Research News

Summaries of research findings that tell of a scientific need to "rethink psychiatry."

Antidepressant Withdrawal Symptoms Linked to Life-Altering Consequences, New Study Shows

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A new study reveals that withdrawal symptoms from antidepressants can last years, disrupting lives and relationships.

Therapist Empathy Predicts Success in Psychotherapy

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An updated meta-analysis reveals that therapist empathy is a predictor of better psychotherapy outcomes.

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

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People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.

Antidepressants No Better Than Placebo for About 85% of People

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Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Benzodiazepines Linked to Suicide, Study Finds

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A new study finds that benzodiazepines—alprazolam (Xanax), lorazepam (Ativan), and diazepam (Valium)—are associated with an increased risk of suicidal events.

“Medicine Is Awesome” Mentality Fueling Harmful Antidepressant Use, Say Experts

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The authors call for a paradigm shift in mental health care that emphasizes empathy, context, and alternatives to medication as first-line treatments for depression.

Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants

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In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

Psychiatry and the Selves We Might Become: An Interview with Sociologist Nikolas Rose

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MIA’s Ayurdhi Dhar interviews the well-known sociologist of medicine, Nikolas Rose, about the role psychiatry plays in shaping how we manage ourselves and our world.
A cutout of a head as if made of blue paper. The head is full of pills.

Researchers: “We Do Not Suggest” Antipsychotics for Depression

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Augmenting with antipsychotics was no better at reducing suicide than adding antidepressants, but led to increased risk of death from other causes.

Randomized Controlled Trial Confirms That Antipsychotics Damage the Brain

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A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.
burnt matches in a line

No Subgroup of Patients for Whom Antidepressants Are Effective

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A reanalysis of STAR*D finds no support for the theorized subgroup of patients who do well on antidepressants.

Researcher Acknowledges His Mistakes in Understanding Schizophrenia

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Sir Robin Murray, a professor at the Institute of Psychiatry, Psychology, and Neuroscience in London, states that he ignored social factors that contribute to ‘schizophrenia’ for too long. He also reports that he neglected the negative effects antipsychotic medication has on the brain.

Antipsychotics Increase Risk of Dementia; New Research Illuminates Why

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In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

For People “At Risk for Psychosis,” Antipsychotics Associated with Worse Outcomes

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Researchers studied whether antipsychotics could prevent transition to full psychosis and found that the drugs worsened outcomes.
Illustration of person with hand to their head, which is dissolving into squares

Post-Acute Withdrawal Syndrome (PAWS): Why Don’t We Know More About It?

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Persistent antidepressant withdrawal is a debilitating experience, but little research exists about its prevalence and treatment.

Hyperbolic Tapering off Antidepressants Limits Withdrawal

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New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.
Miniature people - The worker at work with medicine pills

Antidepressant Trials Last Eight Weeks, So Why Do We Take Them for Years?

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The studies are of short duration and are riddled with methodological issues like unblinding and failure to assess withdrawal.

Psychologist Debunks Common Misconceptions of Maslow’s Hierarchy

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Utilizing Maslow’s published books and essays, psychologist William Compton delineates common myths and attempts to respond to them.

Overuse of Psychiatric Drugs is Worsening Public Mental Health, Doctor Argues

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A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.

Antidepressant Use Leads to Worse Long Term Outcomes, Study Finds

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Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.

Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics

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Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.
Vector of a sick sad patient man in depression drowning in medications sitting inside a bottle.

Antidepressant Withdrawal Is Common and Debilitating

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Those using antidepressants long-term were more likely to experience withdrawal and to have severe withdrawal symptoms.
Scowling teenage boy holding up pills sealed in blister packs in his hand as he leans on a wooden table with an intense stare

Risk of Depression Spikes When Kids Take Ritalin

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Risk of depression increased when children were taking methylphenidate for ADHD, but once they stopped taking the drug, depression risk dropped to normal levels.

New Data on the Adverse Effects of Meditation and Mindfulness

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Study reports on the less-examined findings of difficult and painful meditation-related experiences.

Are Students Benefiting From the Growth Mindset Model?

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Results from two meta-analyses reveal shortcomings with the growth mindset theory as applied in schools.