Abilify Can Worsen Psychosis & Aggression

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In a systematic literature review, researchers from Canada and Japan found that the antipsychotic aripiprazole (Abilify) was significantly and causally related to increased increased...

Long-term Outcomes Better for Those Who Stop Taking Antipsychotics

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Research undermines the prolonged use of antipsychotics in schizophrenia treatment, suggesting improved social functioning and quality of life with discontinuation.
Young man refusing to take prescribed pills in clinic

Antipsychotics Lead to Worse Outcomes in First-Episode Psychosis

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Those who did not get antipsychotics in the first month were almost twice as likely to be in recovery after five years.

Randomized Controlled Trial Confirms That Antipsychotics Damage the Brain

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A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.

Wunderink: Antipsychotics Can Be Tapered Safely Without Increasing Relapse Risk

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Tapering antipsychotics slowly and with supported decision-making may improve care for patients with psychosis.

When Medication Changes More Than Symptoms: Antipsychotics’ Effect on Identity

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Recent research reveals how antipsychotic medications can significantly impact users' identity and self-image, challenging existing clinical approaches.

Case Studies Reveal Patient Empowerment Through Tapering Antipsychotics

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A new study shows how different patients respond to tapering antipsychotic medication under expert guidance, highlighting personal empowerment and the complexities of withdrawal.

Study Highlights Difficulty of Antipsychotic Withdrawal

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New research finds insomnia, anxiety, and depression are common symptoms of antipsychotic withdrawal, highlighting difficulties of discontinuation.

Study Links Prenatal Antipsychotic Exposure to Developmental Delays and ADHD

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A comprehensive review indicates that children exposed to antipsychotics in the womb face an increased risk of ADHD and developmental delays.

Despite Safety Risks, Prescribers Receive Little Guidance of Monitoring Antipsychotic Clozapine

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A new review finds a lack of available guidance on how to effectively monitor adverse effects of antipsychotic drug clozapine.

An FDA Whistleblower’s Documents: Commerce, Corruption, and Death

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In 2008, a reviewer of psychiatric drugs at the FDA, Ron Kavanagh, complained to Congress that the FDA was approving a new antipsychotic that was ineffective and yet had adverse effects that increased the risk of death. Twelve years later, a review of the whistleblower documents reveal an FDA approval process that can lead to the marketing of drugs sure to harm public health.

Contribution of Antipsychotics to Suicidality and Depression

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Peter Lehmann reviews the contribution of antipsychotics to suicide and depression in schizophrenia in the current International Journal of Psychotherapy.  Publications about the intrinsic effects of...

A Short History of Tardive Dyskinesia: 65 Years of Drug-Induced Brain Damage That Rolls...

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Psychiatry has long turned a blind eye to the full scope of harm associated with TD. New TD drugs "work" by further impairing brain function.

Do Antipsychotics Protect Against Early Death? A Review of the Evidence

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Psychiatry is now claiming that research has shown that antipsychotics reduce mortality among the seriously mentally ill. A critical review of the literature reveals that this claim is best described as the the field's latest "delusion" about the merits of these drugs.

Recovery Rate Six Times Higher For Those Who Stop Antipsychotics Within Two Years

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People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.
Illustration of man sitting on a red and white pill. He holds his head with pain symbols in the air above him.

Adding Antipsychotics Worsens Outcomes in Psychotic Depression

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Outcomes were worse for all, with young people on combination therapy twice as likely to experience rehospitalization or death by suicide than those on antidepressants alone.

Psychiatry Defends Its Antipsychotics: A Case Study of Institutional Corruption

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Jeffrey LIeberman and colleagues have published a paper in the American Journal of Psychiatry stating that there is no evidence that psychiatric drugs cause long-term harm, and that the evidence shows that these drugs provide a great benefit to patients. A close examination of their review reveals that it is a classic example of institutional corruption, which was meant to protect guild interests.

Antipsychotics Increase Risk of Dementia; New Research Illuminates Why

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In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

For People “At Risk for Psychosis,” Antipsychotics Associated with Worse Outcomes

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Researchers studied whether antipsychotics could prevent transition to full psychosis and found that the drugs worsened outcomes.

The Case Against Antipsychotics

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This review of the scientific literature, stretching across six decades, makes the case that antipsychotics, over the long-term, do more harm than good. The drugs lower recovery rates and worsen functional outcomes over longer periods of time.

New Research Suggests Brain Abnormalities in ‘Schizophrenia’ May Result From Antipsychotics

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Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

Infants Exposed to Psychotropic Drugs During Pregnancy At Risk

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New research published in the July issue of The Journal of Clinical Psychiatry found that the use of mood stabilizers, antipsychotics, antidepressants, and hypnotics during pregnancy is associated with increased health risks to the infant.
Letter blocks spelling "CANCER" and spilled pills in various colors on a white background

Cancer Risk Higher for Those on Clozapine

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The antipsychotic clozapine, considered the “gold-standard” treatment for psychosis, was found to increase the risk of blood and lymph system cancers.

Very Slow Taper Best for Antipsychotic Discontinuation

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An article in JAMA Psychiatry advises very slow tapering for best results when discontinuing antipsychotic drugs.

Anticholinergic Psychiatric Drugs Linked to a 50% Increase in Dementia

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People who take anticholinergic drugs, such as antidepressants and antipsychotics, are at a 50% higher risk of dementia.