Sunday, February 5, 2023

Tag: alzheimer’s

FDA Approves Failed Alzheimer’s Drug

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The FDA approved Biogen's failed drug aducanumab, overriding the 10-0 recommendation of its own advisory committee. Three panel members resigned in protest.

Drug May Lead to Early Death for People With Alzheimer’s

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From The Washington Post: A recent study found that benzodiazepines are associated with a greater chance of early death for those with Alzheimer's. "Researchers analyzed data on...

The Drug Being Pushed on Nursing Home Residents

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From Next Avenue: The drug Nuedexta has only been approved for patients with multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS). However, the maker of...

Lifestyle Changes, Not a Magic Pill, Can Reverse Alzheimer’s

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From Aeon: A recent study at UCLA found that lifestyle changes including diet modifications, exercise, stress management, and increased sleep can significantly improve the memory and...

New Medications Fail to Show Efficacy for Alzheimer’s Disease

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Three phase III clinical trials assessing the efficacy of Lundbeck’s investigational drug idalopirdine for Alzheimer’s disease have failed

BPS Releases Review of Alternatives to Antipsychotics

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BPS releases report encouraging behavioral interventions for people with dementia, rather than antipsychotics

“Their Brains had the Telltale Signs of Alzheimer’s. So why did...

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Sharon Begley for the STAT examines new research which raises “doubts about conventional approaches to diagnosing and finding treatments for Alzheimer’s.” Article →

My Father-in-law on Risperdal — A Case Study Gets Personal

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Risperdal is increasingly used in nursing homes for “agitation,” especially on those suffering from some form of dementia, even when no hallucinations or delusions are observed. Risperdal has quite a long list of side effects including heart problems, metabolic difficulties, diabetes, involuntary movements, agitation, flat affect and sedation. Risperdal has earned a “black box" warning that its use in those with Alzheimer's increases the risk of earlier death. Yet its use in Alzheimer's patients in nursing homes is extremely common.