Research

During the 1970s, the head of schizophrenia studies at the NIMH, Loren Mosher, conducted an experiment that compared treatment in a homelike environment (called...

Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated? Rappaport, M. International Pharmacopsychiatry, 13 (1978), 100-111. In this 1978 study,  Maurice Rappaport and his colleagues at...

The Treatment of Acute Schizophrenia Without Drugs. Carpenter, W. American Journal of Psychiatry, 134 (1977), 14-20. In this 1977 NIMH study, 49 schizophrenia patients placed into an experimental...

Comparison of Two Five-Year Follow-up Studies.Bockoven, J. American Journal of Psychiatry, 132 (1975), 796-801. In this study, Boston psychiatrists Sanbourne Bockoven and Harry Solomon compared relapse rates...

Discontinuation of Chemotherapy for Chronic Schizophrenics. Prien, R. Hospital and Community Psychiatry, 22 (1971), 20-23. In this NIMH study, the earlier finding that relapse rates rose in...

Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication. Prien, R. British Journal of Psychiatry, 115 (1968), 679-86. The critical finding of this NIMH study  was that...

a)  One Year After Discharge. Schooler, N. American Journal of Psychiatry, 123 (1967):986-995. This NIMH study looked at one-year outcomes for 299 patients who had been treated either...

Harvard researchers investigated 6,214 cases of major depression for factors that would predict transition to bipolar disorder.  Clinical characteristics such as age of onset...

In a prospective study of 28 outpatients with major depression, Canadian researchers investigated whether brain volume changes stabilized with antidepressant treatment and/or reversed with...

Nancy Andreasen's 2003 study finding ongoing brain changes in persons with schizophrenia diagnoses, despite antipsychotic drug treatment. Article →             ...

1978 study of 80 young males diagnosed with acute schizophrenia, finding that "many unmedicated-while-in-hospital patients showed greater long-term improvement, less pathology at follow-up, fewer...

In a review of 681 studies comparing use of antipsychotic medication with placebo, milieu, or psychosocial treatment in first- or second-episode schizophrenia spectrum disorders,...

Senator Charles Grassley (R-Iowa) "inappropriate prescriptions." Finds "shocking" that medicaid prescribers write "more prescriptions than seems humanly possible." Read more            ...

Taiwanese researchers found that second-generation antipsychotics increased the risk of pneumonia in a sample of 33,024 inpatients. Read more              ...

In a study of 33,024 Taiwanese inpatients, researchers found there was a 3.18 times higher, dose-dependent risk of pneumonia associated with clozapine. Quetiapine, olanzapine,...

A 2006 study in the journal Psychotherapy and Psychosomatics finds that 100% of schizophrenia and mood disorder experts and over 80% of other experts advising...

Book by Joseph Glenmullen, a "Step-by-Step Guide to Safely Overcoming Antidepressant Withdrawal, Dependence and 'Addiction.'" Go to Amazon                ...

Will Hall's Harm Reduction Guide, published by the Icarus Project and Freedom Center.

Alternatives Beyond Psychiatry is a "book of alternatives around the world. (Ex-) users and survivors of psychiatry, therapists, psychiatrists, lawyers, social scientists and relatives report...

May, 2003 article in the New York Times questioning the promise of second-generation antipsychotics. Go to New York Times              ...

An overview of 52 randomized controlled trials of conventional v. atypical antipsychotics in a total of 12,649 patients, published in the British Medical Journal in...

Compendium of experience from 28 people around the world who have gone through withdrawal, along with the contributions of eight professionals on how they...

Joanna Moncrieff's 2006 paper in Medical Hypotheses discusses the possibility that the research on maintenance and discontinuation of medication is flawed because it fails...

Go to "Complementary and Alternative Medicine Treatments in Psychiatry" →                                ...

Article in the Journal of Psychiatric and Mental Health Nursing Go to "Addressing Non-Adherence to Antipsychotic Medication: A Harm Reduction Approach"          ...