Adult

Individuals between the ages of 15 and 24 are more likely to commit a violent crime if they are taking an SSRI antidepressant than if they are not, according to new research out of Sweden. The study published in PLoS Medicine on Tuesday, suggests "warnings about the increased risk of violent behavior among young people taking SSRIs might be needed.”

In a major story, the New York Times presents the re-analysis by David Healy, Jon Jureidini, Mickey Nardo and others of Study 329, published in...

The authors of Study 329 began recruiting adolescents for a comparative study of Paxil, imipramine and placebo in 1994 and finished their investigations in 1997. They dropped a large number of their original cohort, so the randomness element in the study must be open to question. Late in 1998, SmithKline Beecham, the marketers of Paxil, acknowledged in an internal document that the study had shown that Paxil didn’t work for adolescents in terms of the two primary and six secondary outcomes they had established at the start of the study. In a nutshell, Study 329 was negative for efficacy and positive for harm, contrary to their succinct upbeat conclusion.

In 1980, the British Medical Journal published a “Systematic Review of the Benzodiazepines” by the Committee on the Review of Medicines. The committee denied the addictive potential of Benzodiazepines and limited their suggestions to short term use. The results have been devastating.

New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”

I imagine that everybody on this side of the issue knows by now that the eminent psychiatrist Jeffrey Lieberman, MD, Chief Psychiatrist at Columbia, and past President of the APA, called Robert Whitaker "a menace to society." The grounds for Dr. Lieberman's vituperation were that Robert had dared to challenge some of psychiatry's most sacred tenets! But in all the furor, it was largely ignored that in the same interview Dr. Lieberman had said something else that warrants additional discussion.

Probiotics have certainly become quite the rage across the world for the treatment of all kinds of ailments from irritable bowel syndrome (IBS) to infectious diarrhoea to stress to low mood. Some might say that the enthusiasm has been rather slow to develop. Recently, the popular press has propagated the idea that probiotics are the next antidepressants.

New data on the effects of social support after early onset of psychosis suggests that patients with intense social support function better than those without such help, but than once supports are removed the effects diminish.

The Chronicle of Education has called the soaring rates of anxiety and depression among college student an “Epidemic of Anguish.” PBS interviews Jennifer Ruark, the editor of the Chronicle series, and Micky Sharma, the director of counseling at Ohio State University. Ruark reports that about “1 in 4 students reporting to campus counseling centers now are already on some kind of psychotropic medication.” Sharma adds that “just because a student is crying does not mean he or she needs psychotherapy. Sometimes that’s actually the type of emotional response that I would want to see.”

Antipsychotics are currently the predominant treatment for individuals diagnosed with schizophrenia, but there is an accumulating body of research that links the use of these drugs to structural abnormalities in the brain. A recent meta-analysis suggests that gray matter loss in the brain may depend on the dose and class of the antipsychotic.

New York State has investigated five large insurance companies for violating state and federal mental health parity laws by illegally denying to cover claims for behavioral health conditions and drug abuse treatment, according to a report by North County Public Radio (ncpr).

New research finds that brain matter loss in patients diagnosed with schizophrenia is correlated with antipsychotic use, according to Psych Central. The analysis suggests that the continued use of antipsychotics is linked with progressive cortical gray matter loss.

A new study out of the University of Missouri examines the relationship between forgiveness and depression. Medical Daily reports, “while your therapist might tell you to forgive yourself when times get tough, it’s not always just self-forgiveness that decreases depression. Rather, forgiving others seems to have the most positive impact.”

In the September issue of The Journal of the American Medical Association (JAMA) three FDA advisory committee members describe the convergence of factors that made the committee’s recommendation to approve flibanserin especially challenging and politically charged.

In contemporary U.S. culture, people who intentionally hurt their bodies are called “insane.” We may starve ourselves or carve ourselves, taking to the extreme culturally-embedded norms like thinness in an effort to fight against marginalization or cope with internalized shame. But instead of obtaining the voice or place in society we yearn for, we are further ostracized.

In addition to hosting the Panorama programs and The Famous Grouse history of Study 329, Study329.org has a comprehensive timeline on the origins of concerns about the SSRIs and the risk of suicide, initially with Prozac and subsequently with Paxil/Seroxat. The hope is to provide a comprehensive repository for anyone who wants to study SSRIs, RCTs, and Study 329 in particular.

"CNN's Carol Costello explores Operation Tohidu, an experimental rehabilitation program to help veterans with PTSD." Operation Tohidu founder, Dr. Mary Vieten claims PTSD is not a mental illness and "there is no reason to medicate someone who has been traumatized by their war experience." When asked what percentage of soldiers returning with PTSD do not need drugs she responds, "100%."

Parents Opposed to Pot, a group opposed to the legalization of marijuana, criticizes a recent University of Pittsburgh study which found no correlation between pot use and mental health. They contest the results and insist that since the long-term study began in 1987, “skunk” or high THC pot has been on the rise.

Bertha Madras, professor of psychobiology at Harvard Medical School, has printed a critique listing 20 flaws to a recent study finding no differences in physical or mental health problems between users and non-users of marijuana.

On Saturday morning, Susan Inman, writing for HuffPost Canada, published “What You’re not Hearing About the Hearing Voices Movement.” In it, she criticizes HVM for “failing to differentiate between the needs of people who actually have psychotic disorders and those who don't.” On Sunday the Bay Area Hearing Voices Network published an open letter in response, writing: “Ms. Inman has profoundly mischaracterized hearing voices networks (HVNs) and also demonstrates a troubling lack of understanding of the empirical literature on psychosis, optimal psychosocial intervention and recovery.”

The International Business Times covers a new study showing “trials for new antidepressant medications may not be applicable to the population at large.” “The finding, published in the Mayo Clinic Proceedings, shows recent trials are less generalizable than the prior studies, as researchers excluded most depressed patients from drug company-sponsored treatment studies.”

Writing for Truth-Out, hurricane Katrina survivor G. Maris Jones writes: “To adapt to a changing climate, survivors of these catastrophes - especially those in marginalized, low-income communities - need long-term physical and mental health services.” She adds a concurrent call to “assume our responsibility to make positive change through action on climate change.”

Tania Lombrozo for New Hampshire Public Radio (nhpr) asks, “could it be that some people believe psychiatric disorders can be contagious?” A new study in the Journal of Memory & Cognition says “yes,” and adds that this perception influences the way people interact with mental health category members.

What would happen if the mental health system fully recognized the pervasive and profound impacts of trauma on their clients? How might a deeper appreciation of the multi-faceted sequelae of childhood maltreatment and toxic stressors reshape mental health services? While the implementation of trauma-informed care in mental health programs has made significant inroads, the dominant bio-reductionist model continues to constrain and undermine progress.

In this week’s NY Times Modern Love blog Hannah Louise Poston tells the story of living with her severely depressed boyfriend, Joe, and how her decision to buy a kitten improved their relationship. “The next morning when we woke up, the first words out of Joe’s mouth were, ‘Where’s the kitten?’ And the kitten’s first act, when she heard his voice, was to ice-pick her way up the quilt and jump on his face. That same summer, Joe mustered the energy to make major changes in his life…”