Ritalin Impairs Learning and Memory

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Ritalin reduced impulsive responses and increased the amount of time willing to stay on task of Rhesus monkeys in a study from the University...

$1 Billion J&J Settlement Rejected as Insufficient

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Federal prosecutors have rejected as insufficient the $1 billion settlement reached two months ago between Johnson & Johnson and prosecutors in Philadelphia to resolve...

Women on SSRIs Less Likely To Breastfeed

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In a prospective cohort study of 466 pregnant women over 10 years, researchers at the California Teratogen Information Service found that women exposed to...

Activity-Based Therapies Reduce Antipsychotic Use

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Researchers from the University of North Carolina found that activity-based therapy and care reduced the use of antipsychotics in a study of 107 people...

Increased Expectancy Explains Improved Response in Antidepressant Trials

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Article →                                                ...

Sensitivity to Threatening Faces Predicts Depression

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Researchers in China found that among 27 young adults with early-onset major depressive disorder matched against 25 healthy controls, MRI detected elevated response in...

Overprescribing of Benzodiazepines

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Norwegian researchers found that 14.6% (27,861) of patients who were prescribed benzodiazepines used two simultaneously, despite the fact that all benzodiazepines have essentially the...

MRI Studies

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During the 1990s, researchers using MRI technology discovered that antipsychotics shrink the frontal lobes and cause an enlargement of the basal ganglia. In the...

One Hundred Years of Schizophrenia

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One Hundred Years of Schizophrenia. Hegerty, J. American Journal of Psychiatry 151 (1994):1409-1416. In 1994, Harvard Medical School researchers reported that outcomes for schizophrenia patients in the U.S....

The Vermont Longitudinal Study & Correction of Seven Myths

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In a long-term study of schizophrenia patients released during the late 1950s and early 1960s from the back wards of Vermont State Hospital, Courtenay...

Schizophrenia: Manifestations, Incidence and Course in Different Cultures

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Schizophrenia: Manifestations, Incidence and Course in Different Cultures.Jablensky, A. Psychological Medicine, supplement 20 (1992):1-95. The second WHO study was called the Determinants of Outcome of Severe...

The International Pilot Study of Schizophrenia

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The International Pilot Study of Schizophrenia. Leff, J.Psychological Medicine, 22 (1992):131-145. The first World Health Organization study that compared schizophrenia outcomes in "developed" and "developing" countries...

Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated?

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Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated? Rappaport, M. International Pharmacopsychiatry, 13 (1978), 100-111. In this 1978 study,  Maurice Rappaport and his colleagues at...

The Treatment of Acute Schizophrenia Without Drugs

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The Treatment of Acute Schizophrenia Without Drugs. Carpenter, W. American Journal of Psychiatry, 134 (1977), 14-20. In this 1977 NIMH study, 49 schizophrenia patients placed into an experimental...

Comparing five-year outcomes in the pre-Thorazine era and the post-Thorazine era.

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Comparison of Two Five-Year Follow-up Studies.Bockoven, J. American Journal of Psychiatry, 132 (1975), 796-801. In this study, Boston psychiatrists Sanbourne Bockoven and Harry Solomon compared relapse rates...

Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication

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Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication. Prien, R. British Journal of Psychiatry, 115 (1968), 679-86. The critical finding of this NIMH study  was that...

Environmental Factors Drive Mania

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Harvard researchers investigated 6,214 cases of major depression for factors that would predict transition to bipolar disorder.  Clinical characteristics such as age of onset...

Brain Volume Recovers With Remission, Not With Medication

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In a prospective study of 28 outpatients with major depression, Canadian researchers investigated whether brain volume changes stabilized with antidepressant treatment and/or reversed with...

Ongoing Brain Changes With Antipsychotic Treatment

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Nancy Andreasen's 2003 study finding ongoing brain changes in persons with schizophrenia diagnoses, despite antipsychotic drug treatment. Article →             ...

Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated?

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1978 study of 80 young males diagnosed with acute schizophrenia, finding that "many unmedicated-while-in-hospital patients showed greater long-term improvement, less pathology at follow-up, fewer...

No Evidence for Antipsychotics’ Efficacy

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In a review of 681 studies comparing use of antipsychotic medication with placebo, milieu, or psychosocial treatment in first- or second-episode schizophrenia spectrum disorders,...

100% Of DSM Schizophrenia and Mood Disorder “Experts” Have Ties to Drug Companies

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A 2006 study in the journal Psychotherapy and Psychosomatics finds that 100% of schizophrenia and mood disorder experts and over 80% of other experts advising...

First Aid for Emotional Trauma

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Handout by Will Hall, offered on the Icarus Project website, on what emotional trauma is and how to work to heal it. Go to "First...

Positive Expectations for the Future Improves Quality of Life

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In a pilot study at Cedars-Sinai Medical Center in Los Angeles, researchers found that Future-Directed Therapy (FDT) improved quality of life and relieved depressive...

Dopamine Sensitivity a Result of Psychosis, Not a Risk Factor For It

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Researchers in the U.K. found that dopamine synthesis among twins with and without diagnoses of schizophrenia was unrelated to diagnosis, suggesting that excess dopamine...