Antipsychotics

Nancy Andreasen talks with the New York Times in 2008 about her MRI findings that antipsychotics cause the brain to shut down and atrophy,...

1978 study of 80 young males diagnosed with acute schizophrenia, finding that "many unmedicated-while-in-hospital patients showed greater long-term improvement, less pathology at follow-up, fewer...

In a review of 681 studies comparing use of antipsychotic medication with placebo, milieu, or psychosocial treatment in first- or second-episode schizophrenia spectrum disorders,...

Taiwanese researchers found that second-generation antipsychotics increased the risk of pneumonia in a sample of 33,024 inpatients. Read more              ...

In a study of 33,024 Taiwanese inpatients, researchers found there was a 3.18 times higher, dose-dependent risk of pneumonia associated with clozapine. Quetiapine, olanzapine,...

May, 2003 article in the New York Times questioning the promise of second-generation antipsychotics. Go to New York Times              ...

An overview of 52 randomized controlled trials of conventional v. atypical antipsychotics in a total of 12,649 patients, published in the British Medical Journal in...

Robert Whitaker's comprehensive 2004 review of the record for antipsychotic outcomes. Go to Psychrights.org                        ...

Joanna Moncrieff's 2006 paper in Medical Hypotheses discusses the possibility that the research on maintenance and discontinuation of medication is flawed because it fails...

Article in the Journal of Psychiatric and Mental Health Nursing Go to "Addressing Non-Adherence to Antipsychotic Medication: A Harm Reduction Approach"          ...

Researchers in the U.K. found that dopamine synthesis among twins with and without diagnoses of schizophrenia was unrelated to diagnosis, suggesting that excess dopamine...

In a study of 53 adolescents at risk for psychosis, researchers from Canada and the U.S. looked at treatment with antidepressants, antipsychotics, and no...

In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...

Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...

In a nine-year study of all 2,224 residents of Leppävirta, Finland who were 65 years old or older, researchers found that the 332 residents...

Researchers at Johns Hopkins, The Mayo Clinic, Harvard Medical School, Duke and others found in a study of 230 Alzheimer's patients tracked over four...

In 211 patients studied for up to 14 years, Nancy Andreason et al. found measurable brain tissue loss associated with antipsychotic use. The results...

Sedation from antipsychotics can be mistaken for negative symptoms as well as increase noncompliance, this study in the African Journal of Psychiatry says, and...

The New York Times reports that a two-year longitudinal study of over 13,000 men and women over 65 found that anticholinergic medications, which include many...

In a study of antipsychotics used to treat 75,445 patients in nursing homes in the United States, researchers from Harvard Medical School, Columbia and...

Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...

Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...

English health minister Paul Burstow is seeking to outlaw the 'silent scandal' of inappropriate antipsychotics for dementia by proposing legislation that imposes up to...

Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

Researchers report in the February issue of Archives of General Psychiatry that cognitive therapy improved both positive and negative symptoms in "low-functioning" patients with...