Science of Psychiatric Drugs

The addition of fluoxetine to CBT did not further reduce depressive symptoms in young people with moderate-to-severe depression.

Common psychiatric medications double the risk of heart attack and triple the risk of stroke, according to research presented at the Canadian Cardiovascular Congress...

Researchers examine psychiatrist-client interactions and find that clients are often left with few opportunities to make explicit requests to change their medication regimen.

-SSRI antidepressant medications contribute to a significant worsening of emotional "rapid cycling" in patients diagnosed with bipolar disorder.

Study finds antidepressant use is linked to increase in hip fractures in community-dwelling older adults with and without Alzheimer’s disease.

Researchers at the University of Milan and King's College, London thoroughly reviewed the literature available on Medline and Cochrane regarding the use of benzodiazepines...

Author William Styron is often remembered for speaking about depression as an illness. But a review of his life reveals that psychiatric drugs may have triggered and even worsened his depressive episodes.

A team of psychiatrists reviewed 654 cases in West Ireland to find that nearly 1% of all patients taking the antipsychotic clozapine had experienced clozapine-induced stuttering.

Experts advocate limiting antidepressant use to only the most severe cases of depression, emphasizing the need for social and psychological interventions.

Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...

A group of researchers recently found serious bias in the reporting of harm due to adverse events in antidepressant medication clinical trials. They report...

An article by written by faculty of the Harvard History of Science Department and the Program in Placebo Studies explores how "drug marketing portrays...

An equal percentage of young people will start misusing ADHD-related and other stimulant drugs for the first time at age 13 as will start at age 20.

Study reviews psychological interventions for antidepressant discontinuation.

Patient advocates join with researchers and service users to present first-hand experiences of antidepressant withdrawal.

After 18 years, the full story of the scientific corruption in a study of paroxetine for bipolar disorder, and the psychiatrist who blew the whistle.

Drexel University researchers found that methylphenidate (Ritalin) administered to juvenile rats produced significant depressive effects on pyramidal neurons. The authors conclude that "the juvenile...

Antidepressants have been reported to cause a state called “akathisia,” where people feel extremely agitated and restless and may become preoccupied with thoughts of...

A new study has found a strong association between antipsychotic drugs and higher rates of severe cases of COVID-19.

Research published in the Journal of Psychiatric Practice finds that a "shared discussion of beliefs about medication between patient and care provider allows wider...

Researchers argue for a shift away from a focus on antipsychotic adherence toward understanding service users’ diverse patterns of use.

Researchers from Samaritan Mental Health in Corvallis, Oregon successfully treated 12 patients for anxiety by discontinuing their antidepressant medications. Some received alternative medications for...

Researchers Identify risk factors for long-term benzodiazepine use to prevent harmful effects.

Drugs to treat serious or life-threatening conditions can receive accelerated FDA approval, but may expose patients to increased safety risks and reduced efficacy.

In a study of 69,448 pregnant women with depression, researchers from the Harvard school of public health found that use of SSRI (selective serotonin...