Exploring Psychiatry’s “Black Hole”: The International Institute on Psychiatric Drug Withdrawal

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When Carina Håkansson sent out an invitation for a symposium on "Pharmaceuticals: Risks and Alternatives," some of the world's top scientists, along with experts-by-experience, came from 13 countries to explore better ways to respond to people in crisis.

Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorder

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Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.

Antipsychotics Even Riskier For The Elderly Than Previously Thought

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Antipsychotic medications that are commonly being used to help control behaviors in elderly people with dementia seem to be causing premature deaths at high rates.

Research Finds Ketamine Does Not Reduce Delirium or Pain After Surgery

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Contrary to widely-held belief, a new rigorous trial finds that ketamine is ineffective for delirium and pain associated with surgery, and the drug carries harmful side effects.

The Impact of Regression to the Mean in Psychiatric Drug Studies

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Could the statistical phenomenon of regression to the mean be responsible for the dramatic effects of placebo—as well as the supposed effectiveness of some psychiatric drugs?

Study Explores Cognitive Effects of Antipsychotics

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Reduced usage of antipsychotics in first-episode psychosis was associated with improved executive functioning.

Antidepressants During Pregnancy Increase Risk of Psychiatric Diagnosis in Children

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New research, based on data from almost a million children in Denmark, suggests that children of mothers who use antidepressants during pregnancy are more likely to be diagnosed with autism and psychiatric disorders.

Antidepressants Do Not Prevent Suicides, May Increase Risk

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When the CDC released data revealing an increasing suicide rate in the US, some experts, speaking to major media outlets, speculated that the increase...

Lexapro for Children: Drug With No Meaningful Benefit and Increased Suicidality Gets FDA Approval

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Response and remission rates were the same in the drug versus placebo groups, and Lexapro increased suicidality sixfold.

Psychiatric Drugs Do Not Improve Disease or Reduce Mortality

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Nassir Ghaemi: “Most psychiatric medications are purely symptomatic, with no known or proven effect on the underlying disease. They are like 50 variations of aspirin, used for fever or headache, rather than drugs that treat the causes of fever or headache.”

World Benzodiazepine Awareness Day 2020

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This week on MIA Radio, we present the second part of our podcast to join in the events for World Benzodiazepine Awareness Day 2020...

Half of First-Episode Patients Respond to Antipsychotics

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No placebo controlled trials provide evidence of antipsychotics in first-episode psychosis.

Government Calls US Benzodiazepine Prescription Levels “Worrisome”

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Despite the well-known risks of the drugs, especially for the elderly, prescription use of addictive benzodiazepine sedatives in the United States increases steadily with age, according to a large-scale study published in JAMA Psychiatry. Overall, as of 2008, 5.2% of American adults were taking the drugs. The study also showed that women were twice as likely to be taking benzodiazepines as men. National Institute of Mental Health director Thomas Insel called the findings "worrisome."

Suicide in the Age of Prozac

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During the past twenty years, the American Foundation for Suicide Prevention and American psychiatry have adopted a "medicalized" approach to preventing suicide, claiming that antidepressants are protective against suicide. Yet, the suicide rate in the United States has increased 30% since 2000, a time of rising usage of antidepressants. A review of studies of the effects of mental health treatment and antidepressants on suicide reveals why this medicalized approach has not only failed, but pushed suicide rates higher.

How Do Antidepressants Really ‘Work’?

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A recent review, published in Neuroscience & Biobehavioral Reviews, challenges the dominant assumptions about the neurochemical and therapeutic effects of Selective Serotonin Reuptake Inhibitors...
Vector-style illustration depicting men and women chained to a giant pill bottle

Researchers Identify Factors to Predict Risk of Antidepressant Withdrawal

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Paroxetine, SNRIs, and MAOIs were associated with the highest risk of withdrawal, as was long duration of use and whether the person experienced withdrawal in the past.

New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”

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A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”

Antidepressant Use Associated With Menstruation Disorders

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In a study of 793 women taking antidepressants and 639 not taking them, researchers in Turkey found that menstruation disorders were significantly associated with...

Acute Respiratory Failure More Likely in COPD Patients Prescribed Antipsychotics

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Researchers recommend that healthcare professionals be vigilant regarding the signs of respiratory failure among patients with COPD who are receiving antipsychotics, especially during the initial treatment phase.

Animals Exposed to Antidepressants in Utero Are Worse at Taking Care of Their Own...

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A new study in rats found that those exposed to antidepressants in utero had an impaired ability to nurture their own children in later life.
A box of Zyprexa pills.

Lack of Clear Guidelines Prevent Clinicians from Reducing Antipsychotics

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A recently published study from noted critical psychiatry expert Joanna Moncrieff explored the barriers that prevent clinicians from helping service users in discontinuing or...

NICE Guideline Update Acknowledges Severe Antidepressant Withdrawal

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A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.

Guidelines Recommending Antidepressants “in Contradiction with the Current Evidence”

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Researchers critique the German S3 guidelines for depression promoting antidepressants.

New Data Show Lack of Efficacy for Antidepressants

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An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.

Benzodiazepine Prescriptions in Older Adults Used in Rural and Low Income Areas

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Benzodiazepine prescription practices may be in response to an epidemic of distress, rather than being used to treat specific mental health diagnoses.