Wednesday, September 30, 2020

Psychiatric Medication Use Associated with Triple the Risk of Stroke

Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

Two-Thirds of Schizophrenia Patients Do Not Remit on Antipsychotics

A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.

More Time in Foster Care Linked to More Psychotropic Medicating

Children as young as four in foster care are taking three or more psychotropic medications, and the length of time that children aged six...

Antipsychotics Associated with High Risk of Death in Children

A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Does Longer Duration of Untreated Psychosis Cause Worse Outcomes?

New research counters the long-held assumption that a longer duration of untreated psychosis is associated with worse outcomes.

Contribution of Antipsychotics to Suicidality and Depression

Peter Lehmann reviews the contribution of antipsychotics to suicide and depression in schizophrenia in the current International Journal of Psychotherapy.  Publications about the intrinsic effects of...

Rise of Antipsychotics in Children

Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...

Atypicals Associated with Diabetes in Adults Without Schizophrenia or Bipolar Diagnoses

Writing in Evidence Based Mental Health, researchers from Harvard Medical School and Massachusetts General Hospital found that use of medication for diabetes was significantly...

Lower Education Linked to Higher Antipsychotic Use in Swedish Elderly

Elderly people in Sweden are five times more likely to be taking antipsychotics if they have a diagnosis of dementia, according to research published in Acta Psychiatrica Scandinavica. And among those people with dementia, the lower their education the higher the likelihood they’re taking antipsychotics.

Little Evidence on Effectiveness or Risks of Antipsychotics in Young People

Evidence-Based Mental Health reviews studies (from 1987 to 2011) of antipsychotics in people under 24 years old, finding weak evidence on comparative effectiveness of antipsychotics or...

Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs

The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.

Antipsychotics Triple the Risk of Diabetes in Children and Youth

Researchers from Vanderbilt and Columbia Universities and the FDA find that, through a retrospective cohort study of 28,858 patients of the Tennessee Medicaid program...

Risk of Death in the Elderly Trebled With Antipsychotics

In a nine-year study of all 2,224 residents of Leppävirta, Finland who were 65 years old or older, researchers found that the 332 residents...

Scant Evidence for Combining Antipsychotics

Researchers in Barcelona, Spain retrospectively reviewed the use of antipsychotics in 117,811 patients, of whom 9,855 were given combinations of antipsychotics and 13,763 were...

For People “At Risk for Psychosis,” Antipsychotics Associated with Worse Outcomes

Researchers studied whether antipsychotics could prevent transition to full psychosis and found that the drugs worsened outcomes.

Adverse Reactions to Psychiatric Medications Hospitalize 17,000 Annually

Nearly 90,000 American adults are going to emergency rooms every year in response to adverse events from psychiatric medications, according to a study in...

Abilify Can Worsen Psychosis & Aggression

In a systematic literature review, researchers from Canada and Japan found that the antipsychotic aripiprazole (Abilify) was significantly and causally related to increased increased...

Withdrawal from Antipsychotics

A review of the scientific literature related to the withdrawal of antipsychotics: animal studies, withdrawal symptoms, tapering success rates, and consumer accounts of discontinuation.

Some Avoid Antipsychotics Because They Value Psychosis

Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...

The Case Against Antipsychotics

This review of the scientific literature, stretching across six decades, makes the case that antipsychotics, over the long-term, do more harm than good. The drugs lower recovery rates and worsen functional outcomes over longer periods of time.

2nd-Generation Antipsychotics Cause Extrapyramidal Side Effects as Much as 1st-Generation

According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...

Nurses Confront the Myths of Psychiatric Drugs

The July issue of Nursing Ethics takes on the myths of psychiatric drugs, saying that "psychiatric drugs are used only to control ‘patient’ behaviour...

More Evidence That Antipsychotics Shrink the Brain

European researchers who reviewed 43 imaging studies of first-episode psychosis found evidence that antipsychotics cause a decrease in gray matter volumes in the brain....

Review Finds FDA Approval of Digital Antipsychotic Misguided

The approval of the digital antipsychotic may open the door for more pharmaceutical company profits without evidence of benefits to patients.

Antipsychotic Use in Nursing Homes Causing Many Adverse Effects in Elderly

A literature review found that the extensive off-label use of antipsychotic medications in nursing homes is causing many adverse effects and providing limited benefits.

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