Saturday, November 28, 2020

More Evidence That Antipsychotics Shrink the Brain

European researchers who reviewed 43 imaging studies of first-episode psychosis found evidence that antipsychotics cause a decrease in gray matter volumes in the brain....

Cortisol Levels Increased in Youth at Risk for Psychosis

Researchers from Columbia University and the Institute of Neurosciences in Barcelona assessed cortisol levels in 33 patients at clinical high risk of psychosis. Cortisol...

Type of Treatment for Depression is Less Important than Engagement

An international team of researchers (including Irving Kirsch) found in a review "of 62 pivotal antidepressant trials consisting of data from 13,802 depressed patients"...

Pediatric Drugs: More Illness, But Less Research

An international team of researchers identified all drug trials registered in ClinicalTrials.gov between 2006 and 2011 and tracked the resulting publications, finding that although...

Happiness and First-Episode Schizophrenia

Canadian researchers find that 31 people with first-episode schizophrenia diagnoses were as happy as 29 controls, according to a self-reported questionnaire measuring happiness, life...

Top Docs Call Psych Diagnoses by Brain Scans “Modern Phrenology”

The Washington Post profiles Daniel Amen, "the most popular psychiatrist in America," who claims in copious books, DVDs, television and speaking engagements to be...

South Dakota Court Revives Cymbalta Suicide Case

A federal appeals court has reversed a lower court's summary judgment in favor of Eli Lilly,   allowing the parents of a South Dakota...

NIH Defends Nemeroff Grant, Issues Talking Points

When it awarded yet another multimillion-dollar grant to Charles Nemeroff, a key figure in the controversy over conflicts of interest involving pharmaceutical research, U.S....

GAO Calls for Patient-Centered Research, Public Comment

The Patient-Centered Outcomes Research Institute (PCORI)'s Methodology Committee released a report dated July 23, 2012, calling for "Standards for Patient-Centered Outcomes Research."  In a...

NE Journal of Medicine Backs Congressional Call for Research Transparency

Rep. Ed Markey (D-MA) introduced the Trial and Experimental Studies Transparency (TEST) Act into congress on August 2, 2012; a bill aimed at closing...

Nineteen New Zoloft Birth Defect Lawsuits Filed

Nineteen defective drug product liability cases against Prizer have been filed in West Virginia state court by mothers alleging that their children suffered from...

Antipsychotics Rise in Youth, But Hospitalization Rates Stay the Same

Researchers from Tufts and Harvard find in a review of 233 medical charts of psychiatrically hospitalized youth at three points in time (1991, 1998...

BJP Announces “The End of the Psychopharmacological Revolution”

The editor of the British Journal of Psychiatry, in a comment on Morrison et al.'s "Antipsychotics: is it Time to Introduce Patient Choice," announces...

Social Phobia is Not a Neuropsychological Deficit

Researchers at the University of Central Florida, saying "there are relatively few existing studies examining neuropsychological functioning in social phobia," found no difference across...

Only One in Seven Authors Disclose Conflict of Interest

Researchers from Harvard and the University of Melbourne identified physicians and scientists who had financial relationships with pharmaceutical companies named as defendants in U.S....

Antipsychotics for Childhood “Behavioral Problems” Skyrocket

Researchers from Columbia University and other New York institutions found a dramatically increasing use of antipsychotics to treat ADHD and other behavioral problems in...

Authors of BJP Editorial Critical of Antipsychotics Urge Reader Comment

The authors of a recent editorial in the British Journal of Psychiatry that urges a rethinking of the use of antipsychotics are asking that readers...

Is Exercise Best for Depression?

Time magazine reviews the evidence on exercise for depression, finding that exercise alters brain chemistry such that the brain shows less stress in response...

Pharma Execs Barred from Federal Programs

Three former executives from Purdue Pharma have been barred by a federal appeals court from doing business with federal healthcare programs such as Medicare...

U.K. Antidepressant Prescriptions Rise 9% in 2011

Almost 50 million prescriptions for antidepressants were issued in the U.K. in 2011, a rise of 9% over 2010. The increase is attributed, at...

Consumer Reports Recommends Against Antipsychotics for Depression

Consumer Reports recommends against antipsychotic "augmentation therapy" for depression. The consumer watchdog magazine finds that the unproven efficacy, harmful side effects, availability of alternatives,...

British Journal of Psychiatry Editorial Urges Rethinking the Use of Antipsychotics

The August issue of the British Journal of Psychiatry offers an editorial stating that, as "mental health services appear to have overestimated the strength...

Why Implausible Theories Persist in Evidence-Based Research.

David Weinberg writes in Science-Based Medicine that implausible theories must be held to a higher standard of proof in evidence-based research. In a review...

Former Drug Reviewer Speaks Out About FDA Failures

TruthOut interviews a former drug reviewer for the Center For Drug Evaluation and Research at the FDA, who says the center "placed the nation...

Antidepressant is Toxic to Fungus

Zoloft isn't just for depression any more; it also kills fungal meningitis. Researchers from Texas A&M find that "The problem for many current antifungal...

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