Tuesday, February 7, 2023

Tag: biomarkers

A Neuroscientist Evaluates the Standard Biological Model of Depression

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Current evidence does not support a biological hypothesis of depression. It is far better predicted by levels of childhood trauma, life stress, and lack of social supports.

It is Time to Abandon the Candidate-Gene Approach to Depression

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The candidate-gene approach to depression goes unsupported and is likely based on bad science, new research finds.

Philosophers Challenge Psychiatry and its Search for Mechanisms of Disorder

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Attempting to locate the mechanisms of psychiatric disorder is a step in the wrong direction and fails to challenge potentially unjust social practices.

Large Rigorous Study Debunks Popular Gene-Environment Theory of Depression

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A large and rigorous meta-analysis fails to find support for the gene-environment interaction theory of depression.

Bipolar Diagnosis Linked to Childhood Adversity

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With the ties between traumatic childhood experiences and mental health issues, should we continue to focus on biological approaches?

The Failed Quest for Biomarkers in Psychiatry

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A recent commentary by Ganesan Venkatasubramanian and Matcheri Keshavan notes that efforts to identify biomarkers in people diagnosed with psychiatric disorders have been overwhelmingly...

Dr. Nardo on the Curse of Insel’s Legacy

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In his reaction to Dr. Makari’s Opinion piece in the ‘Times, entitled Psychiatry’s Mind-Brain Problem, Dr. Nardo articulates why the legacy of NIMH director Thomas Insel is so dangerous. “He may have kept the researchers from spinning off and following some idiosyncratic path, but he did it by forcing them to follow his own idiosyncratic path.”

ADHD: A Destructive and Disempowering Label; Not an Illness

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In recent years, we've seen an increasing number of articles and papers from psychiatrists in which they seem to be accepting at least some of the antipsychiatry criticisms, and appear interested in reforms. It is tempting to see this development as an indication of progress, but as in many aspects of life, things aren't always what they seem.