Sunday, December 8, 2019

High Cost to Medicaid Programs For Off-Label Use of Antipsychotics

A study of 42 state Medicaid programs found that 58% of prescriptions for antipsychotics  were not for schizophrenia or bipolar disorder. Off-label prescribing was most prevalent...

45% of Children and Adolescent Inpatients Prescribed Antipsychotics

In a rare long-term study of antipsychotics used in children and adolescent inpatients, the Institute of Living in Hartford, CT followed 3,851 consecutive admissions...

WHO Says Newer Antipsychotics Most Costly, Least Effective Strategy

In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...

Rise of Antipsychotics in Children

Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...

Risk of Death in the Elderly Trebled With Antipsychotics

In a nine-year study of all 2,224 residents of Leppävirta, Finland who were 65 years old or older, researchers found that the 332 residents...

Cumulative Risk of Impairment and Death From Anticholinergic Medication

The New York Times reports that a two-year longitudinal study of over 13,000 men and women over 65 found that anticholinergic medications, which include many...

Antipsychotics for Dementia: Not Justified and Risky

In a study of antipsychotics used to treat 75,445 patients in nursing homes in the United States, researchers from Harvard Medical School, Columbia and...

Better Recovery and Less Relapse Without Meds: A 20-Year Study

Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...

Some Avoid Antipsychotics Because They Value Psychosis

Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...

Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse

In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

Antipsychotic Use Does Not Correlate With Conversion to Psychosis

Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

Assessing Increased Mortality Risks of Antipsychotics and Mood Stabilizers in Dementia

An article in January's American Journal of Psychiatry weighs the relative risk of mortality associated with various antipsychotics and mood stabilizers used in the treatment of...

Medications May Add to Mortality Rate in Schizophrenia

Dutch researchers write in the Journal of Clinical Psychopharmacology that, in a prospective study of 7415 persons with diagnoses of schizophrenia, use of a first-generation...

Discontinuing Psychotropics Reduces Falls in Elderly

Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

Antipsychotics Increase Retrovirus Activity in Humans

Endogenous retroviruses, remnants of ancient infections that have become part of the human genome, have been associated with the development of schizophrenia. But researchers...

Alarm About Antipsychotics as Sleep Aids

Canadian sleep researchers, writing in The Lancet, warn that weight gain, lipid and glucose dysregulation, restless leg syndrome, sleep-walking and eating while asleep, and...

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