Antipsychotics for Poor Kids Soar, Mostly for Behavior Problems
Cross-sectional analysis by the University of Maryland and Johns Hopkins University of 456,315 youths enrolled in Medicaid between 1997 and 2006 finds that the...
Antipsychotics for Depression: Added Risk for Little Benefit
A review of research on antipsychotic medications as an adjunctive treatment for depression published this week in PLoS Medicine finds that the widespread practice...
Antipsychotics do not Result in Neurocognitive Improvement
Researchers in London and Spain, in a prospective, randomized, study of long-term (3 year) effects of first- and second-generation antipsychotics on neurocognition in 79...
Antipsychotics Associated with White-Matter Reduction
Researchers in China find an acute reduction in white matter in the frontal lobe following six weeks of antipsychotic treatment for "first-episode schizophrenia". Results...
Antipsychotics are Common for the Mechanically Ventilated
Annals of Pharmacotherapy reports in a study of patients undergoing mechanical ventilation that 39% were given antipsychotic medication to prevent or treat delirium despite...
Increasing Use of Antipsychotics for Disruptive Behavior in Children
Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...
Majority of Anorexia Patients are Prescribed Psychotropics Despite Lack of Data
Research from the medical schools of Harvard University and the University of Melbourne, reported in the December International Journal of Eating Disorders, found that...
No Metabolic Risk for Antipsychotic-Naive Patients
An Austrian study of the baseline prevalence of metabolic abnormalities and changes following treatment with five commonly-used antipsychotic drugs (haloperidol, amisulpride, olanzapine, quetiapine or...
Therapy Without Drugs May Ward Off Psychosis
A double-blind, randomized, placebo-controlled study comparing outcomes from risperidone, cognitive therapy, and supportive therapy in a cohort of 115 at-risk young adults over a...
Four Leading Antipsychotics Aren’t Safe or Effective in Older Adults
A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...
Pentagon Was Warned Off Antipsychotic for PTSD
Despite 2004 clinical guidelines issued by the Veterans' Administration that "there is insufficient evidence to recommend atypical antipsychotics for the treatment of PTSD," ...
Antipsychotics Change the Architecture of the Colon
Researchers in Singapore find that antipsychotic medications are associated with changes to colonic architecture, which could result in difficult colonoscopy and increased colonoscopy-related risks....
Discussing The Meaning of Antipsychotics
Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...
Family Economic Context Linked to Adolescents’ Antipsychotic Use
In a study of the Swedish Medical Birth Registry published in the British Medical Journal, researchers identified all 324,510 single children born between 1988...
2nd-Generation Antipsychotics Cause Extrapyramidal Side Effects as Much as 1st-Generation
According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...
Off-Label Antipsychotic Use Among Children Soaring
Researchers from Philadelphia and Baltimore find, in a study of Medicaid records for 50 states and the District of Columbia, that antipsychotic prescribing to...
More Evidence That Antipsychotics Shrink the Brain
European researchers who reviewed 43 imaging studies of first-episode psychosis found evidence that antipsychotics cause a decrease in gray matter volumes in the brain....
Antipsychotics Rise in Youth, But Hospitalization Rates Stay the Same
Researchers from Tufts and Harvard find in a review of 233 medical charts of psychiatrically hospitalized youth at three points in time (1991, 1998...
BJP Announces “The End of the Psychopharmacological Revolution”
The editor of the British Journal of Psychiatry, in a comment on Morrison et al.'s "Antipsychotics: is it Time to Introduce Patient Choice," announces...
Antipsychotics for Childhood “Behavioral Problems” Skyrocket
Researchers from Columbia University and other New York institutions found a dramatically increasing use of antipsychotics to treat ADHD and other behavioral problems in...
British Journal of Psychiatry Editorial Urges Rethinking the Use of Antipsychotics
The August issue of the British Journal of Psychiatry offers an editorial stating that, as "mental health services appear to have overestimated the strength...
Antipsychotics Not Helpful for Anorexia
A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...
Nurses Confront the Myths of Psychiatric Drugs
The July issue of Nursing Ethics takes on the myths of psychiatric drugs, saying that "psychiatric drugs are used only to control ‘patient’ behaviour...
Antipsychotics During Pregnancy Raise Diabetes Risk
Swedish researchers find, in a study of all women giving birth in Sweden from July 1, 2005 through December 31, 2009 that those taking...
Little Evidence on Effectiveness or Risks of Antipsychotics in Young People
Evidence-Based Mental Health reviews studies (from 1987 to 2011) of antipsychotics in people under 24 years old, finding weak evidence on comparative effectiveness of antipsychotics or...
