Tuesday, September 17, 2019

How Exercise Can Help With First Episode Psychosis

New study examines the experiences of people utilizing an exercise program following a first-episode psychosis.

Review Finds FDA Approval of Digital Antipsychotic Misguided

The approval of the digital antipsychotic may open the door for more pharmaceutical company profits without evidence of benefits to patients.
Yellow sign reading "Cognitive Hazard"

Discontinuation of Antipsychotics Improves Cognitive Functioning

A study, recently published in Psychological Medicine, examined the cognitive functioning of individuals with schizophrenia who discontinued antipsychotics, and those who maintained their antipsychotic...

Anticholinergic Psychiatric Drugs Linked to a 50% Increase in Dementia

People who take anticholinergic drugs, such as antidepressants and antipsychotics, are at a 50% higher risk of dementia.

Service-Users See Long-Term Antipsychotic Use as Compromising Recovery, Review Finds

A new meta-review examines the experiences of antipsychotic drugs use among people diagnosed with a psychotic disorder.

Better Outcomes Off Medication for Those Recovered from First-Episode Schizophrenia

A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioning—and reached full recovery more quickly.

Antipsychotics Associated with High Risk of Death in Children

A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Claims That Long-term Antipsychotic Use Leads to Better Outcomes are Misleading, Researchers Argue

Researchers reveal the limitations and misleading interpretations of two recent studies that claim to demonstrate that long-term antipsychotic use leads to better outcomes.

Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics

Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

Two-Thirds of Schizophrenia Patients Do Not Remit on Antipsychotics

A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.

New Review of Antipsychotics for Schizophrenia Questions Evidence for Long Term Use

A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

Call to Monitor Adverse Effects of Antipsychotics in Youth

Researchers point to the risks of using antipsychotics with youth and caution against the practice.

New Research Suggests Brain Abnormalities in ‘Schizophrenia’ May Result From Antipsychotics

Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

A Tale of Two Studies

With increasing evidence that psychiatric drugs do more harm than good over the long term, the field of psychiatry often seems focused on sifting through the mounds of research data it has collected, eager to at last sit up and cry, here’s a shiny speck of gold! Our drugs do work! One recently published study on withdrawal of antipsychotics tells of long-term benefits. A second tells of long-term harm. Which one is convincing?

Reducing Antipsychotic Use May Improve Health for People with Mental Health Diagnoses

A new study offers radical solutions for improving the cardiovascular health of people with mental health diagnoses: reducing antipsychotic prescriptions..

Anticholinergic Medications Linked to Dementia Similar to Early Alzheimer’s

A new study, published in the Journal of Clinical Psychiatry, investigates the effects of anticholinergic medications, such as antidepressants and antipsychotics, on cognition in older adults diagnosed with schizophrenia.

Scientists Clarify Risks of Augmenting with Antipsychotic Medications for Depression

The researchers found that while antipsychotic drugs may be slightly more effective than alternative antidepressants, they come with a much higher side effect burden.

Patients on Antipsychotics at High Risk for Cardiovascular Issues, Study Finds

Antipsychotics present a known risk for major side effects. A new study suggests that certain antipsychotics may present a greater risk for cardiovascular disease than others.

Inappropriate Use of Antipsychotics on Adults with Intellectual and Developmental Disabilities

One-third of adults with an intellectual or developmental disability are dispensed antipsychotics, despite having no existing psychiatric diagnosis.

Increased Risk of Movement Disorders From Antipsychotics in Persons with Intellectual Disabilities

Large cohort study demonstrates that those with an intellectual disability are at an increased risk for movement disorder side effects of antipsychotics.

Patients With Schizophrenia Show Better Work Functioning Off Antipsychotics

20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.

In Chronic Patients, Antipsychotics Have Limited Efficacy in Reducing Symptoms

A large review and meta-analysis of 167 studies across 60 years dissects placebo-controlled randomized controlled trials of antipsychotic drugs.

Half of First-Episode Patients Respond to Antipsychotics

No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

Large Study Confirms Elevated Risk of Diabetes When Prescribed Antipsychotics

A large longitudinal study finds once more that being prescribed antipsychotics significantly increases the risk of diabetes.

Study Shows Clozapine Can Result in Serious Gastrointestinal Complications

A large observational study published in CNS Drugs sheds light on serious adverse effects of the ‘gold standard’ antipsychotic Clozapine.

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