APA Recommends Reducing Antipsychotics for Children and Elderly Without Psychosis

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The American Psychiatric Association, as part of the American Board of Internal Medicine's "Choosing Wisely" initiative, released new practice guidelines yesterday that advise against...

“Should We Stop Using Antipsychotic Medication?”

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In a recent interview, Nancy Andreasen, former editor-in-chief of the American Journal of Psychiatry, reaffirmed her earlier findings that antipsychotics shrink brain tissue. "We spent a couple...

Cognitive Function Improved by Reducing Antipsychotics

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A 28-week randomized controlled study by researchers in Japan, Canada and the United States finds that a 50% reduction of risperidone or olanzapine significantly...

Antipsychotics Triple the Risk of Diabetes in Children and Youth

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Researchers from Vanderbilt and Columbia Universities and the FDA find that, through a retrospective cohort study of 28,858 patients of the Tennessee Medicaid program...

Reduction/Discontinuation of Antipsychotics Produces Higher Long-Term Recovery

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A study published today in the American Medical Association's journal JAMA Psychiatry reports that patients whose antipsychotic treatment was reduced or discontinued (DR) experienced a recovery...

Antipsychotics and Drug Addiction

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Dopamine supersensitivity as a result of sustained antipsychotic treatment can lead to compulsive drug seeking and drug-taking behavior, according to the theory offered by...

Abilify Can Worsen Psychosis & Aggression

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In a systematic literature review, researchers from Canada and Japan found that the antipsychotic aripiprazole (Abilify) was significantly and causally related to increased increased...

Osteoporosis Associated with Antipsychotic Treatment

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Chinese researchers find, in a literature review for the International Journal of Endocrinology find an increased rate of osteoporosis among people with a schizophrenia...

Elderly With Dementia can be Withdrawn From Antipsychotics

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The Cochrane Library reports that "many older people with Alzheimer's dementia and NPS (neuropsychiatric symptoms) can be withdrawn from chronic antipsychotic medication without detrimental effects...

Antipsychotics for Poor Kids Soar, Mostly for Behavior Problems

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Cross-sectional analysis by the University of Maryland and Johns Hopkins University of 456,315 youths enrolled in Medicaid between 1997 and 2006 finds that the...

Antipsychotics for Depression: Added Risk for Little Benefit

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A review of research on antipsychotic medications as an adjunctive treatment for depression published this week in PLoS Medicine finds that the widespread practice...

Antipsychotics do not Result in Neurocognitive Improvement

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Researchers in London and Spain, in a prospective, randomized, study of long-term (3 year) effects of first- and second-generation antipsychotics on neurocognition in 79...

Antipsychotics Associated with White-Matter Reduction

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Researchers in China find an acute reduction in white matter in the frontal lobe following six weeks of antipsychotic treatment for "first-episode schizophrenia". Results...

Antipsychotics are Common for the Mechanically Ventilated

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Annals of Pharmacotherapy reports in a study of patients undergoing mechanical ventilation that 39% were given antipsychotic medication to prevent or treat delirium despite...

Increasing Use of Antipsychotics for Disruptive Behavior in Children

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Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...

Majority of Anorexia Patients are Prescribed Psychotropics Despite Lack of Data

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Research from the medical schools of Harvard University and the University of Melbourne, reported in the December International Journal of Eating Disorders, found that...

No Metabolic Risk for Antipsychotic-Naive Patients

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An Austrian study of the baseline prevalence of metabolic abnormalities and changes following treatment with five commonly-used antipsychotic drugs (haloperidol, amisulpride, olanzapine, quetiapine or...

Therapy Without Drugs May Ward Off Psychosis

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A double-blind, randomized, placebo-controlled study comparing outcomes from risperidone, cognitive therapy, and supportive therapy in a cohort of 115 at-risk young adults over a...

Four Leading Antipsychotics Aren’t Safe or Effective in Older Adults

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A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...

Pentagon Was Warned Off Antipsychotic for PTSD

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Despite 2004 clinical guidelines issued by the Veterans' Administration that "there is insufficient evidence to recommend atypical antipsychotics for the treatment of PTSD,"  ...

Antipsychotics Change the Architecture of the Colon

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Researchers in Singapore find that antipsychotic medications are associated with changes to colonic architecture, which could result in difficult colonoscopy and increased colonoscopy-related risks....

Discussing The Meaning of Antipsychotics

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Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...

Family Economic Context Linked to Adolescents’ Antipsychotic Use

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In a study of the Swedish Medical Birth Registry published in the British Medical Journal, researchers identified all 324,510 single children born between 1988...

2nd-Generation Antipsychotics Cause Extrapyramidal Side Effects as Much as 1st-Generation

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According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...

Off-Label Antipsychotic Use Among Children Soaring

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Researchers from Philadelphia and Baltimore find, in a study of Medicaid records for 50 states and the District of Columbia, that antipsychotic prescribing to...