Research News

Summaries of research findings that tell of a scientific need to "rethink psychiatry."

EEG Shows That Mindfulness Based Cognitive Therapy Improves Brain Function in Bipolar Disorder

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In a study of 12 patients with bipolar disorder and 9 controls, researchers found that after an 8-week training in Mindfulness Based Cognitive Therapy...

Childhood Adversity Changes Stress-Related Gene Expression

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Researchers in Rhode Island and New Hampshire examined 99 healthy adults for changes related to stress hormones, and asked about their childhood attachment experiences....

1 in 4 Adults With a Mental Illness Has Been A Victim of Violence...

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In a meta-analysis funded by the World Health Organization and published in The Lancet, studies of 21,500 disabled individuals from Australia, Canada, New Zealand,...

Cumulative Risk of Impairment and Death From Anticholinergic Medication

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The New York Times reports that a two-year longitudinal study of over 13,000 men and women over 65 found that anticholinergic medications, which include many...

Deficits in Psychosis Linked To Childhood Trauma Via Brain Changes

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In a study of 83 patients and 63 controls, researchers in Norway and the U.K. investigated  deficits in attention, concentration, language and verbal intelligence...

The Depression Diagnosis Under Scrutiny

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Researchers in Denmark find that the diagnosis of depression in the DSM-IV contains at least 1,497 possible combinations of symptoms, with the potential for...

Paranoid Symptoms Arise From Social Phobia/Trauma

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In a 10-year longitudinal study of 3021 participants, researchers in The Netherlands, U.K., Germany and Switzerland find that paranoid symptoms are associated with social...

Schizophrenia, Trauma and The Immune System

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To test the hypothesis that a heightened immune system response associated with schizophrenia is also associated with childhood trauma, researchers in Ireland looked at...

Antipsychotics for Dementia: Not Justified and Risky

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In a study of antipsychotics used to treat 75,445 patients in nursing homes in the United States, researchers from Harvard Medical School, Columbia and...

NH Wins $10 Million to Expand Fitness Program

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New Hampshire's SHAPE program to promote physical fitness for the mentally ill has been so successful that the federal government has awarded $10 million...

Better Recovery and Less Relapse Without Meds: A 20-Year Study

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Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...

Psychosis as a Basic “Disturbance of Self”

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Researchers in Australia and the U.K. found that a basic disruption of the sense of ownership of one's experience and a lack of self-agency...

Criticism of the DSM Goes Mainstream

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Criticism of the upcoming revision of the DSM has gone mainstream, with Forbes Magazine weighing in on the economics of medicalizing grief, and Fox News questioning the...

Psychosis in the General Population

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Schizophrenia Bulletin explores "the extended psychosis phenotype," finding that affective dysregulation, psychotic experiences, motivational impairments, and cognitive alterations are distributed throughout the population, and suggestive...

Psychosis Overlaps With Anxiety and Depression

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In a representative community sample of 3021 adolescents and young adults, researchers in The Netherlands, Germany, Switzerland, and the U.K. found that 27% of...

Schizophrenia Bulletin Questions the “Psychosis Phenotype”

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In an editorial introducing its March issue, Schizophrenia Bulletin explores the categorical distinctions that have defined and directed research into psychotic disorders since the late 19th...

60 Minutes to Cover Antidepressant/Placebo Controversy This Sunday

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Lesley Stahl interviews Irving Kirsch of the Placebo Studies Program at Harvard Medical School this Sunday's edition of 60 Minutes. Stahl says the implication...

Some Avoid Antipsychotics Because They Value Psychosis

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Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...

Mindfulness-Based Cognitive Therapy is Effective in Bipolar Disorder

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Researchers at Massachusetts General Hospital and Harvard Medical School found that Mindfulness Based Cognitive Therapy increased mindfulness, lowered depressive mood symptoms, lessened attentional difficulties,...

Childhood Maltreatment Reduces Hippocampal Volume

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Researchers at Harvard University, in the largest and most detailed study on the topic to date, found that childhood maltreatment is significantly associated with...

Benzo Discontinuation Improves Quality of Life and Reduces Symptoms of Schizophrenia

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Researchers in Japan find that tapering or reducing benzodiazepines has a positive effect on quality of life, verbal and working memory, and psychiatric symptoms...

Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse

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In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

Beliefs About Illness and Rehabilitation Predict Outcome in Depression

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Researchers in Germany found that in a sample of 98 patients, beliefs about illness and rehabilitation predicted outcome for depression independent of medical or...

Antidepressants Have No Effect On Bipolar Depression

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In a review of 68 articles published between 2005 and 2011, Israeli researchers found that most well-controlled studies failed to show a significant effect of...

African-Americans More Likely to be Diagnosed Schizophrenic

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In a study of 610 psychiatric inpatients and outpatients from six academic medical centers across the United States, African Americans were almost three times...