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Growing rates of long-term psychiatric drug prescriptions and documented issues with withdrawal demonstrate a need for safe deprescribing practices.

Post-SSRI sexual dysfunction (PSSD) may be a common adverse effect of antidepressants. Researchers are now attempting to understand the neurobiology behind it.

Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.

A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.

Risk of depression increased when children were taking methylphenidate for ADHD, but once they stopped taking the drug, depression risk dropped to normal levels.

In a real-world setting, less than a quarter of patients diagnosed with depression improved with medication, hospitalization, and therapy.

Nassir Ghaemi: “Most psychiatric medications are purely symptomatic, with no known or proven effect on the underlying disease. They are like 50 variations of aspirin, used for fever or headache, rather than drugs that treat the causes of fever or headache.”

New guidance for primary care doctors in the UK on antidepressant discontinuation acknowledges severe and long-lasting withdrawal symptoms.

Leading ADHD researchers outline four mistakes that turned ADHD from a description of behavior into a medical disease.

When comparing kids with the same symptoms who were either diagnosed with ADHD or not, those who received the diagnosis had worse outcomes.

A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.

Babies born to mothers taking antidepressants during pregnancy were more than six times as likely to have neonatal withdrawal syndrome—including breathing problems, irritability/agitation, tremors, feeding problems, and seizures—than those born to mothers taking other types of drugs.

New study finds that people who felt they were coerced into being hospitalized were more likely to attempt suicide later.

In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

A new literature review reinforces the need to “down-titrate” or taper antidepressants, especially drugs like Celexa and Paxil.

Adults receiving ADHD medications and therapy frequently experience adverse events that interfere with employment and daily life.

Combining drugs and therapy also did not lead to better depression outcomes than therapy alone.

“Efforts to improve learning in children with ADHD should focus on obtaining effective academic instruction rather than stimulant medication.”

Robin Williams had "therapeutic" levels of the tetra-cyclic antidepressant mirtazapine in his blood at the time of his suicide, according to the coroner's report...

A new study suggests that taking antidepressants impairs empathy, while the experience of depression itself does not.

A new study promotes the use of a standardized approach to antidepressant tapering.

When the CDC released data revealing an increasing suicide rate in the US, some experts, speaking to major media outlets, speculated that the increase...

Paroxetine, SNRIs, and MAOIs were associated with the highest risk of withdrawal, as was long duration of use and whether the person experienced withdrawal in the past.

A new study in rats found that those exposed to antidepressants in utero had an impaired ability to nurture their own children in later life.