Friday, February 26, 2021
antidepressants

Do Antidepressants Work? A People’s Review of the Evidence

After a meta-analysis of RCTs of antidepressants was published in Lancet, psychiatry stated that it proved that "antidepressants" work. However, effectiveness studies of real-world patients reveal the opposite: the medications increase the likelihood that patients will become chronically depressed, and disabled by the disorder.

Withdrawal from Antidepressants

A review of the scientific literature related to withdrawal from antidepressants: mechanism of action; long-term effects of exposure to antidepressants; discontinuation syndromes; relapse upon discontinuation; tapering protocols.

Suicide in the Age of Prozac

During the past twenty years, the American Foundation for Suicide Prevention and American psychiatry have adopted a "medicalized" approach to preventing suicide, claiming that antidepressants are protective against suicide. Yet, the suicide rate in the United States has increased 30% since 2000, a time of rising usage of antidepressants. A review of studies of the effects of mental health treatment and antidepressants on suicide reveals why this medicalized approach has not only failed, but pushed suicide rates higher.

Rigorous Study Finds Antidepressants Worsen Long-Term Outcomes

A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.

Antidepressant Use Leads to Worse Long Term Outcomes, Study Finds

Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.

Study Examines Experience of Long-Term Antidepressant Use

The use of antidepressants has increased substantially in recent years, yet relatively few studies have asked patients about their experiences with these drugs. A...

Antidepressant Use Linked to Dementia

A new study finds that elderly individuals using antidepressants are at significantly higher risk for dementia compared to depressed individuals who did not take the drugs.

New Data Show Lack of Efficacy for Antidepressants

An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.

The Whistleblower and Penn: A Final Accounting of Study 352

After 18 years, the full story of the scientific corruption in a study of paroxetine for bipolar disorder, and the psychiatrist who blew the whistle.

New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”

A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”
veteran suicides

Screening + Drug Treatment = Increase in Veteran Suicides

For the past 15 years, the VA's suicide prevention efforts have focused on getting veterans screened and treated for psychiatric disorders, with antidepressants a first-line therapy. This effort has caused veteran suicide rates to steadily rise.

Over 1,000 Antidepressant Users Describe how Their Personal Life has Been Affected

Survey examines adverse personal and interpersonal effects of antidepressants and the impact of polypharmacy

Anticholinergic Psychiatric Drugs Linked to a 50% Increase in Dementia

People who take anticholinergic drugs, such as antidepressants and antipsychotics, are at a 50% higher risk of dementia.

Researchers: It’s Time to Stop Recommending Antidepressants for Depression

Researchers review a new synthesis of the existing evidence and conclude that the harms of antidepressants outweigh any benefits.
sertraline antidepressant withdrawal

Ambushed by Antidepressant Withdrawal: The Escape Story

I’m alive. More than 30,000 veterans in the past decade alone are not. I was not warned of the risks of this drug. I was not told that once on it, I might never be able to get off it, or the nightmare that would ensue when I tried. I know millions of others were not told either.

Use of Antidepressants Linked to Diabetes

Selective serotonin reuptake inhibitors (such as Prozac and Zoloft) are the most commonly prescribed medication for depression. SSRIs have long been associated with an...

Researchers: “Antidepressants Should Not be Used for Adults with Major Depressive Disorder”

A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.

Psychotherapy Less Effective for People in Poverty and Those on Antidepressants

A new study finds poorer depression and anxiety outcomes in psychotherapy for people in economically deprived neighborhoods and those on antidepressants.

William Styron: His Struggles with Psychiatry and Its Pills

Author William Styron is often remembered for speaking about depression as an illness. But a review of his life reveals that psychiatric drugs may have triggered and even worsened his depressive episodes.

No Matter Which Measure You Use, Antidepressants Aren’t That Effective

Researchers compared the efficacy of antidepressants using different rating scales and found them to be no different—just slightly better than placebo, and not meeting the criteria for clinical significance.
A bottle of pills. Some are spilled out.

Antidepressant Use More Than Doubles Risk of Suicide Attempts

Throughout the past two decades, studies have warned of increased suicide rates in those taking antidepressants, especially in children and adolescents. Researchers also documented...

Antidepressants Blunt Ability to Feel Empathy

A new study suggests that taking antidepressants impairs empathy, while the experience of depression itself does not.

Surviving Antidepressants: An Interview with Adele Framer

That is the truth about withdrawal syndrome: It’s like a 50-50 chance that you’re going to have a problem. If you’re in the unlucky half, you’re gonna be really unlucky.

Prescribing an Epidemic: A Veteran’s Story

Had I known what I know now, I never would have taken any of these drugs, and I absolutely would not have taken a role in which my outreach efforts to get veterans into mental health treatment might place thousands of lives at risk.
one yellow game piece among blue game pieces

Is There a Small Group for Whom Antidepressants Are Effective?

In a new study, researchers found no evidence of antidepressant group variance, which means that there's no particular group of patients who improve more than others on the drug.

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