Antidepressants

Antidepressants were more effective for depressed patients who were more “optimistic.” Still, only 30% responded to SSRIs.

The research literature reveals that antidepressant use in pregnancy poses considerable risks to the fetus and the long-term health of the child. These risks include preterm birth, birth defects, abnormal brain development, and behavioral abnormalities in early childhood.

Those using antidepressants long-term were more likely to experience withdrawal and to have severe withdrawal symptoms.

A new study reveals that withdrawal symptoms from antidepressants can last years, disrupting lives and relationships.

Millions of people are trying multiple antidepressant drugs without success, and psychiatry labels them “treatment resistant.”

New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.

American psychiatry, the NIMH, the larger medical community, and mainstream media have betrayed the American public by failing to make this scandal known.

Combining drugs and therapy also did not lead to better depression outcomes than therapy alone.

The researchers theorized that this increased effectiveness was due not to “antidepressant” properties, but rather to the drug’s side effects, which include insomnia, drowsiness, and nausea.

The studies are of short duration and are riddled with methodological issues like unblinding and failure to assess withdrawal.

A large-scale study reveals that antidepressant use is linked to faster cognitive decline in dementia patients, raising concerns about their widespread prescription.

During the past twenty years, the American Foundation for Suicide Prevention and American psychiatry have adopted a "medicalized" approach to preventing suicide, claiming that antidepressants are protective against suicide. Yet, the suicide rate in the United States has increased 30% since 2000, a time of rising usage of antidepressants. A review of studies of the effects of mental health treatment and antidepressants on suicide reveals why this medicalized approach has not only failed, but pushed suicide rates higher.

After a meta-analysis of RCTs of antidepressants was published in Lancet, psychiatry stated that it proved that "antidepressants" work. However, effectiveness studies of real-world patients reveal the opposite: the medications increase the likelihood that patients will become chronically depressed, and disabled by the disorder.

I’m alive. More than 30,000 veterans in the past decade alone are not. I was not warned of the risks of this drug. I was not told that once on it, I might never be able to get off it, or the nightmare that would ensue when I tried. I know millions of others were not told either.

We interview Dr. Stuart Shipko, a psychiatrist and author who has a particular interest in the side effects and withdrawal effects of SSRI antidepressants and the need for informed consent when prescribing.

An analysis of FDA adverse event reports related to esketamine shows the potential for negative effects such as suicidal and self-injurious ideation.

Researchers: Fetal exposure to vilazodone hampers neurodevelopment and leads to "long-lasting neurodevelopmental impairments."

For the past 15 years, the VA's suicide prevention efforts have focused on getting veterans screened and treated for psychiatric disorders, with antidepressants a first-line therapy. This effort has caused veteran suicide rates to steadily rise.

Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Using genetic analysis, a new study finds that antidepressants—not depression—are responsible for a significant rise in type 2 diabetes risk.

That is the truth about withdrawal syndrome: It’s like a 50-50 chance that you’re going to have a problem. If you’re in the unlucky half, you’re gonna be really unlucky.

Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.

When the CDC released data revealing an increasing suicide rate in the US, some experts, speaking to major media outlets, speculated that the increase...

A new study, published in Molecular Psychiatry, investigates the prevalence and typical characteristics of antidepressant withdrawal syndrome (AWS) through analyzing available research. Researchers found...

A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.