Antipsychotics Again Strongly Linked to Falls and Fractures

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Three independent studies in two journals reported strong links between antipsychotics and falls and fractures.

Different Antipsychotics Have Different Effects on Brain Volume

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First generation antipsychotics seem to cause general brain volume loss, while second generation antipsychotics seem to both increase and decrease the thickness of different parts of the brain.

Lower Education Linked to Higher Antipsychotic Use in Swedish Elderly

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Elderly people in Sweden are five times more likely to be taking antipsychotics if they have a diagnosis of dementia, according to research published in Acta Psychiatrica Scandinavica. And among those people with dementia, the lower their education the higher the likelihood they’re taking antipsychotics.

More than Half of UK Antipsychotic Prescribing is Not for Authorized Conditions

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More than half of the prescriptions for antipsychotic drugs in the UK are being issued "off-label" to treat conditions other than those for which the drugs are approved, according to a large study published in the British Medical Journal Open. Researchers also found significantly higher levels of prescribing of the medications to poorer people.

Sexual Dysfunction from Antipsychotics Common — But Poorly Monitored by Physicians

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Describing the prevalence and management of adverse effects from antipsychotics as "a neglected area" of study, a team of researchers from the UK has published a systematic review in the Journal of Psychopharmacology. They aimed to identify the prevalence of, and management strategies for nine categories of adverse effects, including sedation, weight gain, metabolic syndrome, sexual dysfunction and cardiovascular effects.

Antipsychotic Drug Associated with Potentially Fatal Skin Rash

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The US Food and Drug Administration is warning the public that the antipsychotic medication ziprasidone "is associated with a rare but serious skin reaction...

Psychiatrists’ Prescriptions for First-time Psychosis Often Don’t Follow Guidelines

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"Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment," states a National Institute of Mental Health...

Psychiatric Medication Use Associated with Triple the Risk of Stroke

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Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

Common Parkinson’s Drugs Linked to Pathological Gambling and Hypersexuality

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"Pathological gambling, hypersexuality, compulsive shopping and other impulse control disorders were associated with the use of dopamine receptor agonists, often prescribed for Parkinson’s disease,...

Researchers Struggle as Placebos Becoming More Effective & Antipsychotics Losing Power

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Since the 1960s, the positive response rates to antipsychotic medications have been dropping steadily, according to a meta-analysis published in JAMA Psychiatry by Columbia...

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

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It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...

Antipsychotic Medications Are Causing Obsessive Compulsive Disorders

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Common second-generation antipsychotic medications are causing symptoms of obsessive-compulsive disorder to emerge in many people who previously only had schizophrenia symptoms, according to a...

Smoking Cessation and Psychiatric Drugs Cause the Most Suicidal and Homicidal Reactions

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The popular smoking cessation drug Chantix is the medication that most frequently makes people feel suicidal or homicidal, according to figures gathered by the...

Alberta Long-term Care Homes Reduce Antipsychotic Use by 50%

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The provincial government health service of Alberta, Canada recently concluded a successful pilot project that reduced the use of antipsychotic medications for patients with...

Less-impaired Youth Using Antipsychotics with Other Medications More Often

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Use of second-generation antipsychotics (SGA) alongside other medications is growing rapidly among youth who are less impaired, according to a study published online in...

Antipsychotic Risperidone Raises Risk of Male Breast Enlargement

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Taking the antipsychotic medication risperidone significantly increases men's chances of developing gynecomastia, or breast enlargement, according to a study by University of British Columbia...

More Time in Foster Care Linked to More Psychotropic Medicating

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Children as young as four in foster care are taking three or more psychotropic medications, and the length of time that children aged six...

Antipsychotics Linked to Cognitive & Memory Impairments

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Finnish reseachers report in Schizophrenia Research that antipsychotic use is associated with cognitive and memory impairments. The University of Oulu team studied forty people...

More Evidence Antipsychotics Reduce Brain Volume

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People diagnosed with schizophrenia experience reductions in brain volume that increase over time, and the amount of those reductions increases in proportion to the...

Glucose Metabolism “Derangements” from Second Generation Antipsychotics Clarified

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New Zealand and Chinese investigators believe they have clarified the mechanisms by which second generation antipsychotics cause serious "derangements" in glucose metabolism in the...

Adverse Reactions to Psychiatric Medications Hospitalize 17,000 Annually

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Nearly 90,000 American adults are going to emergency rooms every year in response to adverse events from psychiatric medications, according to a study in...

Antipsychotics During Pregnancy Linked to Infant Problems

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“Live, healthy babies are the most common outcome following the use of antipsychotic medication in pregnancy,” conclude Australian researchers in a study that was...

20-Year Data Show Antipsychotics Do Not Reduce Psychosis

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Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

A History of Rapid Tranquilization

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A paper by Joanna Moncrieff and Laura Allison in the journal History of Psychiatry reviews "the theory and practice of emergency sedation for behavioural...

Antipsychotics Ineffective Against Cocaine, Stimulant Addictions

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Although cocaine and psychostimulant dependence are thought to be related to increased dopamine release, research from Tokyo and Long Island finds that the effect...