Risk of Death in the Elderly Trebled With Antipsychotics
In a nine-year study of all 2,224 residents of Leppävirta, Finland who were 65 years old or older, researchers found that the 332 residents...
Elderly With Dementia can be Withdrawn From Antipsychotics
The Cochrane Library reports that "many older people with Alzheimer's dementia and NPS (neuropsychiatric symptoms) can be withdrawn from chronic antipsychotic medication without detrimental effects...
Antipsychotics for Poor Kids Soar, Mostly for Behavior Problems
Cross-sectional analysis by the University of Maryland and Johns Hopkins University of 456,315 youths enrolled in Medicaid between 1997 and 2006 finds that the...
Majority of Anorexia Patients are Prescribed Psychotropics Despite Lack of Data
Research from the medical schools of Harvard University and the University of Melbourne, reported in the December International Journal of Eating Disorders, found that...
Rise of Antipsychotics in Children
Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...
Less-impaired Youth Using Antipsychotics with Other Medications More Often
Use of second-generation antipsychotics (SGA) alongside other medications is growing rapidly among youth who are less impaired, according to a study published online in...
Alberta Long-term Care Homes Reduce Antipsychotic Use by 50%
The provincial government health service of Alberta, Canada recently concluded a successful pilot project that reduced the use of antipsychotic medications for patients with...
Antipsychotics Not Helpful for Anorexia
A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...
Pharmacological Treatment of Schizophrenia: a Fifty-Year Review
Researchers in the U.S. and India reviewed the pharmacological treatment of schizophrenia since its introduction 50 years ago, trying to understand why it "remains...
No Advantage for Second-Generation Antipsychotics
In a study of 720 consecutive hospital admissions in a specific catchment area from 1991 to 2005, researchers found that there was no difference...
High Cost to Medicaid Programs For Off-Label Use of Antipsychotics
A study of 42 state Medicaid programs found that 58% of prescriptions for antipsychotics were not for schizophrenia or bipolar disorder. Off-label prescribing was most prevalent...
Multiple Medications Associated With Poorer Outcomes
Research from Germany finds that people with schizophrenia or schizoaffective diagnoses given multiple medications - an antipsychotic plus a benzodiazepine or more than one...
WHO Says Newer Antipsychotics Most Costly, Least Effective Strategy
In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...
Family Economic Context Linked to Adolescents’ Antipsychotic Use
In a study of the Swedish Medical Birth Registry published in the British Medical Journal, researchers identified all 324,510 single children born between 1988...
Increasing Use of Antipsychotics for Disruptive Behavior in Children
Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...
Baseline Lipid Monitoring with Antipsychotics “Disappointingly Low”
"Even in an academic setting with active discussions among psychiatrists regarding issues of metabolic risk ... baseline lipid monitoring is disappointingly low" according to...
Antipsychotics for Dementia: Not Justified and Risky
In a study of antipsychotics used to treat 75,445 patients in nursing homes in the United States, researchers from Harvard Medical School, Columbia and...
Therapy Without Drugs May Ward Off Psychosis
A double-blind, randomized, placebo-controlled study comparing outcomes from risperidone, cognitive therapy, and supportive therapy in a cohort of 115 at-risk young adults over a...
Prenatal Antipsychotic Exposure Causes Neuromotor Deficits
Researchers studying 309 6-month-olds at Emory University's Infant Development Laboratory found that infants prenatally exposed to antipsychotics showed significantly lower scores on a standardized...
Some Avoid Antipsychotics Because They Value Psychosis
Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...
Psychotropics During Pregnancy Raise Risk of Babies with Low Birth Weight, Hospitalizations
The use by mothers of any of four major classes of psychiatric medications during pregnancy significantly raises the risk that their babies will be born with low birth weights and will need to be hospitalized.
Scant Evidence for Combining Antipsychotics
Researchers in Barcelona, Spain retrospectively reviewed the use of antipsychotics in 117,811 patients, of whom 9,855 were given combinations of antipsychotics and 13,763 were...
Pharmacology Gets More Cooperation Than Psychosocial Advice
In a study of conformance to evidence-based treatment recommendations at mental health clinics among people diagnosed with schizophrenia, Canadian researchers found that conformance to...
Discussing The Meaning of Antipsychotics
Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...
Little Evidence on Effectiveness or Risks of Antipsychotics in Young People
Evidence-Based Mental Health reviews studies (from 1987 to 2011) of antipsychotics in people under 24 years old, finding weak evidence on comparative effectiveness of antipsychotics or...
