Tag: antidepressants

Antidepressant Trials “Hijacked for Marketing Purposes,” Researchers Say

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About half of the large antidepressant trials are biased enough to be considered “seeding trials,” according to the researchers.

Deprescribing Psychiatric Drugs to Reduce Harms and Empower Patients: Interview with...

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Ayurdhi Dhar interviews psychiatrist Swapnil Gupta on psychiatric drug discontinuation, drug cocktail risks, patient choice, and the need for trust and transparency.

Antidepressant Use Linked to Sexual Dysfunction, Why Aren’t Prescribers Discussing It?

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Research sheds light on the impact of antidepressants on sexual dysfunction, emphasizing the need for patient-physician communication.

Antidepressant Use Tightly Correlates with Increased Suicide Rates

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While the study can’t confirm causality, it does contradict the notion that antidepressants reduce suicide at the population level.

Two Out of Three Find Antidepressant Effects Not Worth Burdens

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New study reveals: 2 in 3 people need more than the current antidepressant benefits to consider them worthwhile.

SSRI Withdrawal has Social, Cognitive, and Emotional Consequences

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New research finds that the non-physical aspects of withdrawal from SSRIs are often overlooked.

Winding Back the Clock: What If the STAR*D Investigators Had Told...

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The STAR*D Study has been cited as real-world evidence of the efficacy of antidepressants. In truth, it told of a failed paradigm of care.

Antidepressant Exposure In Utero May Negatively Impact Motor Skills in 2-Year-Old...

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A new study in Frontiers of Pharmacology finds that antidepressant use during pregnancy is linked to reduced motor skills in children at 2 years...

Placebo Effect—Not Antidepressants—Responsible for Depression Improvement

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In adolescent depression treatment, those who received a placebo but thought they received Prozac improved more than those who received the drug and knew it.

Robert Whitaker Answers Reader Questions on Pharma Marketing and Psychiatric Drugs

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In Part 2 of our reader Q&A podcast, MIA founder Robert Whitaker answers questions on pharmaceutical marketing and issues with psychiatric treatments including psychiatric drugs and electroconvulsive therapy.

Stop Using Antidepressants Except for “the Most Severe Depression,” Experts Say

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Experts advocate limiting antidepressant use to only the most severe cases of depression, emphasizing the need for social and psychological interventions.

Animal Study Shows Impact of Prozac in Pregnancy on the Child

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Researchers found that rats born to mothers given the antidepressant Prozac during pregnancy or breastfeeding exhibited varied behavioral and developmental effects, with implications for the understanding of antidepressant impacts during human pregnancies.

Psychiatric Journals’ Pro-Pharma Publication Bias Hides Suicide Risk of Antidepressants

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Selective publication bias in top psychiatry journals was not explained by the quality of the studies, but by financial ties to pharma.

Antidepressants Increase Suicide Attempts in Youth; No Preventative Effect

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Researchers find that SSRIs increase suicide attempts up to age 24, and have no preventative effect at any age, even for those at high risk of suicide.

No Benefit for Adding Antidepressants to CBT in Severe Depression

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For those with severe depression, inpatient CBT was effective but the adding antidepressants did not improve treatment outcomes.

New Data Reveal the Full Extent of STAR*D Failure

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The initial study, which has been used to promote antidepressants, employed outcome switching to hide poor results.

Patients Express Anger at Doctors’ Ignorance About Antidepressant Withdrawal Effects

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Antidepressant users share their frustrations towards a healthcare system that overprescribes but is ill-equipped to support with discontinuation and withdrawal symptoms.

Antidepressants, Antipsychotics, and Benzos All Increase Suicide Attempts in New Study

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In a study of people with borderline personality disorder, only ADHD stimulants were associated with a decrease in suicide.

Pharma CEO, Others Attempt Contradictory Critiques of Serotonin-Debunking Study

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Moncrieff et al. respond to the contradictory and, in some cases, false concerns raised by these critics of their serotonin review.

No Difference in Antidepressant Effectiveness After Genetic Testing

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Genetic testing may help reduce the length of time people experience the harmful effects of antidepressant drugs, but it is not helpful for predicting efficacy.

Do Not Prescribe Antidepressants for Mild to Moderate Depression or at...

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World Psychiatry article challenges conventional antidepressant prescription practices.

Study Highlights Lack of Evidence for Antidepressants in Treatment of Chronic...

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A new Cochrane review details the lack of evidence for antidepressants in the treatment of chronic pain.

Prescribers Often Fail to Support Patients Discontinuing Antidepressants, Study Finds

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Study reveals most patients are dissatisfied with prescribers' support when discontinuing antidepressants.

Alarming Overprescription Patterns for Older Adults on Antidepressants

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New study finds polypharmacy for 73% of older adults on antidepressants, with 56% at risk of harmful drug interactions.

Global Survey Leads to New Recommendations for Deprescribing Psychiatric Drugs

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Growing rates of long-term psychiatric drug prescriptions and documented issues with withdrawal demonstrate a need for safe deprescribing practices.