Antidepressant Withdrawal Symptoms Linked to Life-Altering Consequences, New Study Shows

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A new study reveals that withdrawal symptoms from antidepressants can last years, disrupting lives and relationships.
A cutout of a head as if made of blue paper. The head is full of pills.

Researchers: “We Do Not Suggest” Antipsychotics for Depression

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Augmenting with antipsychotics was no better at reducing suicide than adding antidepressants, but led to increased risk of death from other causes.

Open Dialogue Approach Reduces Future Need for Mental Health Services

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The Open Dialogue psychiatric treatment approach is associated with reduced utilization of mental and general health services for Danish youth.
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Exposure to Antidepressants in the Womb Makes for Sad, Scared Adolescents

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SSRI exposure in utero “alters the offspring’s brain structure,” causing a hyperactive amygdala and fear circuits, leading to anxiety and depression.
Illustration of person with hand to their head, which is dissolving into squares

Post-Acute Withdrawal Syndrome (PAWS): Why Don’t We Know More About It?

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Persistent antidepressant withdrawal is a debilitating experience, but little research exists about its prevalence and treatment.
An elderly man takes a pill

Elderly Patients Who Stop Antipsychotics Have Better Outcomes

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Older adults are often prescribed antipsychotics off-label for behavioral control in the hospital. But there’s no evidence for antipsychotics helping, and a great deal of evidence of harm.
Closeup of pills in hand, a magnifying glass

Psychiatric Drugs “A Crude Form of Chemical Restraint”

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Mental health nursing has a key role to play in helping people discontinue the drugs, writes Timothy Wand.
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Antidepressant Trials Last Eight Weeks, So Why Do We Take Them for Years?

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The studies are of short duration and are riddled with methodological issues like unblinding and failure to assess withdrawal.

Antidepressants in Dementia Patients Increase Risk of Death and Fractures

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A large-scale study reveals that antidepressant use is linked to faster cognitive decline in dementia patients, raising concerns about their widespread prescription.
Vector of a sick sad patient man in depression drowning in medications sitting inside a bottle.

Antidepressant Withdrawal Is Common and Debilitating

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Those using antidepressants long-term were more likely to experience withdrawal and to have severe withdrawal symptoms.
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Half of Those Who Take Antidepressants Are Labeled “Treatment Resistant”

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Millions of people are trying multiple antidepressant drugs without success, and psychiatry labels them “treatment resistant.”
Diagnosis: Placebo Effect

More Evidence That Antidepressants Work Via Placebo Effect

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Antidepressants were more effective for depressed patients who were more “optimistic.” Still, only 30% responded to SSRIs.

Are Antidepressants Weakening Women’s Bones?

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A study spanning two decades finds that antidepressant use is associated with a 44% increase in osteoporosis risk and a 62% higher chance of fractures.

New Study Links Antidepressants to Increased Risk of Diabetes

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Using genetic analysis, a new study finds that antidepressants—not depression—are responsible for a significant rise in type 2 diabetes risk.

Lithium Doubles Risk of Thyroid and Kidney Dysfunction

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Serum lithium levels lower than those considered therapeutic still conveyed increased risk.

Deadly Prescriptions: New Study Links Antipsychotics to Life-Threatening Risks in Dementia Patients

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With pharmaceutical companies pushing antipsychotics for off-label use, dementia patients are being put at risk for devastating health consequences. Research suggests safer alternatives exist—but why aren’t they being prioritized?

New Study Casts Doubt on Efficacy of Ketamine for Depression

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A new study, published this month in the Journal of Affective Disorders, investigated the effectiveness of weekly intravenous ketamine injections as a treatment for...
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Animal Study: SSRI Neurotoxic in Pregnancy

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Researchers: Fetal exposure to vilazodone hampers neurodevelopment and leads to "long-lasting neurodevelopmental impairments."

Benzodiazepines Linked to Suicide, Study Finds

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A new study finds that benzodiazepines—alprazolam (Xanax), lorazepam (Ativan), and diazepam (Valium)—are associated with an increased risk of suicidal events.

Hyperbolic Tapering off Antidepressants Limits Withdrawal

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New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.

Antidepressants No Better Than Placebo for About 85% of People

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Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Therapy Beats Drugs for Depression for Long-Term Outcomes

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Combining drugs and therapy also did not lead to better depression outcomes than therapy alone.

Randomized Controlled Trial Confirms That Antipsychotics Damage the Brain

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A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.

Reframing Antipsychotic Discontinuation: A Psychiatrist’s Personal and Professional Call for Epistemic Justice

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A psychiatrist with lived experience advocates for a more humane, collaborative approach to antipsychotic discontinuation that respects diverse ways of knowing.

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

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People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.