Antipsychotics Ineffective Against Cocaine, Stimulant Addictions

2
Although cocaine and psychostimulant dependence are thought to be related to increased dopamine release, research from Tokyo and Long Island finds that the effect...

Drug Treatment for Borderline Personality Disorder Not Supported By Evidence

23
New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”

How Exercise Can Help With First Episode Psychosis

8
New study examines the experiences of people utilizing an exercise program following a first-episode psychosis.

Off-Label Antipsychotic Use Among Children Soaring

2
Researchers from Philadelphia and Baltimore find, in a study of Medicaid records for 50 states and the District of Columbia, that antipsychotic prescribing to...

Researchers Test Harms and Benefits of Long Term Antipsychotic Use

28
Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

Study Reduces Over-prescription of Antipsychotics in Older Adults

8
New intervention shows promise in reducing over-prescription of off-label antipsychotics in older adults.

“Antipsychotic Use in Youth Without Psychosis: A Double-edged Sword”

11
This month’s issue of JAMA Psychiatry ran an editorial commenting on recent research revealing that the majority of youth prescribed antipsychotics have not been diagnosed with a mental disorder.

Prenatal Antipsychotic Exposure Causes Neuromotor Deficits

2
Researchers studying 309 6-month-olds at Emory University's Infant Development Laboratory found that infants prenatally exposed to antipsychotics showed significantly lower scores on a standardized...

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

62
People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.
Illustration of man sitting on a red and white pill. He holds his head with pain symbols in the air above him.

Adding Antipsychotics Worsens Outcomes in Psychotic Depression

15
Outcomes were worse for all, with young people on combination therapy twice as likely to experience rehospitalization or death by suicide than those on antidepressants alone.

Antipsychotics Associated with White-Matter Reduction

6
Researchers in China find an acute reduction in white matter in the frontal lobe following six weeks of antipsychotic treatment for "first-episode schizophrenia". Results...

Some Avoid Antipsychotics Because They Value Psychosis

0
Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...

Review Links Antipsychotics with Risk for Heart Attacks

6
A systematic review published this week in the British Journal of Clinical Pharmacology found that patients taking antipsychotic drugs were at nearly twice the risk...

Antipsychotics During Pregnancy Raise Diabetes Risk

0
Swedish researchers find, in a study of all women giving birth in Sweden from July 1, 2005 through December 31, 2009 that those taking...

Increasing Use of Antipsychotics for Disruptive Behavior in Children

5
Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...

Antipsychotics Often Prescribed Without Informed Consent

27
New research reveals that patients are often not given fully informed consent before being prescribed antipsychotics.

Four Leading Antipsychotics Aren’t Safe or Effective in Older Adults

14
A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...

Increased Risk of Movement Disorders From Antipsychotics in Persons with Intellectual Disabilities

4
Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.

Abilify Can Worsen Psychosis & Aggression

0
In a systematic literature review, researchers from Canada and Japan found that the antipsychotic aripiprazole (Abilify) was significantly and causally related to increased increased...

Antipsychotics Increase Risk of Heart Attack in the Elderly

0
In a study of 10,969 older patients treated with antipsychotics in Quebec, Canada, researchers found a 2.19 times greater risk of heart attack in...

Relapse in Antipsychotic Drug Trials is Poorly Defined

8
There is a lack of consensus in the definition of ‘relapse’ across randomized controlled trials of antipsychotic maintenance treatment for schizophrenia and psychosis.

Disconnect Between Antipsychotic Prescribing and Metabolic Screening

1
Despite American Diabetes Association and APA recommendations of glucose and lipid testing for all patients started on antipsychotics, there is a disconnect between prescribing...

Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs

15
The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

Assessing Increased Mortality Risks of Antipsychotics and Mood Stabilizers in Dementia

0
An article in January's American Journal of Psychiatry weighs the relative risk of mortality associated with various antipsychotics and mood stabilizers used in the treatment of...

Identifying Psychiatric Drugs Leading to Emergency Room Visits

14
More than ten-percent of adults in the United States are currently prescribed at least one psychiatric medication but there is currently a lack of research on the prevalence of adverse drug events (ADEs) associated with these prescriptions outside of clinical trials.