Wednesday, October 17, 2018

SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms

New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

Researcher Challenges Clinical Effectiveness of Antidepressants

A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.

Hallucinations Reported as Side Effect of ADHD Medication

Hallucinations and other psychotic symptoms have been reported after methylphenidate (Ritalin) treatment for ADHD.

Large Increase in Poison Control Calls for Children Taking ADHD Drugs

New data shows that calls to US poison control centers have increased significantly for children taking stimulant ADHD drugs.

SSRI Exposure in Pregnancy Alters Fetal Neurodevelopment

Alterations in gray matter and white matter development found in infants of mothers taking SSRI antidepressants during pregnancy.
prescriptions and suicide

Suicides Are Increasing – And So Are Antidepressant Prescriptions

Disturbingly, our study and others reveal that the black box warning is now ignored in many countries, since antidepressant prescriptions for children are on the rise again. Despite increasing certainty that antidepressants are ineffective and likely cause suicidal behavior in young people, psychiatry continues to claim that they reduce suicide risk.

Call to Monitor Adverse Effects of Antipsychotics in Youth

Researchers point to the risks of using antipsychotics with youth and caution against the practice.
psychiatric drugs and violence

Prescripticide: A Proposal for Action and a Request for Your Help

The primary factor protecting psychiatry’s unwarranted power and authority is that it is perceived as shielding society from folks who are believed to be dangerous. It would seem, then, that one logical step toward reducing society’s trust in biological psychiatry would be to reveal the evidence of a significant correlation between the use of prescribed psychoactive drugs and the commission of violent acts against oneself or others.

Study Shows Success With Reduced Antipsychotic Use

People who reduced antipsychotic use by tapering were doing just as well after five years as those who continued using the drugs.

Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorder

Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.

Study Reduces Over-prescription of Antipsychotics in Older Adults

New intervention shows promise in reducing over-prescription of off-label antipsychotics in older adults.

Unsafe Use of Sleep Drug Zolpidem is Common

Three out of four users of the sedative, zolpidem (brand name Ambien), do not follow FDA recommendations to reduce risk.

New Research Suggests Brain Abnormalities in ‘Schizophrenia’ May Result From Antipsychotics

Study finds that reduced cortical thickness and brain surface area associated with 'schizophrenia' may result from antipsychotic drug use.

FDA Defends Decision to Approve Digital Aripiprazole

Members of the U.S. Food and Drug Administration’s Psychiatry Products division go on the defensive in a new article, responding to concerns about the agency’s approval of digital aripiprazole.

Addressing Depression and Heart Disease with Exercise and Physical Activity

A new study examines the effects of midlife exercise on depression and cardiovascular health later in life.

Research Finds Parents’ Trauma May Impact Children’s Health

Study uncovers some of the intergenerational consequences of adverse childhood experiences (ACEs).

Citizens Petition Calls for Sexual Side Effect Warnings

Researchers take action after study exposes enduring sexual dysfunction as a potential side effect of serotonin reuptake inhibiting antidepressants, 5α-reductase inhibitors, and isotretinoin.

Despite the Evidence, Overprescription of Stimulants Continues

A new study finds that stimulant prescribing rates to children continue to rise despite the well-established evidence documenting overdiagnosis of ADHD and overprescription of stimulants.
risk versus reward

Randomized Controlled Trials of Psychiatric Drugs Tell of Harm Done

The most important data in an RCT is not whether the drug provides a statistically significant benefit over placebo. The most important data is the “number needed to treat” calculation (NNT). For the person considering taking an antidepressant or an antipsychotic, the NNT data provides the “math” needed to weigh the potential benefit of taking the drug against the potential harm of doing so.
man contemplates suicide

Rising Rates of Suicide: When Do We Acknowledge That Something Isn’t Working?!

Scapegoating a purported unseen "illness" may provide temporary comfort from acknowledging the horrors and injustice of the world, but it is a delusion — and one with fatal consequences for many. When 45,000 people a year would rather die than live in this world any longer, it might behoove us all to consider what is happening in the world to cause this.

Review of Pediatric Antidepressant Studies Finds Evidence of Benefit Lacking

Review of pediatric antidepressant studies finds the vast majority are negative on primary outcomes and an increased risk for suicidality.

New Clinical Guidelines on Deprescribing Benzodiazepines

New guidelines recommend deprescribing benzodiazepine receptor agonists for adults.

Unnecessary and Accidental Use of ADHD Drugs Increases

From CNN: According to a new study, exposure to unprescribed ADHD drugs has increased by more than 60% among U.S. children since 2000. "The study, published Monday...

Review Finds Lack of Evidence for Antidepressants in Treatment of Insomnia

Results from a Cochrane meta-analysis find that the common practice of prescribing antidepressants to treat insomnia is not supported by current evidence.

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