Sunday, July 25, 2021

Antidepressants Cause Autism-Like Gene Expression in Fish

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Prozac, Effexor, and/or carbamazepine induce gene expression patterns in the brains of fathead minnows that mimic those thought to be associated with autism in...

Study Identifies Link Between Antidepressants and Newborn Hypertension

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A new study, published in the American Journal of Physiology, investigates how the use of antidepressants during pregnancy can lead to a life-threatening lung...

Turmeric as Effective as Prozac, With no Side-Effects

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A randomized, controlled study by the Department of Pharmacology of Government Medical College in Bhavnagar, Gujarat, India found that in a study of 60...

Genetic Markers do not Predict Response to Antidepressants

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Researchers from 11 nations in Europe and North America find, in the largest study to date of possible links between genetic markers and antidepressant...

Tapering Strips Help People Stop Using Antidepressants, Study Finds

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A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.

Fluoxetine Not Helpful for Children with Autism

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A clinical trial finds Prozac no better than placebo for improving repetitive behaviors.

Antidepressant Use in Pregnancy Increases Risk of Preterm Birth, Latest Review Finds

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Antidepressant use during pregnancy has been associated with a number of fetal and developmental complications. The latest meta-analysis of the effect of SSRI antidepressants...

Another Failed Study of “Personalized” Depression Treatment

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Due to lackluster antidepressant study results, researchers test if subgroups of depressed patients show greater improvement.
colorful painting of brain

Researchers Fail to Predict Antidepressant Treatment Success

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In a new study published in JAMA Psychiatry, researchers investigated whether they could use EEG (electroencephalograph) technology to predict whether people would feel better...

Pooling Data May Hide Negative Outcomes for Antidepressants

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A new study, published in Psychological Medicine, found evidence for a specific type of publication bias distorting the evidence about antidepressant efficacy.

Rigorous Study Finds Antidepressants Worsen Long-Term Outcomes

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A new study conducted by Jeffrey Vittengl at Truman University has found that taking antidepressant medications resulted in more severe depression symptoms after nine years.

New Algorithms Fail to Predict Antidepressant Treatment Outcomes

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Researchers suggest that because most antidepressant “success” is due to the placebo effect, they may never find a way to predict outcomes.

Major Review Finds Antidepressants Ineffective, Potentially Harmful for Children and Teens

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In a large review study published this week in The Lancet, researchers assessed the effectiveness and potential harms of fourteen different antidepressants for their use in children and adolescents. The negative results, familiar to MIA readers, are now making major headlines.

Suicidal Thoughts and Behavior With Antidepressant Treatment: A Reanalysis

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In 2004 and 2006, the FDA concluded that SSRI antidepressants increased the risk of suicidal ideation in children and adolescents. However, in this month's...

Researchers Ask, ‘Why Do Antidepressants Stop Working?’

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An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.

Researchers: Antidepressant Withdrawal, Not “Discontinuation Syndrome”

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Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.

Antidepressants During Pregnancy Do Not Appear To Reduce Relapses And Hospitalizations

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Continuing to take antidepressants during pregnancy was associated with higher rates of depressive relapses and hospitalizations than discontinuing.

Antidepressants Not Superior to Psychotherapy for Severe Depression

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On Wednesday, JAMA Psychiatry released a meta-analysis comparing the results of cognitive-behavioral therapy and antidepressant medication in severely depressed populations. Currently, many practice guidelines suggest that antidepressants be used over psychotherapy for major depressive disorder. The analysis, however, found that “patients with more severe depression were no more likely to require medications to improve than patients with less severe depression.”

Four Essential Studies on Antidepressant Withdrawal Every Prescriber Must Read

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A researcher and service user Stevie Lewis recounts her own experience with antidepressant withdrawal and what she wishes her doctors knew.

Study Finds SSRIs Associated with Increased Risk for Violent Crime

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Study finds an apparent connection between SSRIs, the most commonly prescribed type of antidepressant, and increased risk of violent crime.

Int’l Task Force Doesn’t Endorse Antidepressants for Bipolar

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Noting a "striking incongruity between the wide use of and the weak evidence base for the efficacy and safety of antidepressant drugs in bipolar,"...

More Than Two-Thirds of Antidepressants Prescribed Against Guidelines

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Results of a new study reveal that sixty-nine percent, or more than two-thirds, of patients prescribed antidepressant drugs have never, in their medical history, met the criteria for major depression. The study, published in the Journal of Clinical Psychiatry this month, also found that several demographic factors, like race and gender, were associated with the prescription of antidepressants.

Antidepressant Use Does Not Prevent Suicide, Study Finds

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A new study has found that antidepressants are ineffective for reducing suicide attempts. Researchers report that the risk of suicide is particularly high in the first month after starting an antidepressant.

Antidepressant Caused Six-fold Artery Plaque Build-up in Monkeys

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Zoloft caused up to six-fold increases in build-up of atherosclerosis plaque in the coronary arteries of monkeys.

Risk of Depressive Relapse Three Times Higher After Previous Antidepressant Use

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A new study found that having been prescribed an antidepressant previously was associated with an increased risk of depressive relapse.

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