Alarming Report on Antidepressant Side Effects
Drawing on analysis of data from websites such as Paxilprogress.org, ehealthforum.com, depression forums.org, about.com, medhelp.org, drugLib.com, topic.com and survivingantidepressants.org, researchers from the University of...
Antipsychotics for Poor Kids Soar, Mostly for Behavior Problems
Cross-sectional analysis by the University of Maryland and Johns Hopkins University of 456,315 youths enrolled in Medicaid between 1997 and 2006 finds that the...
Antipsychotics for Depression: Added Risk for Little Benefit
A review of research on antipsychotic medications as an adjunctive treatment for depression published this week in PLoS Medicine finds that the widespread practice...
Antipsychotics do not Result in Neurocognitive Improvement
Researchers in London and Spain, in a prospective, randomized, study of long-term (3 year) effects of first- and second-generation antipsychotics on neurocognition in 79...
Internet Data Mining Reveals Unreported Side Effect
Scientists at Microsoft, Stanford and Columbia University, using automated software to mine data from 82 million internet searches for information related to, found a...
Antipsychotics Associated with White-Matter Reduction
Researchers in China find an acute reduction in white matter in the frontal lobe following six weeks of antipsychotic treatment for "first-episode schizophrenia". Results...
Benzos Alter Fish Behavior
Drugs that pass into the water supply can alter the behavior of fish, according to a paper published today in Science magazine. Experiments using...
Psychotropics Significantly Increase Falls in the Elderly
Psychotropic medications, including short-acting benzodiazepines, strongly increase the frequency of falls in the elderly, according to research from the Netherlands published in Maturitas: The...
Antipsychotics are Common for the Mechanically Ventilated
Annals of Pharmacotherapy reports in a study of patients undergoing mechanical ventilation that 39% were given antipsychotic medication to prevent or treat delirium despite...
Antidepressants Linked to Heart Arrhythmias
Researchers from the Mass General and Brigham & Women's Hospitals and the Mt. Sinai School of Medicine find, using data from electronic health records...
Increasing Use of Antipsychotics for Disruptive Behavior in Children
Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...
Majority of Anorexia Patients are Prescribed Psychotropics Despite Lack of Data
Research from the medical schools of Harvard University and the University of Melbourne, reported in the December International Journal of Eating Disorders, found that...
Benzodiazepines May Double the Risk of Pneumonia
An editorial in Thorax reviews the evidence for an association between mental illness, benzodiazepine use, and pneumonia. The authors find an equally augmented rate...
No Metabolic Risk for Antipsychotic-Naive Patients
An Austrian study of the baseline prevalence of metabolic abnormalities and changes following treatment with five commonly-used antipsychotic drugs (haloperidol, amisulpride, olanzapine, quetiapine or...
Therapy Without Drugs May Ward Off Psychosis
A double-blind, randomized, placebo-controlled study comparing outcomes from risperidone, cognitive therapy, and supportive therapy in a cohort of 115 at-risk young adults over a...
Four Leading Antipsychotics Aren’t Safe or Effective in Older Adults
A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...
Pentagon Was Warned Off Antipsychotic for PTSD
Despite 2004 clinical guidelines issued by the Veterans' Administration that "there is insufficient evidence to recommend atypical antipsychotics for the treatment of PTSD," ...
Antipsychotics Change the Architecture of the Colon
Researchers in Singapore find that antipsychotic medications are associated with changes to colonic architecture, which could result in difficult colonoscopy and increased colonoscopy-related risks....
Genetic Markers do not Predict Response to Antidepressants
Researchers from 11 nations in Europe and North America find, in the largest study to date of possible links between genetic markers and antidepressant...
SSRIs Increase Risk of Brain Hemorrhage
Canadian researchers, publishing in Neurology, find in a meta-analysis of controlled observational studies comparing SSRI therapy with a control group that SSRI exposure increased...
The Putative Neurobiology of SSRIs and Aggression
“It’s happening," said researchers at Northeastern University, "Kids are becoming irritated, aggressive, impulsive, agitated, hostile. So you ask the question: Why?” They found (through study...
Discussing The Meaning of Antipsychotics
Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...
Benzos Raise Dementia Risk 50%
A 15-year prospective study, in the British Medical Journal this week, of 1063 subjects by researchers from the University of Bordeaux and Harvard University...
Antidepressants Linked to Risk of Adult-Onset Diabetes
A meta-analysis of studies of 168,435 adults who were free of diabetes at baseline found that those who used antidepressant medication were 68% more...
Family Economic Context Linked to Adolescents’ Antipsychotic Use
In a study of the Swedish Medical Birth Registry published in the British Medical Journal, researchers identified all 324,510 single children born between 1988...
