$1 Billion J&J Settlement Rejected as Insufficient
Federal prosecutors have rejected as insufficient the $1 billion settlement reached two months ago between Johnson & Johnson and prosecutors in Philadelphia to resolve...
Shooter in Family Murder/Suicide on High Level of Antipsychotics
Denis Bay had high levels of prescription drugs used to treat schizophrenia and bipolar illness in his blood on February 3, when he shot...
Women on SSRIs Less Likely To Breastfeed
In a prospective cohort study of 466 pregnant women over 10 years, researchers at the California Teratogen Information Service found that women exposed to...
Activity-Based Therapies Reduce Antipsychotic Use
Researchers from the University of North Carolina found that activity-based therapy and care reduced the use of antipsychotics in a study of 107 people...
High Levels of Antipsychotics in Shooter
Denis Bay had high levels of antipsychotics and mood stabilizers in his blood when he shot his wife and two daughters. 911 dispatchers described...
Overprescribing of Benzodiazepines
Norwegian researchers found that 14.6% (27,861) of patients who were prescribed benzodiazepines used two simultaneously, despite the fact that all benzodiazepines have essentially the...
MRI Studies
During the 1990s, researchers using MRI technology discovered that antipsychotics shrink the frontal lobes and cause an enlargement of the basal ganglia. In the...
One Hundred Years of Schizophrenia
One Hundred Years of Schizophrenia. Hegerty, J. American Journal of Psychiatry 151 (1994):1409-1416.
In 1994, Harvard Medical School researchers reported that outcomes for schizophrenia patients in the U.S....
The Vermont Longitudinal Study & Correction of Seven Myths
In a long-term study of schizophrenia patients released during the late 1950s and early 1960s from the back wards of Vermont State Hospital, Courtenay...
The International Pilot Study of Schizophrenia
The International Pilot Study of Schizophrenia. Leff, J.Psychological Medicine, 22 (1992):131-145.
The first World Health Organization study that compared schizophrenia outcomes in "developed" and "developing" countries...
Drug-induced Supersensitivity Pscychosis
In the late 1970s, Canadian investigators identified the biological changes caused by antipsychotics that lead to the high relapse rates. Because the drugs dampen...
The Cure May Be Worse Than the Disease
Maintenance Antipsychotic Therapy. Cole, J. American Journal of Psychiatry, 132 (1977): 32-6.
In 1977, Jonathan Cole, the former head of the NIMH Psychopharmacology Service Center, concluded that...
Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated?
Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated? Rappaport, M. International Pharmacopsychiatry, 13 (1978), 100-111.
In this 1978 study, Maurice Rappaport and his colleagues at...
The Treatment of Acute Schizophrenia Without Drugs
The Treatment of Acute Schizophrenia Without Drugs. Carpenter, W. American Journal of Psychiatry, 134 (1977), 14-20.
In this 1977 NIMH study, 49 schizophrenia patients placed into an experimental...
Comparing five-year outcomes in the pre-Thorazine era and the post-Thorazine era.
Comparison of Two Five-Year Follow-up Studies.Bockoven, J. American Journal of Psychiatry, 132 (1975), 796-801.
In this study, Boston psychiatrists Sanbourne Bockoven and Harry Solomon compared relapse rates...
Discontinuation of Chemotherapy for Chronic Schizophrenics
Discontinuation of Chemotherapy for Chronic Schizophrenics. Prien, R. Hospital and Community Psychiatry, 22 (1971), 20-23.
In this NIMH study, the earlier finding that relapse rates rose in...
Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication
Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication. Prien, R. British Journal of Psychiatry, 115 (1968), 679-86.
The critical finding of this NIMH study was that...
NIMH’s First Follow-Up Study
a) One Year After Discharge. Schooler, N. American Journal of Psychiatry, 123 (1967):986-995.
This NIMH study looked at one-year outcomes for 299 patients who had been treated either...
Brain Volume Recovers With Remission, Not With Medication
In a prospective study of 28 outpatients with major depression, Canadian researchers investigated whether brain volume changes stabilized with antidepressant treatment and/or reversed with...
Ongoing Brain Changes With Antipsychotic Treatment
Nancy Andreasen's 2003 study finding ongoing brain changes in persons with schizophrenia diagnoses, despite antipsychotic drug treatment.
Article → ...
NY Times Interview With Nancy Andreasen
Nancy Andreasen talks with the New York Times in 2008 about her MRI findings that antipsychotics cause the brain to shut down and atrophy,...
Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated?
1978 study of 80 young males diagnosed with acute schizophrenia, finding that "many unmedicated-while-in-hospital patients showed greater long-term improvement, less pathology at follow-up, fewer...
No Evidence for Antipsychotics’ Efficacy
In a review of 681 studies comparing use of antipsychotic medication with placebo, milieu, or psychosocial treatment in first- or second-episode schizophrenia spectrum disorders,...
Second-Generation Antipsychotics Increase Risk of Pneumonia
Taiwanese researchers found that second-generation antipsychotics increased the risk of pneumonia in a sample of 33,024 inpatients.
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