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Psychiatric Journals’ Pro-Pharma Publication Bias Hides Suicide Risk of Antidepressants

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Selective publication bias in top psychiatry journals was not explained by the quality of the studies, but by financial ties to pharma.

Hyperbolic Tapering off Antidepressants Limits Withdrawal

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New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.

SSRI Use During Pregnancy Alters the Child’s Brain Development

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Reduced brain volumes due to SSRI exposure in pregnancy was not explained by maternal depression alone.

What Is the Risk of Permanent Sexual Dysfunction from Antidepressants?

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Males taking antidepressants were at 100 times the risk of erectile dysfunction compared with the healthy population and more than three times the risk even after controlling for other variables.

Lexapro for Children: Drug With No Meaningful Benefit and Increased Suicidality Gets FDA Approval

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Response and remission rates were the same in the drug versus placebo groups, and Lexapro increased suicidality sixfold.

Randomized Controlled Trial Confirms That Antipsychotics Damage the Brain

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A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.
Top View of Girl Sits on Bed with Scattered Pills. Little Child Sitting on Gray Badcover Near Opened Packing of Medicines Keeps Head with Hands. Unhappy Childhood Concept

Antidepressants Increase Suicide Attempts in Youth; No Preventative Effect

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Researchers find that SSRIs increase suicide attempts up to age 24, and have no preventative effect at any age, even for those at high risk of suicide.

Understanding the Neurobiology of Post-SSRI Sexual Dysfunction

2
Post-SSRI sexual dysfunction (PSSD) may be a common adverse effect of antidepressants. Researchers are now attempting to understand the neurobiology behind it.

New Data Reveal the Full Extent of STAR*D Failure

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The initial study, which has been used to promote antidepressants, employed outcome switching to hide poor results.

Antidepressants, Antipsychotics, and Benzos All Increase Suicide Attempts in New Study

3
In a study of people with borderline personality disorder, only ADHD stimulants were associated with a decrease in suicide.

Robin Williams On Antidepressant at Time of Suicide

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Robin Williams had "therapeutic" levels of the tetra-cyclic antidepressant mirtazapine in his blood at the time of his suicide, according to the coroner's report...

Antidepressants No Better Than Placebo for About 85% of People

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Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Overuse of Psychiatric Drugs is Worsening Public Mental Health, Doctor Argues

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A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

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People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.

New Guidance on Antidepressant Withdrawal for Doctors in the UK

6
New guidance for primary care doctors in the UK on antidepressant discontinuation acknowledges severe and long-lasting withdrawal symptoms.
Letter blocks spelling "CANCER" and spilled pills in various colors on a white background

Cancer Risk Higher for Those on Clozapine

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The antipsychotic clozapine, considered the “gold-standard” treatment for psychosis, was found to increase the risk of blood and lymph system cancers.

No Benefit for Adding Antidepressants to CBT in Severe Depression

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For those with severe depression, inpatient CBT was effective but the adding antidepressants did not improve treatment outcomes.
The young patient at the reception in the hospital

Patients Express Anger at Doctors’ Ignorance About Antidepressant Withdrawal Effects

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Antidepressant users share their frustrations towards a healthcare system that overprescribes but is ill-equipped to support with discontinuation and withdrawal symptoms.

Prolonged Negative Impacts of Benzodiazepine Use Revealed in New Study

1
Researchers find that adverse effects often last over a year, with many users experiencing substantial life changes.
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Pharma CEO, Others Attempt Contradictory Critiques of Serotonin-Debunking Study

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Moncrieff et al. respond to the contradictory and, in some cases, false concerns raised by these critics of their serotonin review.

Study Highlights Lack of Evidence for Antidepressants in Treatment of Chronic Pain

1
A new Cochrane review details the lack of evidence for antidepressants in the treatment of chronic pain.

Addressing the Roots of Racial Trauma: An Interview with Psychologist Lillian Comas-DĂ­az

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MIA’s Hannah Emerson interviews Comas-Díaz on the need for culturally competent care in a medicalized and individualistic society.

Psychology is Not What You Think: An Interview with Critical Psychologist Ian Parker

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MIA’s Ayurdhi Dhar interviews Ian Parker about critical psychology, discourse and political action, and whether psychology has anything left to offer.
brain against blue dna strand with chemical structures

No Difference in Antidepressant Effectiveness After Genetic Testing

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Genetic testing may help reduce the length of time people experience the harmful effects of antidepressant drugs, but it is not helpful for predicting efficacy.

Prescribers Often Fail to Support Patients Discontinuing Antidepressants, Study Finds

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Study reveals most patients are dissatisfied with prescribers' support when discontinuing antidepressants.