Antipsychotics During Pregnancy Raise Diabetes Risk

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Swedish researchers find, in a study of all women giving birth in Sweden from July 1, 2005 through December 31, 2009 that those taking...

New Research Suggests Brain Abnormalities in ‘Schizophrenia’ May Result From Antipsychotics

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Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

Antipsychotics Increase Risk of Dementia; New Research Illuminates Why

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In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

Antipsychotics Worsen Cognitive Functioning in First-Episode Psychosis

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Withholding antipsychotics may be beneficial for memory, the researchers write.

20-Year Data Show Antipsychotics Do Not Reduce Psychosis

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Martin Harrow's study tracing the effects of antipsychotics on 139 schizophrenia (SZ) and mood-disordered patients over 20 years, just published in Psychological Medicine, finds...

Major Risks from Drug Interactions in Common Psychiatric Polypharmacy

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It is very common for psychiatric patients, especially those diagnosed with schizophrenia, to be prescribed two or more psychiatric medications at once, and this...
Doctor and patient

Barriers to Shared Decision Making in the Prescription of Antipsychotics

Researchers push for a renewed focus on true shared decision-making for patients diagnosed with psychosis.

Seroquel Abuse Rising, Along With Ambulance Calls

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Australian researchers have uncovered an alarming increase of Seroquel-related ambulances calls. Rising prescriptions of of the drug along with its developing use as a drug...

2nd-Generation Antipsychotics Cause Extrapyramidal Side Effects as Much as 1st-Generation

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According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...

Alarm About Antipsychotics as Sleep Aids

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Canadian sleep researchers, writing in The Lancet, warn that weight gain, lipid and glucose dysregulation, restless leg syndrome, sleep-walking and eating while asleep, and...

Anticholinergic Medications Linked to Dementia Similar to Early Alzheimer’s

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A new study, published in the Journal of Clinical Psychiatry, investigates the effects of anticholinergic medications, such as antidepressants and antipsychotics, on cognition in older adults diagnosed with schizophrenia.

Antipsychotics Linked to Cognitive & Memory Impairments

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Finnish reseachers report in Schizophrenia Research that antipsychotic use is associated with cognitive and memory impairments. The University of Oulu team studied forty people...

Antipsychotics Aren’t Helpful to Children

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Researchers from London, writing in European Psychiatry, reviewed "all RCTs involving children and young people with a diagnosis of childhood onset schizophrenia comparing any...

Increased Risk of Movement Disorders From Antipsychotics in Persons with Intellectual Disabilities

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Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.

An FDA Whistleblower’s Documents: Commerce, Corruption, and Death

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In 2008, a reviewer of psychiatric drugs at the FDA, Ron Kavanagh, complained to Congress that the FDA was approving a new antipsychotic that was ineffective and yet had adverse effects that increased the risk of death. Twelve years later, a review of the whistleblower documents reveal an FDA approval process that can lead to the marketing of drugs sure to harm public health.

NMS in 2nd Gen. Antipsychotics: Similar, But Younger

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A study released online today by the British Journal of Psychiatry shows that the clinical profile of neuroleptic malignant syndrome (NMS) is similar in 1st- v....

Psychiatrists’ Prescriptions for First-time Psychosis Often Don’t Follow Guidelines

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"Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment," states a National Institute of Mental Health...

Despite Safety Risks, Prescribers Receive Little Guidance of Monitoring Antipsychotic Clozapine

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A new review finds a lack of available guidance on how to effectively monitor adverse effects of antipsychotic drug clozapine.

A Tale of Two Studies

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With increasing evidence that psychiatric drugs do more harm than good over the long term, the field of psychiatry often seems focused on sifting through the mounds of research data it has collected, eager to at last sit up and cry, here’s a shiny speck of gold! Our drugs do work! One recently published study on withdrawal of antipsychotics tells of long-term benefits. A second tells of long-term harm. Which one is convincing?

Reducing Antipsychotic Use May Improve Health for People with Mental Health Diagnoses

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A new study offers radical solutions for improving the cardiovascular health of people with mental health diagnoses: reducing antipsychotic prescriptions..

Drug Treatment for Borderline Personality Disorder Not Supported By Evidence

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New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”

Case Studies Reveal Patient Empowerment Through Tapering Antipsychotics

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A new study shows how different patients respond to tapering antipsychotic medication under expert guidance, highlighting personal empowerment and the complexities of withdrawal.

PTSD and Psychiatric Medication Linked to Dementia in Older Veterans

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Veterans diagnosed with PTSD and taking SSRIs, novel antidepressants, or atypical antipsychotics are more likely to develop dementia.

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

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People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.

More Evidence That Antipsychotics Shrink the Brain

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European researchers who reviewed 43 imaging studies of first-episode psychosis found evidence that antipsychotics cause a decrease in gray matter volumes in the brain....