary hypertension.

Teen Brain Develops Differently in Bipolar Disorder, When Medicated

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The brains of adolescents diagnosed with bipolar disorder develop differently than the brains of teens without the disorder, according to a study in Biological...

Depression During Pregnancy, Unhealthy Diet, and Child Emotional Dysregulation

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One reason that depression is linked to later psychological problems in children could be because depressed mothers often have less healthy diets.

Not an Onion Study: First Three-month Injectable Antipsychotic Better Than Acute Withdrawal

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Not an Onion Study: The first-ever injectable antipsychotic that lasts for three months was approved based on one clinical trial in which it prevented relapses better than putting people into sudden withdrawal.

British Government Plans to Illegalize All Unapproved Psychoactive Substances

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A Kings College London psychiatrist worries what broad new British restrictions on psychoactive substances could mean for psychedelic research.

Antidepressants Do Work Well — We’ve Simply Been Evaluating Them Incorrectly

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Not an Onion Study: SSRI antidepressants did consistently outperform placebo in clinical trials, researchers discovered, so long as 16 of the 17 questions about patients' feelings are ignored.

Company Suing to Prevent Increased Drug Trial Transparency

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A company that conducts clinical drug trials for pharmaceutical companies is taking legal action against the UK government over transparency requirements.

Children’s Positive Responses to Antidepressants “Minimal” After Four Weeks

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Children's positive responses to SSRI antidepressant treatments for depression are even less significant than adult responses, and do not last beyond four weeks.

Why Would Depression Be Linked to a Doubling of Risk of Stroke?

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"Depression can double risk of stroke," reported many news outlets, covering a study by Harvard School of Public Health researchers in the Journal of the American Heart Association

Experts Shocked to Learn US Centers for Disease Control Taking Drug Company Funding

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The US government's Centers for Disease Control have been taking millions of dollars in drug company money.

Reanalysis of Data Shows Antidepressant Impacts on Depression “Not Clinically Significant”

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Irving Kirsch and Joanna Moncrieff have reanalyzed the clinical trial data on antidepressants.

Researchers Gain Insight into Stimulant Effects on Brain

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Researchers believe that they have gained a clearer understanding of how cocaine, amphetamines and related psychostimulant drugs "disrupt the normal functioning of the dopamine transporter in the brain."

Long-acting Injection No Better than Oral Antipsychotic

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A study of 5-year outcomes for people taking either an ordinary oral antipsychotic or a long-acting injection of an antipsychotic found no differences between the two.

Antipsychotics Safe During Pregnancy, After Corrective Algorithm

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There were some differences between the study, the abstract, the press release and the media coverage about the risks of taking antipsychotics during pregnancy.

FDA Updating Guidelines on Pregnancy and Drug Use

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The US FDA has launched a campaign to dispel the "myth" that women shouldn't be taking any medications while pregnant.

“Fuzzy Thinking” Common to Bipolar and Depression? Or to Psychotropics?

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Women diagnosed with bipolar or depression did not perform as well on tests measuring the ability to "sustain attention and respond quickly."

Common Sleep Aid Dangerous Due to Wide Misuse

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Zolpidem, the active ingredient in many common sleep aids, accounts for more emergency hospital visits than any other psychoactive drug.

Class Action Lawsuit Over Gambling, Sex Addiction Side Effects Settled

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The settlement of an Australian class action lawsuit about Pfizer Parkinson's drugs that caused severe gambling and sex addictions in 172 people has been delayed by a judge concerned that the plaintiffs were not fully informed of their rights.

National Initiative Launched to Get People Out of Prisons and Into Treatment

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The American Psychiatric Foundation has announced the launch of a pharmaceutical company-funded national initiative to move people from jails into psychiatric care.

Most Preschoolers with ADHD Stay on Meds for Years

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About 65% of preschool children who were diagnosed with ADHD and given stimulant drugs were still taking those drugs six years later.

Drug Company Suing FDA Over Right to Discuss Off-label Uses

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A manufacturer of a prescription omega-3 fatty acid derivative wants the right to tell physicians about benefits of its drug which the FDA has not approved.

Antidepressants Linked to Increased Risk of Preeclampsia in Pregnancy

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Pregnant women taking antidepressant medications, especially during the second trimester, have an increased risk of preeclampsia, a potentially serious or even fatal condition.