Peer-Support Groups Were Right, Guidelines Were Wrong: Dr. Mark Horowitz on Tapering Off Antidepressants

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In an interview with MIA, Dr. Horowitz discusses his recent article on why tapering off antidepressants can take months or even years.

Is Long-term Use of Benzodiazepines a Risk for Cancer?

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A large study of the population in Taiwan reveals that long-term use of benzodiazepine drugs, commonly prescribed for anxiety, significantly increases the risk for brain, colorectal, and lung cancers. The research, published open-access in the journal Medicine, also identifies the types of benzodiazepines that carry the greatest cancer risk.

Transcranial Magnetic Stimulation No Better Than Placebo for Treatment-Resistant Depression

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A new study in JAMA Psychiatry found that transcranial magnetic stimulation was no better than placebo for treatment-resistant depression.

New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”

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A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”

Cognitive Impairment from Long-Term Benzodiazepine Use Remains Even After Drug Withdrawal

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Long-term benzodiazepine use shown to effect cognitive function during current use and for years after drug discontinuation.

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

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A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Initial Trial of Ayahuasca for Depression Shows Promising Results

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Ayahuasca found to be effective in treating moderate to severe depression in low-income population.

Psychotropic Medications Serve as Powerful Tools for U.S. Military, Imperialism

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Ethnographic research sheds light on extensive psychopharmaceutical use by soldiers in post 9/11 U.S. wars.

Mindfulness Pain Relief Distinct from Placebo Effect

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A new study demonstrates that the practice of mindfulness may ease pain in a way that is mechanistically distinct from the placebo effect. Research, published in the Journal of Neuroscience, found that mindfulness meditation not only outperformed placebo and fake meditation for pain relief but that it also activated different brain regions than the placebo treatments.

Review Explores First-Person Experiences of People Taking Antipsychotics

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A new systematic review finds that patients report reduced symptoms but also loss of self and agency while taking antipsychotics.

Vitamin B6 Effective in Reducing Antipsychotic Induced Akathisia

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A recent RCT showed that vitamin B6 is as effective as propranolol for the treatment of akathisia.

Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics

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Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

Most People with Common ‘Mental Disorders’ Get Better Without Treatment, Study Finds

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A new study suggests that most people diagnosed with depressive, anxiety, and substance abuse disorders recover without treatment within a year of diagnosis. “This...

Researcher Acknowledges His Mistakes in Understanding Schizophrenia

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Sir Robin Murray, a professor at the Institute of Psychiatry, Psychology, and Neuroscience in London, states that he ignored social factors that contribute to ‘schizophrenia’ for too long. He also reports that he neglected the negative effects antipsychotic medication has on the brain.

Antidepressants Increase Risk of Death, Study Finds

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Antidepressants are commonly considered safe and effective treatments. However, research has questioned their efficacy, and now, their safety.

Very Slow Tapering Best For Antidepressant Withdrawal

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A new article in Lancet Psychiatry finds that slower tapering of SSRIs is better for preventing antidepressant withdrawal effects.

Olanzapine Can Cause Serious Skin Reaction, FDA Warns

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The US FDA has issued a new warning for the atypical antipsychotic Olanzapine, also known by the brand names Zyprexa and Symbyax. The agency...

Therapy Recommended As First Line Treatment for Depression

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Following an extensive systematic review of treatments for major depression, the American College of Physicians (ACP) issued a recommendation to clinicians suggesting cognitive behavioral therapy (CBT) as a first-line treatment for major depressive disorder along with second-generation antidepressants. The results of the review revealed that CBT and antidepressants have similar levels of effectiveness but that antidepressants present serious side-effects and higher relapse rates.

Researchers Set the Record Straight on Controversial Zoloft Study

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An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).

Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorder

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Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.

Garbage In–Garbage Out: Systematic Reviews and Meta-Analyses can tell us a Flawed Story

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Well known Stanford University researcher John Ioannidis published a new paper this week criticizing the use and production of systematic reviews and meta-analyses, often...

Scientists Clarify Risks of Augmenting with Antipsychotic Medications for Depression

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The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.

Long-term Usage of ADHD Drugs Linked to Growth Suppression

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Findings suggest that treatment not only fails to reduce the severity of “ADHD” symptoms in adulthood but is associated with decreased height.

Researchers Find Paroxetine Harms Developing Brain

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Researchers at Johns Hopkins test paroxetine on developing brain cells and discover numerous neurotoxic effects.

Antidepressant Use Leads to Worse Long Term Outcomes, Study Finds

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Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.