Research News

Summaries of research findings that tell of a scientific need to "rethink psychiatry."

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Antidepressant Trials Last Eight Weeks, So Why Do We Take Them for Years?

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The studies are of short duration and are riddled with methodological issues like unblinding and failure to assess withdrawal.

Antidepressant Withdrawal Symptoms Linked to Life-Altering Consequences, New Study Shows

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A new study reveals that withdrawal symptoms from antidepressants can last years, disrupting lives and relationships.
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Psychiatric Drugs “A Crude Form of Chemical Restraint”

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Mental health nursing has a key role to play in helping people discontinue the drugs, writes Timothy Wand.

Therapy Beats Drugs for Depression for Long-Term Outcomes

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Combining drugs and therapy also did not lead to better depression outcomes than therapy alone.

Hyperbolic Tapering off Antidepressants Limits Withdrawal

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New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.

Researchers Search for Subgroups Where Antidepressants Are More Effective

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The researchers theorized that this increased effectiveness was due not to “antidepressant” properties, but rather to the drug’s side effects, which include insomnia, drowsiness, and nausea.
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Animal Study: SSRI Neurotoxic in Pregnancy

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Researchers: Fetal exposure to vilazodone hampers neurodevelopment and leads to "long-lasting neurodevelopmental impairments."

Antidepressants No Better Than Placebo for About 85% of People

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Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants

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In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

Randomized Controlled Trial Confirms That Antipsychotics Damage the Brain

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A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.

New Study Links Antidepressants to Increased Risk of Diabetes

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Using genetic analysis, a new study finds that antidepressants—not depression—are responsible for a significant rise in type 2 diabetes risk.

Robin Williams On Antidepressant at Time of Suicide

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Robin Williams had "therapeutic" levels of the tetra-cyclic antidepressant mirtazapine in his blood at the time of his suicide, according to the coroner's report...

Overuse of Psychiatric Drugs is Worsening Public Mental Health, Doctor Argues

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A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.

Antidepressants in Dementia Patients Increase Risk of Death and Fractures

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A large-scale study reveals that antidepressant use is linked to faster cognitive decline in dementia patients, raising concerns about their widespread prescription.

Benzodiazepines Linked to Suicide, Study Finds

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A new study finds that benzodiazepines—alprazolam (Xanax), lorazepam (Ativan), and diazepam (Valium)—are associated with an increased risk of suicidal events.

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

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People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.

Antidepressants Linked to Lasting Sexual Dysfunction, Study Finds

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New research highlights the challenges in quantifying the prevalence of Post-SSRI Sexual Dysfunction (PSSD), a condition that continues to affect patients long after they stop taking antidepressants.

Antidepressants Blunt Ability to Feel Empathy

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A new study suggests that taking antidepressants impairs empathy, while the experience of depression itself does not.

Open Dialogue Approach Reduces Future Need for Mental Health Services

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The Open Dialogue psychiatric treatment approach is associated with reduced utilization of mental and general health services for Danish youth.

Long-term Use of Lithium Can Cause Kidney Failure

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A third of patients who have taken the common psychiatric medication lithium for over ten years have developed "chronic renal failure" from the drug.

Lithium Doubles Risk of Thyroid and Kidney Dysfunction

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Serum lithium levels lower than those considered therapeutic still conveyed increased risk.

Are Antidepressants Weakening Women’s Bones?

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A study spanning two decades finds that antidepressant use is associated with a 44% increase in osteoporosis risk and a 62% higher chance of fractures.

Deadly Prescriptions: New Study Links Antipsychotics to Life-Threatening Risks in Dementia Patients

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With pharmaceutical companies pushing antipsychotics for off-label use, dementia patients are being put at risk for devastating health consequences. Research suggests safer alternatives exist—but why aren’t they being prioritized?

Transcranial Magnetic Stimulation No Better Than Placebo for Treatment-Resistant Depression

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A new study in JAMA Psychiatry found that transcranial magnetic stimulation was no better than placebo for treatment-resistant depression.

Involuntary Hospitalization Increases Risk of Suicide, Study Finds

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New study finds that people who felt they were coerced into being hospitalized were more likely to attempt suicide later.