Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds
Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.
Withdrawal from Antidepressants
A review of the scientific literature related to withdrawal from antidepressants: mechanism of action; long-term effects of exposure to antidepressants; discontinuation syndromes; relapse upon discontinuation; tapering protocols.
SSRI Antidepressants Increase Surgery Risks
There is accumulating evidence that taking SSRI antidepressants increases the risk of bleeding and other complications during surgery, according to a review published in the British Journal of Anaesthesia.
Antidepressants Increase Suicide Attempts in Youth; No Preventative Effect
Researchers find that SSRIs increase suicide attempts up to age 24, and have no preventative effect at any age, even for those at high risk of suicide.
Stuart Shipko – SSRI Withdrawal: Shooting the Odds
We interview Dr. Stuart Shipko, a psychiatrist and author who has a particular interest in the side effects and withdrawal effects of SSRI antidepressants and the need for informed consent when prescribing.
Higher Drop-Out Rates for Those Taking Antidepressants
A review of 73 antidepressant studies finds that 12% more people drop out of clinical trials when taking antidepressants than when taking placebo, evidence that many find the adverse effects of antidepressants difficult to tolerate.
Risk of Bone Fractures With SSRIs Greater Than Thought
Researchers from McMaster University's Department of Medicine, presenting at this year's American Society for Bone and Mineral Research's annual meeting, found that the magnitude...
New Research on Prenatal SSRI Exposure and Autism
Does maternal SSRI exposure increase the chances that a child will develop characteristics associated with Autism Spectrum Disorder (ASD)?
No Good Evidence That Antidepressants Prevent Relapse
Trials of antidepressants for relapse prevention are confounded by withdrawal effects caused by the drugs.
New Data Show Lack of Efficacy for Antidepressants
An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.
Antidepressants Worsen Rapid Cycling in Bipolar Depression
-SSRI antidepressant medications contribute to a significant worsening of emotional "rapid cycling" in patients diagnosed with bipolar disorder.
Does Active Placebo Response Explain Antidepressant Results?
A new study investigated whether participants guessing if they have an antidepressant or placebo affects response rates.
Children Taking ADHD Drugs More Likely to Take Antidepressants as Teens
Adhering to a commonly prescribed medication for ADHD in children is associated with higher chances of being prescribed antidepressants in adolescence.
Summing up the STAR*D Scandal: The Public was Betrayed, Millions were Harmed, and the...
American psychiatry, the NIMH, the larger medical community, and mainstream media have betrayed the American public by failing to make this scandal known.
Study Finds Antidepressants in Pregnancy Increase Risk for Speech Disorders
A new study published this week in JAMA Psychiatry indicates that infants are more likely to develop speech or language disorders if they are exposed to antidepressants during pregnancy.
Listening to the Patient Voice: The Antidepressant Withdrawal Experience
Patient advocates join with researchers and service users to present first-hand experiences of antidepressant withdrawal.
Overuse of Psychiatric Drugs is Worsening Public Mental Health, Doctor Argues
A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.
Discontinuing Psychotropics Reduces Falls in Elderly
Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...
Antidepressants in Pregnancy: Risks to the Fetus and Long-term Health of the Child
The research literature reveals that antidepressant use in pregnancy poses considerable risks to the fetus and the long-term health of the child. These risks include preterm birth, birth defects, abnormal brain development, and behavioral abnormalities in early childhood.
Animal Study Shows Impact of Prozac in Pregnancy on the Child
Researchers found that rats born to mothers given the antidepressant Prozac during pregnancy or breastfeeding exhibited varied behavioral and developmental effects, with implications for the understanding of antidepressant impacts during human pregnancies.
Another Failed Study of âPersonalizedâ Depression Treatment
Due to lackluster antidepressant study results, researchers test if subgroups of depressed patients show greater improvement.
Childhood Trauma Predicts Lack of Response to Antidepressants
Research in Translational Psychiatry finds that childhood maltreatment and trauma predict a greater likelihood of developing chronic depression, and a reduced likelihood of responding to treatment...
Stop Using Antidepressants Except for âthe Most Severe Depression,â Experts Say
Experts advocate limiting antidepressant use to only the most severe cases of depression, emphasizing the need for social and psychological interventions.
The Putative Neurobiology of SSRIs and Aggression
âItâs hapÂpening," said researchers at Northeastern University, "Kids are becoming irriÂtated, aggresÂsive, impulÂsive, agiÂtated, hosÂtile. So you ask the quesÂtion: Why?â They found (through study...
Tapering Strips Help People Stop Using Antidepressants, Study Finds
A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.
