Antidepressant Trials “Hijacked for Marketing Purposes,” Researchers Say
About half of the large antidepressant trials are biased enough to be considered “seeding trials,” according to the researchers.
Not Even the Unborn Are Safe from Psychiatric Harm
Medical organizations and the media dismiss the experts and the large body of research telling of fetal harm from exposure to SSRIs during pregnancy.
Listening to the Patient Voice: The Antidepressant Withdrawal Experience
Patient advocates join with researchers and service users to present first-hand experiences of antidepressant withdrawal.
Antidepressants Increase Brain Bleed Risk
A study published in this month’s issue of Stroke found that antidepressants may increase the risk of microbleeds in the brain. Both SSRI and SNRI antidepressants can disrupt natural clotting mechanisms and lead to increased adverse bleeding incidents and prolonged bleeding times.
Fluoxetine in Adolescence Raises Sensitivity to Stress in Adults
Research on neurochemicals associated with moods in mice and rats finds that, while less depression-like behavior was observed in those receiving fluoxetine (Prozac) administration...
Adverse Reactions to Psychiatric Medications Hospitalize 17,000 Annually
Nearly 90,000 American adults are going to emergency rooms every year in response to adverse events from psychiatric medications, according to a study in...
Fava: Antidepressants in Severe Cases, Short Duration Only
Giovanni Fava has published an integrative analysis of the different sources of scientific research into antidepressants in Psychotherapy and Somatics. “The use of antidepressant...
The Effects of Antidepressant Exposure Across Generations: An Interview with Dr. Vance Trudeau
Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.
Antidepressant Withdrawal Symptoms Linked to Life-Altering Consequences, New Study Shows
A new study reveals that withdrawal symptoms from antidepressants can last years, disrupting lives and relationships.
New Data Reveal the Full Extent of STAR*D Failure
The initial study, which has been used to promote antidepressants, employed outcome switching to hide poor results.
FDA Pans Depression Patch For Children and Teens
The FDA released a report in July of a trial on children and adolescents of the selegiline (Emsam) transdermal patch for treatment of depression,...
New Data Show Lack of Efficacy for Antidepressants
An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.
Effects of Psychotropic Drugs on Developing Brains: Protocol
Animal studies have raised concerns about SSRIs and ADHD stimulants inducing lasting abnormalities in the developing brain. Researchers from the University of Amsterdam are...
‘Do Antidepressants Work?’ is the Wrong Question
“This research points to the inadequacy of asking the simple question: ‘Do antidepressants work?’ Instead, the value or otherwise of antidepressants needs to be understood in the context of the diversity of experience and the particular meaning they hold in people’s lives.”
SSRI Antidepressants Appear to Raise Risk of Serious Respiratory Disease in Newborns
A new study has reinforced earlier warnings that taking SSRI antidepressants late in pregnancy appears to put mothers at a slightly increased risk of having newborns with persistent pulmonary hypertension.
New Study Finds Brain Changes in Newborns Exposed to Antidepressants
A fist of its kind neuroscience study, published this month in Cerebral Cortex, found changes in the brain electrical activity of infants exposed to SSRI antidepressants during pregnancy.
New Review: Antidepressants Come with Minimal Benefits, Several Risks
A review of research on antidepressant efficacy finds that an unfavorable risk-to-benefit ratio.
Antidepressant Use Linked to Sexual Dysfunction, Why Aren’t Prescribers Discussing It?
Research sheds light on the impact of antidepressants on sexual dysfunction, emphasizing the need for patient-physician communication.
Antidepressants in Pregnancy: Risks to the Fetus and Long-term Health of the Child
The research literature reveals that antidepressant use in pregnancy poses considerable risks to the fetus and the long-term health of the child. These risks include preterm birth, birth defects, abnormal brain development, and behavioral abnormalities in early childhood.
New Algorithms Fail to Predict Antidepressant Treatment Outcomes
Researchers suggest that because most antidepressant “success” is due to the placebo effect, they may never find a way to predict outcomes.
GSK to Face Class Action over Antidepressants for Children
A Sydney, Australia law firm has launched a class action on behalf of people who as children and adolescents were prescribed Glaxosmithkline's drug Paroxetine. Despite...
Promising Preliminary Results from a Small Study of Psilocybin-Assisted Therapy
A new study offers promising results for psilocybin-assisted psychotherapy for depression.
Antidepressants, Not Depression, Raise Risk of Preeclampsia in Pregnancy
In a study of 69,448 pregnant women with depression, researchers from the Harvard school of public health found that use of SSRI (selective serotonin...
The Putative Neurobiology of SSRIs and Aggression
“It’s happening," said researchers at Northeastern University, "Kids are becoming irritated, aggressive, impulsive, agitated, hostile. So you ask the question: Why?” They found (through study...
Antidepressants Are Not More Effective for Severe Depression, Study Finds
A new study, published in Acta Psychiatrica Scandinavica, found that antidepressant efficacy was not dependent on severity.
