Thursday, April 9, 2020

Diagnosing Conflict-of-Interest Disorder

Article by Lisa Cosgrove from June, 2010 reviewing conflicts of interest related to the DSM. Article →                 ...

Effort to Curb Antipsychotics for Dementia Announced

The Centers for Medicare and Medicaid Services is launching an initiative to curb the use of antipsychotic medications for nursing home residents with dementia....

Anhedonia in Schizophrenia Reflects Beliefs, Not Deficits

Researchers at the University of Maryland investigated "the emotion paradox" in schizophrenia; the tendency of individuals with schizophrenia to report similar levels of positive...

Mindfulness-Based Therapy for Psychosis

Researchers in Amsterdam investigated the use of a mindfulness-based therapy for 16 people recovering from a recent experience of first-episode psychosis.  13 completed the...

Recovery Involves Social Support, Self-Reliance, and Trust

Researchers in Brazil followed sixteen individuals after a first-episode psychotic experience to understand their subjective experience of recovery.  They found that the participants described...

Ritalin Impairs Learning and Memory

Ritalin reduced impulsive responses and increased the amount of time willing to stay on task of Rhesus monkeys in a study from the University...

$1 Billion J&J Settlement Rejected as Insufficient

Federal prosecutors have rejected as insufficient the $1 billion settlement reached two months ago between Johnson & Johnson and prosecutors in Philadelphia to resolve...

Women on SSRIs Less Likely To Breastfeed

In a prospective cohort study of 466 pregnant women over 10 years, researchers at the California Teratogen Information Service found that women exposed to...

Activity-Based Therapies Reduce Antipsychotic Use

Researchers from the University of North Carolina found that activity-based therapy and care reduced the use of antipsychotics in a study of 107 people...

Increased Expectancy Explains Improved Response in Antidepressant Trials

Article →                                                ...

Sensitivity to Threatening Faces Predicts Depression

Researchers in China found that among 27 young adults with early-onset major depressive disorder matched against 25 healthy controls, MRI detected elevated response in...

Overprescribing of Benzodiazepines

Norwegian researchers found that 14.6% (27,861) of patients who were prescribed benzodiazepines used two simultaneously, despite the fact that all benzodiazepines have essentially the...

MRI Studies

During the 1990s, researchers using MRI technology discovered that antipsychotics shrink the frontal lobes and cause an enlargement of the basal ganglia. In the...

One Hundred Years of Schizophrenia

One Hundred Years of Schizophrenia. Hegerty, J. American Journal of Psychiatry 151 (1994):1409-1416. In 1994, Harvard Medical School researchers reported that outcomes for schizophrenia patients in the U.S....

The Vermont Longitudinal Study & Correction of Seven Myths

In a long-term study of schizophrenia patients released during the late 1950s and early 1960s from the back wards of Vermont State Hospital, Courtenay...

Schizophrenia: Manifestations, Incidence and Course in Different Cultures

Schizophrenia: Manifestations, Incidence and Course in Different Cultures.Jablensky, A. Psychological Medicine, supplement 20 (1992):1-95. The second WHO study was called the Determinants of Outcome of Severe...

The International Pilot Study of Schizophrenia

The International Pilot Study of Schizophrenia. Leff, J.Psychological Medicine, 22 (1992):131-145. The first World Health Organization study that compared schizophrenia outcomes in "developed" and "developing" countries...

Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated?

Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated? Rappaport, M. International Pharmacopsychiatry, 13 (1978), 100-111. In this 1978 study,  Maurice Rappaport and his colleagues at...

The Treatment of Acute Schizophrenia Without Drugs

The Treatment of Acute Schizophrenia Without Drugs. Carpenter, W. American Journal of Psychiatry, 134 (1977), 14-20. In this 1977 NIMH study, 49 schizophrenia patients placed into an experimental...

Comparing five-year outcomes in the pre-Thorazine era and the post-Thorazine era.

Comparison of Two Five-Year Follow-up Studies.Bockoven, J. American Journal of Psychiatry, 132 (1975), 796-801. In this study, Boston psychiatrists Sanbourne Bockoven and Harry Solomon compared relapse rates...

Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication

Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication. Prien, R. British Journal of Psychiatry, 115 (1968), 679-86. The critical finding of this NIMH study  was that...

Environmental Factors Drive Mania

Harvard researchers investigated 6,214 cases of major depression for factors that would predict transition to bipolar disorder.  Clinical characteristics such as age of onset...

Brain Volume Recovers With Remission, Not With Medication

In a prospective study of 28 outpatients with major depression, Canadian researchers investigated whether brain volume changes stabilized with antidepressant treatment and/or reversed with...

Ongoing Brain Changes With Antipsychotic Treatment

Nancy Andreasen's 2003 study finding ongoing brain changes in persons with schizophrenia diagnoses, despite antipsychotic drug treatment. Article →             ...

Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated?

1978 study of 80 young males diagnosed with acute schizophrenia, finding that "many unmedicated-while-in-hospital patients showed greater long-term improvement, less pathology at follow-up, fewer...

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