‚ÄúTreating Parkinson’s Psychosis With Antipsychotics May Boost Death Risk‚ÄĚ

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The Psychiatric Advisor reports on new research from King’s College London that suggests that antipsychotics can cause serious harm to people with Parkinson’s.

The Legal and Moral Issues of Drugging Children

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Jim Gottstein’s presentation March 29, 2012 at the APA’s Humanistic Division. Mr. Gottstein talks about the the legal and moral issues of the massive number...

Schizophrenia’s Tangled Roots

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From Sapiens: Researchers are increasingly recognizing the role that social and environmental factors, including childhood abuse, stressful events, and poverty, play in the development of...

Meta-Analysis Ties Gray Matter Loss to Antipsychotic Dose

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Antipsychotics are currently the predominant treatment for individuals diagnosed with schizophrenia, but there is an accumulating body of research that links the use of these drugs to structural abnormalities in the brain. A recent meta-analysis suggests that gray matter loss in the brain may depend on the dose and class of the antipsychotic.

University of Minnesota Psychiatry: A Pattern of Research Abuse

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KMSP News has aired a report of yet another mentally ill man pressured to enroll in a study of an unapproved antipsychotic drug, with near-disastrous results. His story bears a striking resemblance to the case of Dan Markingson, who committed suicide in a University of Minnesota study in 2004.

Children Diagnosed with ADHD Younger are More Likely to get Multiple Medications

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New research demonstrates that children diagnosed with ADHD at younger ages are more likely than those diagnosed later to receive multiple medications within five years of their diagnosis.

Negative Symptoms Predict Quality of Life

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Researchers assessed 55 first-episode drug-naive people with schizophrenia diagnoses in New Delhi, India for the predictive value of symptoms on quality of life (QOL)....

Not an Onion Study: Underpowered Analysis Of Poor Quality Data Finds Antipsychotics Actually Aren’t...

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University of Groningen researchers analyzed only small, short-term clinical trials of generally poor quality to determine that antipsychotics are not linked to increased risk of death in elderly people with dementia.

J&J Loses Case Over Risperdal Antipsychotic Causing Male Breast Growth

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A jury decided Johnson & Johnson must pay a Philadelphia man $2.5 million in damages "for failing to warn that its Risperdal antipsychotic could cause gynecomastia."

Cognitive Therapy Shown to be Effective For Schizophrenia

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Researchers report in the February issue of Archives of General Psychiatry that cognitive therapy improved both positive and negative symptoms in "low-functioning" patients with...

Sudden Death of a Relative in Early Childhood Increases Risk of Psychotic Disorder

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A team from Ireland, Finland and Sweden found, in a study of all those born in Helsinki in a 30-year period (1960 to 1990)...

2nd-Generation Antipsychotics Cause Extrapyramidal Side Effects as Much as 1st-Generation

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According to researchers from Yale and the U.K., the improvements in extrapyramidal side effects expected from 2nd-generation antipsychotics has not been realized, while the...

Therapy Without Drugs May Ward Off Psychosis

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A double-blind, randomized, placebo-controlled study comparing outcomes from risperidone, cognitive therapy, and supportive therapy in a cohort of 115 at-risk young adults over a...

Seroquel Abuse Rising, Along With Ambulance Calls

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Australian researchers have uncovered an alarming increase of Seroquel-related ambulances calls. Rising prescriptions of of the drug along with its developing use as a drug...

Study Finds Improved Functioning for ‚ÄėSchizophrenia‚Äô Without Antipsychotics

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Long-term treatment with antipsychotic drugs is currently considered the standard treatment for patients diagnosed with ‚Äėschizophrenia.‚Äô A new study challenges this practice, however. The...

The Cure May Be Worse Than the Disease

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Maintenance Antipsychotic Therapy.  Cole, J. American Journal of Psychiatry, 132 (1977): 32-6. In 1977, Jonathan Cole, the former head of the NIMH Psychopharmacology Service Center, concluded that...

J&J Loses $1.75 Million in Risperdal Male Breast Trial; Thousands of Cases Pending

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In the third major verdict of its kind, drug giant Johnson & Johnson was ordered to pay a Maryland man who grew female breasts while taking the antipsychotic Risperdal. The company failed to warn doctors, patients, and regulators of the risk of abnormal breast development in young males and now faces about 5,400 lawsuits involving the drug.

Children on Antipsychotics 50% More Likely to Develop Diabetes

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Antipsychotic drugs increased the risk of children developing diabetes by 50%, and with an antidepressant added, their risk doubled.

“Why People Take Antipsychotics For Depression”

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-Buzzfeed looks at the history -- and present -- of how antipsychotic drugs became a common treatment for depression, despite their apparent lack of effectiveness.

Tapering Off Medications When ‚ÄúSymptoms Have Remitted”: Does That Make Sense?

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While a 2-year outcome study by Wunderink, et al. has been cited as evidence that guided discontinuation of antipsychotics for people whose psychosis has remitted results in twice as much ‚Äúrelapse,‚ÄĚ a not-yet-published followup of that study, extending it to 7 years using a naturalistic followup, finds that the guided discontinuation group had twice the recovery rates, and no greater overall relapse rate (with a trend toward the medication group having more relapse.)

Life for Psychiatrists after Reading Bob Whitaker: Let’s Take Back Substance Abuse Treatment

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An astounding development is the explosion in the numbers of substance abusers being diagnosed with Bipolar. I teach a class in Substance Abuse at...

Slew of New Studies Spot Links Between Psychiatric Medications and Bone Loss, Fractures

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Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

Antipsychotics Triple the Risk of Diabetes in Children and Youth

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Researchers from Vanderbilt and Columbia Universities and the FDA find that, through a retrospective cohort study of 28,858 patients of the Tennessee Medicaid program...

Drug Treatment for Borderline Personality Disorder Not Supported By Evidence

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New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the ‚ÄúAmerican Psychiatric Association‚Äôs practice guidelines endorsement of SSRIs as first-line therapies for BPD,‚ÄĚ the results of the meta-analysis reveal that pharmacotherapy in BPD is ‚Äúnot supported by the current literature,‚ÄĚ and ‚Äúshould be avoided whenever possible.‚ÄĚ

Different Antipsychotics Have Different Effects on Brain Volume

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First generation antipsychotics seem to cause general brain volume loss, while second generation antipsychotics seem to both increase and decrease the thickness of different parts of the brain.