Tuesday, February 7, 2023

Tag: major depressive disorder

Judge Rules No More Drugging Migrant Children Without Consent

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From MSN News: "A federal judge on Monday found that U.S. government officials have been giving psychotropic medication to migrant children at a Texas...

Researchers Challenge Industry-Friendly Depression Guideline

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Review of a new mixed depression guideline reveals financial bias of guideline developers and lack of evidence supporting recommendations for prescribing of antipsychotics.

Major Depressive Disorder and “the Confusion of Tongues…”

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The 1 Boring Old Man blog discusses how MDD started as a “Descriptor, then became a Disorder, then became a Brain Disease, and now seems have...

Meditation and Exercise Reduce Depression Symptoms 40%

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A combination of exercise and meditation done twice a week over two months may reduce depression symptoms by 40 percent, according to a new study published open-access this month in Translational Psychiatry. Following the eight-week intervention, the student participants that had previously been diagnosed with major depressive disorder (MDD) reported significantly less symptoms and ruminative thoughts and students without any such diagnoses also showed remarkable improvements.

Antidepressants Not More Effective Than Therapy for Major Depression

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A new study, published this week in BMJ, found no major differences in the effectiveness of cognitive behavioral therapy (CBT) and antidepressants. When the researchers compared previous studies, they found no major differences in relapse rates or level of treatment response between those taking antidepressants and those undergoing CBT.

Large-Scale Study Reveals Arbitrariness of DSM Depression Diagnosis

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A new study on the depression symptoms of over three-thousand patients challenges the criteria used for diagnosing major depression with the latest Diagnostic and Statistical Manual (DSM-5). Current diagnostic systems are based on an assumption that the symptoms of depression point to a common underlying “illness," but research suggests that this framework may be outdated and oversimplified.

Antidepressants’ Superiority to Placebo in Major Depression Challenged By Reanalysis

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The October edition of the Journal of World Psychiatry, the 3rd ranked journal of Psychiatry, will publish a reanalysis of antidepressant efficacy versus placebo in major depression. When the researchers, Arif Khan and Walter Brown, analyzed the data from the FDA archives for antidepressants approved between 1985 and 1997, “it was evident that the conventional wisdom of 70% response with antidepressants was at best an overestimate.” In fact, “the magnitude of symptom reduction was about 40% with antidepressants,” compared to “about 30% with placebo.”