Antidepressants Increase Suicide Risk in Children and Adolescents
In a meta-analysis of studies of 6039 individuals, researchers in the UK determined that, consistent with previous meta-analysses, antidepressants increased "suicide-related outcomes."
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‘Salami Slicing’ Found in Analyses of Antipsychotic Trials
Evidence of duplicate publishing in articles analyzing data from clinical trials testing second-generation antipsychotics for depression
Long Term Antidepressant Use Associated With Increased Morbidity and Mortality
A study finds that commonly prescribed antidepressants are associated with the development of diabetes, hypertension, and other diseases.
New Form of Mice Experiment Reveals Antidepressant’s Dangers Earlier
Scientists from the University of Utah say they have discovered a new way of doing mice experiments that more sensitively and quickly reveals negative...
Antidepressant Exposure In Utero May Negatively Impact Motor Skills in 2-Year-Old Children
A new study in Frontiers of Pharmacology finds that antidepressant use during pregnancy is linked to reduced motor skills in children at 2 years...
Antipsychotic Use in Nursing Homes Causing Many Adverse Effects in Elderly
A literature review found that the extensive off-label use of antipsychotic medications in nursing homes is causing many adverse effects and providing limited benefits.
Antidepressant Use Leads to Worse Long Term Outcomes, Study Finds
Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.
Hypertension in Pregnancy 50% More Likely With SSRIs
Researchers in Montreal found in a sample of 1,216 pregnant women that those who used antidepressants were at least 50% more likely to experience...
Antipsychotics Not Helpful for Anorexia
A review of all research on the use of antipsychotics for the treatment of anorexia nervosa found no demonstrable efficacy in terms of body...
Why the Delay Between Psychotropics’ Immediate and “Therapeutic” Effects?
Writing in Neuron that antipsychotics' "functional consequences and the subcellular sites of their accumulation in nervous tissue have remained elusive," researchers from Germany and...
Antidepressant Withdrawal Symptoms Linked to Life-Altering Consequences, New Study Shows
A new study reveals that withdrawal symptoms from antidepressants can last years, disrupting lives and relationships.
Increased Risk of Preterm Birth in Women Taking Antidepressants
A detailed meta-analysis of the published research on women taking antidepressants during pregnancy finds that the rate of preterm birth is nearly doubled in the third...
Increasing Use of Antipsychotics for Disruptive Behavior in Children
Canadian researchers systematically reviewed all randomized controlled trials of second-generation antipsychotics (SGAs) and placebo in the treatment of disruptive behavior disorders in children, finding...
Antipsychotics Linked to Increased Breast Cancer Risk
Long-term exposure to prolactin-increasing antipsychotics increases the odds of developing breast cancer.
Researchers Challenge Evidence for Antidepressants in Youth
Researchers shed light on the precarious nature of evidence from efficacy trials of antidepressant medication to treat symptoms of major depressive disorder in children and adolescents.
Report Calls For Policy Changes In Response To Dependence and Withdrawal From Prescribed Drugs
Statistics from the UK reveal that prescriptions for painkillers and antidepressants continue to rise despite concerns over dependence and debilitating withdrawal effects. The British Medical Association (BMA) Board of Science has released a report that acknowledges changes to medical practice, research and policy necessary for addressing the dependence and withdrawal effects of benzodiazepines, opioids, and antidepressants.
Is Long-term Use of Benzodiazepines a Risk for Cancer?
A large study of the population in Taiwan reveals that long-term use of benzodiazepine drugs, commonly prescribed for anxiety, significantly increases the risk for brain, colorectal, and lung cancers. The research, published open-access in the journal Medicine, also identifies the types of benzodiazepines that carry the greatest cancer risk.
SSRI Does Not Improve Outcomes or Mood for Patients with Heart Failure
A study released this week in JAMA examined whether giving patients with chronic heart failure and depression the SSRI antidepressant escitalopram (Lexapro) for two...
Psychotropic Medications Serve as Powerful Tools for U.S. Military, Imperialism
Ethnographic research sheds light on extensive psychopharmaceutical use by soldiers in post 9/11 U.S. wars.
Animal Study: SSRI Neurotoxic in Pregnancy
Researchers: Fetal exposure to vilazodone hampers neurodevelopment and leads to "long-lasting neurodevelopmental impairments."
Hyperbolic Tapering off Antidepressants Limits Withdrawal
New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.
Antidepressants Linked to Risk of Adult-Onset Diabetes
A meta-analysis of studies of 168,435 adults who were free of diabetes at baseline found that those who used antidepressant medication were 68% more...
Benzodiazepines May Double the Risk of Pneumonia
An editorial in Thorax reviews the evidence for an association between mental illness, benzodiazepine use, and pneumonia. The authors find an equally augmented rate...
Antiseizure Drug Exposure in Pregnancy Linked to Large Risk of Autism, ADHD, and Intellectual...
Harms are “largely overlooked by psychiatry despite widespread usage,” according to the researchers.
Stuart Shipko – SSRI Withdrawal: Shooting the Odds
We interview Dr. Stuart Shipko, a psychiatrist and author who has a particular interest in the side effects and withdrawal effects of SSRI antidepressants and the need for informed consent when prescribing.