Thursday, November 21, 2019

Risk of Death in the Elderly Trebled With Antipsychotics

In a nine-year study of all 2,224 residents of Leppävirta, Finland who were 65 years old or older, researchers found that the 332 residents...

Psychotropics Accelerate Cognitive and Functional Decline

Researchers at Johns Hopkins, The Mayo Clinic, Harvard Medical School, Duke and others found in a study of 230 Alzheimer's patients tracked over four...

Early Environment Influences Schizophrenia Independent of Genetic Risk

Canadian researchers found that childhood adversity and other environmental factors such as family instability and cannabis use was associated with the development of schizophrenia,...

Oxytocin Improves Emotion Recognition in Schizophrenia

Oxytocin, a natural hormone with a role in social behaviors, has been shown to improve social behaviors in people with autistic spectrum disorders and...

Antidepressant Use Associated with Brain Atrophy and Lesions in Elderly

In a study of 630 elderly Manhattanites without dementia, researchers from the Netherlands found that antidepressant use was associated with significantly more brain atrophy,...

Review of Evidence for Non-Pharmacological Treatment of Depressive Disorders

Researchers in Germany review and evaluate the evidence for non-pharmacological treatment of depressive disorders, finding an "adequate level of evidence" for psychotherapeutic intervention, marital/couples/family...

Serotonin and Depression: A Disconnect Between the Advertisements and the Scientific Literature

MIA bloggers Jonathan Leo and Jeffrey Lacasse review the Serotonin Hypothesis as represented in advertising and as verified in scientific literature, finding a disturbing...

Mental Illness Mortality is Climbing

Mortality rates in schizophrenia and bipolar patients in the year after hospitalization were about double the national average and rising, according to this study...

EEG Shows That Mindfulness Based Cognitive Therapy Improves Brain Function in Bipolar Disorder

In a study of 12 patients with bipolar disorder and 9 controls, researchers found that after an 8-week training in Mindfulness Based Cognitive Therapy...

Deficits in Psychosis Linked To Childhood Trauma Via Brain Changes

In a study of 83 patients and 63 controls, researchers in Norway and the U.K. investigated  deficits in attention, concentration, language and verbal intelligence...

The Depression Diagnosis Under Scrutiny

Researchers in Denmark find that the diagnosis of depression in the DSM-IV contains at least 1,497 possible combinations of symptoms, with the potential for...

Paranoid Symptoms Arise From Social Phobia/Trauma

In a 10-year longitudinal study of 3021 participants, researchers in The Netherlands, U.K., Germany and Switzerland find that paranoid symptoms are associated with social...

Schizophrenia, Trauma and The Immune System

To test the hypothesis that a heightened immune system response associated with schizophrenia is also associated with childhood trauma, researchers in Ireland looked at...

Antipsychotics for Dementia: Not Justified and Risky

In a study of antipsychotics used to treat 75,445 patients in nursing homes in the United States, researchers from Harvard Medical School, Columbia and...

Better Recovery and Less Relapse Without Meds: A 20-Year Study

Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...

Psychosis as a Basic “Disturbance of Self”

Researchers in Australia and the U.K. found that a basic disruption of the sense of ownership of one's experience and a lack of self-agency...

Criticism of the DSM Goes Mainstream

Criticism of the upcoming revision of the DSM has gone mainstream, with Forbes Magazine weighing in on the economics of medicalizing grief, and Fox News questioning the...

Psychosis in the General Population

Schizophrenia Bulletin explores "the extended psychosis phenotype," finding that affective dysregulation, psychotic experiences, motivational impairments, and cognitive alterations are distributed throughout the population, and suggestive...

Psychosis Overlaps With Anxiety and Depression

In a representative community sample of 3021 adolescents and young adults, researchers in The Netherlands, Germany, Switzerland, and the U.K. found that 27% of...

Schizophrenia Bulletin Questions the “Psychosis Phenotype”

In an editorial introducing its March issue, Schizophrenia Bulletin explores the categorical distinctions that have defined and directed research into psychotic disorders since the late 19th...

Some Avoid Antipsychotics Because They Value Psychosis

Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...

Mindfulness-Based Cognitive Therapy is Effective in Bipolar Disorder

Researchers at Massachusetts General Hospital and Harvard Medical School found that Mindfulness Based Cognitive Therapy increased mindfulness, lowered depressive mood symptoms, lessened attentional difficulties,...

Childhood Maltreatment Reduces Hippocampal Volume

Researchers at Harvard University, in the largest and most detailed study on the topic to date, found that childhood maltreatment is significantly associated with...

Benzo Discontinuation Improves Quality of Life and Reduces Symptoms of Schizophrenia

Researchers in Japan find that tapering or reducing benzodiazepines has a positive effect on quality of life, verbal and working memory, and psychiatric symptoms...

Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse

In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

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