Sunday, July 25, 2021

Stuart Shipko – SSRI Withdrawal: Shooting the Odds

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We interview Dr. Stuart Shipko, a psychiatrist and author who has a particular interest in the side effects and withdrawal effects of SSRI antidepressants and the need for informed consent when prescribing.

Tapering Strips Help People Stop Using Antidepressants, Study Finds

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A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.

Strategies for Tapering and Discontinuing Antidepressants

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A new review of strategies to support both patients and practitioners through the process of discontinuing antidepressants.

Youth Antidepressant Use Associated With Increased Suicide and Self-Harm

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National data on rates of youth antidepressant prescription, suicide, and self-harm in Australia sparks public health debate about drug safety.

Study Finds SSRIs Associated with Increased Risk for Violent Crime

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Study finds an apparent connection between SSRIs, the most commonly prescribed type of antidepressant, and increased risk of violent crime.

JAMA Psychiatry Retracts Antidepressant Study

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Once an appropriate statistical method was used, the study findings were “no longer valid,” according to the editors of JAMA and JAMA Psychiatry.

New Analysis: Antidepressants Still Linked to Suicide

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“This is remarkable for drugs that are used to treat depressive symptoms,” write the researchers.

New Algorithms Fail to Predict Antidepressant Treatment Outcomes

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Researchers suggest that because most antidepressant “success” is due to the placebo effect, they may never find a way to predict outcomes.

No Good Evidence That Antidepressants Prevent Relapse

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Trials of antidepressants for relapse prevention are confounded by withdrawal effects caused by the drugs.

Antidepressant Misinformation Promoted on Popular Websites

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A new study indicates that popular online resources do not accurately present the scientific evidence on the risks and benefits of antidepressants.

Antidepressant Use Continues to Climb Among Youth on Medicaid

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New study finds that Medicaid enrolled youth were 14 times more likely to be on an antidepressant in 2014 than in 1987.

Researchers Find Paroxetine Harms Developing Brain

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Researchers at Johns Hopkins test paroxetine on developing brain cells and discover numerous neurotoxic effects.

Suicide Warning on Antidepressant Label is Justified, Researchers Say

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Researchers confirm that the suicide warning for antidepressants is justified by the evidence and that claims that the warning is harmful lack support.
VA Secretary Robert Wilkie

An Open Letter to VA Secretary Robert Wilkie: A Plan for Deprescribing Veteran Suicides

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Through my research and experiences, I've found that what the Veterans Administration has been doing to fight the veteran suicide epidemic isn't working and appears to be unintentionally exacerbating it. These problems are fixable. But I need your help.

Researchers: Antidepressant Withdrawal, Not “Discontinuation Syndrome”

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Researchers suggest that the pharmaceutical industry had a vested interest in using the term “discontinuation” in order to hide the severity of physical dependence and withdrawal reactions many people experience from antidepressants.
one yellow game piece among blue game pieces

Is There a Small Group for Whom Antidepressants Are Effective?

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In a new study, researchers found no evidence of antidepressant group variance, which means that there's no particular group of patients who improve more than others on the drug.
empty medical waiting room

Higher Drop-Out Rates for Those Taking Antidepressants

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A review of 73 antidepressant studies finds that 12% more people drop out of clinical trials when taking antidepressants than when taking placebo, evidence that many find the adverse effects of antidepressants difficult to tolerate.
colorful painting of brain

Researchers Fail to Predict Antidepressant Treatment Success

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In a new study published in JAMA Psychiatry, researchers investigated whether they could use EEG (electroencephalograph) technology to predict whether people would feel better...

The Whistleblower and Penn: A Final Accounting of Study 352

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After 18 years, the full story of the scientific corruption in a study of paroxetine for bipolar disorder, and the psychiatrist who blew the whistle.

Researchers Set the Record Straight on Controversial Zoloft Study

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An issue of Lancet Psychiatry is devoted to clarifying the lack of efficacy for Zoloft (sertraline).

Prescribing an Epidemic: A Veteran’s Story

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Had I known what I know now, I never would have taken any of these drugs, and I absolutely would not have taken a role in which my outreach efforts to get veterans into mental health treatment might place thousands of lives at risk.

How Antidepressants Shape Young Women’s Sense of Self

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Young women’s narratives indicate ways antidepressants have shaped their sense of self.

No Matter Which Measure You Use, Antidepressants Aren’t That Effective

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Researchers compared the efficacy of antidepressants using different rating scales and found them to be no different—just slightly better than placebo, and not meeting the criteria for clinical significance.

Psychotherapy Less Effective for People in Poverty and Those on Antidepressants

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A new study finds poorer depression and anxiety outcomes in psychotherapy for people in economically deprived neighborhoods and those on antidepressants.

Increased Antidepressant Use Does Not Decrease Depression Prevalence in Older Adults

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The use of antidepressants has risen quickly among older adults but the rate of depressive symptoms in this population has not declined as a result.

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