Research News

Summaries of research findings that tell of a scientific need to "rethink psychiatry."

A cutout of a head as if made of blue paper. The head is full of pills.

Researchers: “We Do Not Suggest” Antipsychotics for Depression

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Augmenting with antipsychotics was no better at reducing suicide than adding antidepressants, but led to increased risk of death from other causes.
Illustration of person with hand to their head, which is dissolving into squares

Post-Acute Withdrawal Syndrome (PAWS): Why Don’t We Know More About It?

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Persistent antidepressant withdrawal is a debilitating experience, but little research exists about its prevalence and treatment.
An elderly man takes a pill

Elderly Patients Who Stop Antipsychotics Have Better Outcomes

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Older adults are often prescribed antipsychotics off-label for behavioral control in the hospital. But there’s no evidence for antipsychotics helping, and a great deal of evidence of harm.
Illustration of a person cringing while surrounded by ghostly figures

Exposure to Antidepressants in the Womb Makes for Sad, Scared Adolescents

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SSRI exposure in utero “alters the offspring’s brain structure,” causing a hyperactive amygdala and fear circuits, leading to anxiety and depression.

Antidepressant Withdrawal Symptoms Linked to Life-Altering Consequences, New Study Shows

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A new study reveals that withdrawal symptoms from antidepressants can last years, disrupting lives and relationships.
Vector of a sick sad patient man in depression drowning in medications sitting inside a bottle.

Antidepressant Withdrawal Is Common and Debilitating

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Those using antidepressants long-term were more likely to experience withdrawal and to have severe withdrawal symptoms.

Systemic Violence and the Mental Health Industrial Complex

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A recent paper, by Dr. Eric Greene, builds upon critiques of the biomedical model and illustrates how the mental health industrial complex overmedicates, stigmatizes,...

Hyperbolic Tapering off Antidepressants Limits Withdrawal

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New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.

Therapy Beats Drugs for Depression for Long-Term Outcomes

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Combining drugs and therapy also did not lead to better depression outcomes than therapy alone.

Robin Williams On Antidepressant at Time of Suicide

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Robin Williams had "therapeutic" levels of the tetra-cyclic antidepressant mirtazapine in his blood at the time of his suicide, according to the coroner's report...

Randomized Controlled Trial Confirms That Antipsychotics Damage the Brain

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A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.

Researchers Search for Subgroups Where Antidepressants Are More Effective

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The researchers theorized that this increased effectiveness was due not to “antidepressant” properties, but rather to the drug’s side effects, which include insomnia, drowsiness, and nausea.

Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants

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In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

From EMPOWER to Exercise: What Actually Helps Older Adults Quit Benzos?

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Despite clear risks, benzos and z-drugs remain widely prescribed to the elderly. New research explores what helps—and what doesn’t—when trying to stop.

Benzodiazepines Linked to Suicide, Study Finds

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A new study finds that benzodiazepines—alprazolam (Xanax), lorazepam (Ativan), and diazepam (Valium)—are associated with an increased risk of suicidal events.
A person, out of focus, holding a pill bottle in focus

Half of Those Who Take Antidepressants Are Labeled “Treatment Resistant”

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Millions of people are trying multiple antidepressant drugs without success, and psychiatry labels them “treatment resistant.”
Closeup of pills in hand, a magnifying glass

Psychiatric Drugs “A Crude Form of Chemical Restraint”

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Mental health nursing has a key role to play in helping people discontinue the drugs, writes Timothy Wand.

Antipsychotics Increase Risk of Dementia; New Research Illuminates Why

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In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

Open Dialogue Approach Reduces Future Need for Mental Health Services

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The Open Dialogue psychiatric treatment approach is associated with reduced utilization of mental and general health services for Danish youth.

Antidepressants No Better Than Placebo for About 85% of People

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Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.
Miniature people - The worker at work with medicine pills

Antidepressant Trials Last Eight Weeks, So Why Do We Take Them for Years?

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The studies are of short duration and are riddled with methodological issues like unblinding and failure to assess withdrawal.

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

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People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.
Diagnosis: Placebo Effect

More Evidence That Antidepressants Work Via Placebo Effect

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Antidepressants were more effective for depressed patients who were more “optimistic.” Still, only 30% responded to SSRIs.

Psychologist Debunks Common Misconceptions of Maslow’s Hierarchy

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Utilizing Maslow’s published books and essays, psychologist William Compton delineates common myths and attempts to respond to them.

Antidepressants in Dementia Patients Increase Risk of Death and Fractures

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A large-scale study reveals that antidepressant use is linked to faster cognitive decline in dementia patients, raising concerns about their widespread prescription.