Better Recovery and Less Relapse Without Meds: A 20-Year Study

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Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...

Strategies for Tapering and Discontinuing Antidepressants

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A new review of strategies to support both patients and practitioners through the process of discontinuing antidepressants.

An FDA Whistleblower’s Documents: Commerce, Corruption, and Death

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In 2008, a reviewer of psychiatric drugs at the FDA, Ron Kavanagh, complained to Congress that the FDA was approving a new antipsychotic that was ineffective and yet had adverse effects that increased the risk of death. Twelve years later, a review of the whistleblower documents reveal an FDA approval process that can lead to the marketing of drugs sure to harm public health.
Pattern of blue and yellow pills or tablets on a pink background. concept of medicine, pharmacy and coronavirus. copy space

SSRI Withdrawal has Social, Cognitive, and Emotional Consequences

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New research finds that the non-physical aspects of withdrawal from SSRIs are often overlooked.

Getting Pharma Out of Medical Education: An Interview with Dr. Adriane Fugh-Berman

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MIA's Gavin Crowell-Williamson interviews PharmedOut founder Dr. Adriane Fugh-Berman about Big Pharma's influence on medical education.

Common Side Effects Leading to Antidepressant Discontinuation

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New research finds the negative drug effects most commonly associated with initiating antidepressant discontinuation are anxiety, suicidal thoughts, vomiting, and rashes.

Antipsychotics During Pregnancy Raise Diabetes Risk

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Swedish researchers find, in a study of all women giving birth in Sweden from July 1, 2005 through December 31, 2009 that those taking...

Anticonvulsant Implicated in Birth Defects in up to 4,100 Children, French Study Finds

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Between 2,150 and 4,100 children suffered from severe malformations connected to valproate prescription.

Therapy Better than Antidepressants for Staying Employed

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Examining the link between depression and loss of employment, a study by American researchers in the British Journal of Psychiatry found that cognitive therapy...

JAMA Review Questions Use of Ritalin for ‘ADHD’

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In December, MIA  reported on a systematic Cochrane review on the research for the safety and effectiveness of Ritalin (methylphenidate) that found substantial bias...

Ketamine for Harmful Drinking: A Look at the Data

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New research contends that ketamine can reduce problematic alcohol use but does the data support the claims?

SSRI Use During Pregnancy Alters the Child’s Brain Development

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Reduced brain volumes due to SSRI exposure in pregnancy was not explained by maternal depression alone.

Antidepressant Use May Increase Risk of Diabetes

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New study confirms previous evidence that antidepressant use is linked to developing type 2 diabetes.

Brain Response to Antidepressant Mirrors Placebo Effect

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People diagnosed with severe depression show the same changes in brain scans when they respond to a placebo as they do when they take an actual antidepressant, according to a new study. Researchers also found that those whose symptoms were decreased by a placebo were more likely to report relief from antidepressant drugs.

Study Identifies Link Between Antidepressants and Newborn Hypertension

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A new study, published in the American Journal of Physiology, investigates how the use of antidepressants during pregnancy can lead to a life-threatening lung...
3D render of placebo pills isolated over wood background

Placebo Effect—Not Antidepressants—Responsible for Depression Improvement

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In adolescent depression treatment, those who received a placebo but thought they received Prozac improved more than those who received the drug and knew it.

Researcher Challenges Clinical Effectiveness of Antidepressants

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A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.

Despite Safety Risks, Prescribers Receive Little Guidance of Monitoring Antipsychotic Clozapine

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A new review finds a lack of available guidance on how to effectively monitor adverse effects of antipsychotic drug clozapine.

Study Highlights Difficulty of Antipsychotic Withdrawal

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New research finds insomnia, anxiety, and depression are common symptoms of antipsychotic withdrawal, highlighting difficulties of discontinuation.

SSRIs May Cause Bone Loss

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An Israeli study of 10,621 women found that those taking an SSRI more than 80% of the time were 1.4 times more likely to...

Four Leading Antipsychotics Aren’t Safe or Effective in Older Adults

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A 5-year study funded by the National Institute of Mental Health and conducted by U.C. San Diego School of Medicine, Stanford University and the...

Poor Evidence and Substantial Bias in Ritalin Studies

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The authors of a large scale well-conducted systematic review of methylphenidate, also known as Ritalin, conclude that there is a lack of quality evidence for the drug’s effectiveness. Their research also revealed that Ritalin can cause sleep problems and decreased appetite in children.

Researchers Search for Subgroups Where Antidepressants Are More Effective

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The researchers theorized that this increased effectiveness was due not to “antidepressant” properties, but rather to the drug’s side effects, which include insomnia, drowsiness, and nausea.
Picture of distressed man facing pills

What Helps Long-Term Users of Benzodiazepines and Z-Drugs Discontinue?

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Current long-term users of benzodiazepines and Z-drugs identify barriers and facilitators for discontinuation.
antipsychotic drugs

Antipsychotic Augmentation Increases Risk of Death

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A new study finds that adding an antipsychotic to existing antidepressant treatment is associated with a 45% increased risk of early death.