Study Links SSRIs to Violent Crime in Youth

10
Individuals between the ages of 15 and 24 are more likely to commit a violent crime if they are taking an SSRI antidepressant than if they are not, according to new research out of Sweden. The study published in PLoS Medicine on Tuesday, suggests "warnings about the increased risk of violent behavior among young people taking SSRIs might be needed.”

“Antidepressant Paxil Is Unsafe for Teenagers, New Analysis Says”

1
In a major story, the New York Times presents the re-analysis by David Healy, Jon Jureidini, Mickey Nardo and others of Study 329, published in...

HuffPo Features 15 Part DocuSerial on Risperdal Corruption

4
Huffington Post and journalist Steve Brill have combined to launch a 15 part series about how Johnson & Johnson illegally violated FDA restrictions by pushing the antipsychotic drug, Risperdal, for use with adolescents and the elderly. The series, entitled “America’s Most Admired Lawbreaker,” launched yesterday and will include mixed media, videos, podcasts, source documents, as well as 15 written chapters. Click more for a synopsis of part 1.

Drug Treatment for Borderline Personality Disorder Not Supported By Evidence

23
New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”

Pfizer Drug Chantix Cited in Murder Plea

4
In exchange for pleading guilty to murder, a young soldier received a 45-year sentence with the possibility of parole. The plea resulted from evidence that Chantix, a smoking cessation drug manufactured by Pfizer, can increase hostility and agitation, according to the SunHerald. “Several experts provided some evidence that Chantix affected (the soldier’s) ability to appreciate the nature and quality or wrongfulness of his acts,” the SunHerald noted.

Pennsylvania Foster Kids Prescribed Too Many Psychotropic Drugs

9
Amid growing criticism about the over-prescription of psychotropic medication in foster care, Pennsylvania commissioned PolicyLab to conduct an analysis of the use of psychiatric drugs among all of the state’s Medicaid-enrolled children. The report, released in June, found that the rate of psychotropic prescriptions among youth in Medicaid and foster care was higher than previously reported.

Meta-Analysis Ties Gray Matter Loss to Antipsychotic Dose

8
Antipsychotics are currently the predominant treatment for individuals diagnosed with schizophrenia, but there is an accumulating body of research that links the use of these drugs to structural abnormalities in the brain. A recent meta-analysis suggests that gray matter loss in the brain may depend on the dose and class of the antipsychotic.

Antipsychotics Prescribed Off-Label for Challenging Behaviors

4
Antipsychotics are being prescribed to people who may have challenging behaviors but no mental disorder, according to new research published in this month’s issue of BMJ. “Excessive use of psychotropic drugs has individual and systemic implications,” the researchers write. “Antipsychotics, in particular, are associated with several adverse side effects that can impair quality of life and lead to deleterious health outcomes.”

“Antipsychotics May Be Pushed On Those with Intellectual Disabilities”

2
Psych Central covers findings published in BMJ revealing that many people in the U.K. with intellectual disabilities are being prescribed antipsychotic drugs. The study’s lead author comments: “People who show problem behaviors, along with older people with intellectual disability or those with co-existing autism or dementia, are significantly more likely to be given an antipsychotic drug, despite this being against clinical guidelines and risking possible harm.”

“Antipsychotic Use in Youth Without Psychosis: A Double-edged Sword”

11
This month’s issue of JAMA Psychiatry ran an editorial commenting on recent research revealing that the majority of youth prescribed antipsychotics have not been diagnosed with a mental disorder.

Members of FDA Advisory Committee Offer Perspectives on Flibanserin Approval in JAMA

5
In the September issue of The Journal of the American Medical Association (JAMA) three FDA advisory committee members describe the convergence of factors that made the committee’s recommendation to approve flibanserin especially challenging and politically charged.

“New Depression Meds Not Effective Generally, But Drug Companies Insist Otherwise: Study”

2
The International Business Times covers a new study showing “trials for new antidepressant medications may not be applicable to the population at large.” “The finding, published in the Mayo Clinic Proceedings, shows recent trials are less generalizable than the prior studies, as researchers excluded most depressed patients from drug company-sponsored treatment studies.”

FDA: Antidepressant Trials Have Not Adequately Reported Sexual Dysfunction Side Effects

12
US Food and Drug Administration scientists want to better evaluate side effects of sexual dysfunction associated with antidepressant drugs.

Many Physicians Don’t Understand Key Facts about Prescription Opioid Addictions

11
A Johns Hopkins Bloomberg School of Public Health survey of 1000 US primary care physicians found that many do not understand basic medical facts about the addictive nature of the opioids they are prescribing.

Antidepressants Worsen Rapid Cycling in Bipolar Depression

10
-SSRI antidepressant medications contribute to a significant worsening of emotional "rapid cycling" in patients diagnosed with bipolar disorder.

Slew of New Studies Spot Links Between Psychiatric Medications and Bone Loss, Fractures

7
Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

Antidepressant-linked Suicide Data Doctored In Seminal Study

26
Several years after the information was first revealed, a published study has shown how an influential NIMH study doctored the real data about antidepressants and suicidal events in youth.

Clozapine-induced Stuttering Affects 1% Of Patients

3
A team of psychiatrists reviewed 654 cases in West Ireland to find that nearly 1% of all patients taking the antipsychotic clozapine had experienced clozapine-induced stuttering.

Antipsychotic Dose Reduction Linked To Long-term Improvements In First-Episode Schizophrenia Patients

12
Careful reductions in dosage levels of antipsychotic medications over time improved long-term rates of recovery and functional remission in patients diagnosed with a first-episode psychosis.

No Treatments Have “Clinically Meaningful” Impacts On Negative Symptoms of Schizophrenia

14
While most treatments have had "statistically significant" success in clinical trials, no common psychiatric or psychological treatments improve the negative symptoms of schizophrenia at levels that are "clinically meaningful."

Pennsylvania Latest State To Try To Curb Psychotropic Prescribing To Foster Children

4
Foster children in Pennsylvania are being given psychotropic drugs by physicians at rates that are "disturbing" and "unacceptable," according to the state's Department of Human Services.

One-quarter of Ohio-area Children With Down Syndrome Are Being Prescribed Psychotropics

4
The odds of a child with Downs Syndrome being on a psychotropic medication increase steadily with age.

Antidepressants During Pregnancy Do Not Appear To Reduce Relapses And Hospitalizations

5
Continuing to take antidepressants during pregnancy was associated with higher rates of depressive relapses and hospitalizations than discontinuing.

Not an Onion Study: Underpowered Analysis Of Poor Quality Data Finds Antipsychotics Actually Aren’t...

12
University of Groningen researchers analyzed only small, short-term clinical trials of generally poor quality to determine that antipsychotics are not linked to increased risk of death in elderly people with dementia.

Many Teens Start Misusing Stimulants By Age 13

1
An equal percentage of young people will start misusing ADHD-related and other stimulant drugs for the first time at age 13 as will start at age 20.