Research News

Summaries of research findings that tell of a scientific need to "rethink psychiatry."

Antidepressants, Not Depression, Raise Risk of Preeclampsia in Pregnancy

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In a study of 69,448 pregnant women with depression, researchers from the Harvard school of public health found that use of SSRI (selective serotonin...

Auditory Hallucinations – Expectation, Interpretation, and Emotion

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Researchers in Australia, the U.K., the Netherlands, Canada and Belgium reviewed research on auditory hallucinations (AH) in schizophrenia as well other clinical and nonclinical...

FDA Adds Warnings to Celexa’s Label

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Following up on last August's warning that high doses of Celexa can cause potentially fatal heart rhythm abnormalities, the FDA has added clarification to...

J&J Tries, Fails to Squeeze Whistle Blower in Texas Risperdal Case

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In giving final approval to the $158 million settlement with Texas over illegal promotion of Risperdal, Judge John Dietz denied Johnson &Johnson's request to...

Arkansas Alleges Risperdal Causes Deaths in the Elderly and Lactation in Young Boys

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In opening statements in its lawsuit against Johnson & Johnson for lying about Risperdal's risks and promoting its use for unapproved treatments, Arkansas' lawyer...

Second-Generation Antipsychotics Just as Likely as Older Drugs to Cause EPS

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In a study of an earlier randomized controlled trial of antipsychotics, researchers from Yale and the U.K found that second-generation antipsychotics were as likely...

AztraZeneca Struggling as Generic Seroquel Gets the Green Light

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With a U.S. judge refusing to grant an injunction against generic versions of it's top-selling drug Seroquel last Friday, the Wall Street Journal reports...

Psychiatric Drugs, Especially Antipsychotics, Contribute to Increasing Drug Costs

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Antipsychotics have overtaken antidepressants as the most costly class of psychiatric medication in England, according to a study by Stephen Ilyas and Joanna Moncrieff...

Arkansas’ $1.25 Billion Risperdal Trial Starts Today

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Arkansas' lawsuit against Johnson & Johnson for false and misleading claims regarding Risperdal is set to begin today, the fourth time J&J has a...

Pharmas Exiting Antidepressant Market

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As patents expire on current antidepressants pharmaceutical companies are getting out of the market, according to an article in yesterday's Vancouver Sun. In the latest...

Rejecting Illness as Chronic Contributes to Better Outcomes

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Swiss researchers investigated the paradox that both low and high levels of "insight" are a risk factor for poor outcomes such as depression, hopelessness,...

Hypertension in Pregnancy 50% More Likely With SSRIs

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Researchers in Montreal found in a sample of 1,216 pregnant women that those who used antidepressants were at least 50% more likely to experience...

Recovery-Oriented Services Benefit Providers As Well

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In a study of 114 case managers in Ohio, researchers from Bowling Green State University found that those working at a recovery-oriented center reported...

Living Alone Nearly Doubles Antidepressant Use

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Finnish researchers found that in a study of 3471 men and women, those living alone were almost twice as likely to use an antidepressant....

Pharmaceutical Trial Database Mysteriously Disappears

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The Public Library of Science (PLoS) revealed today that the lead author of a study identifying publication bias (released this week in PLoS Medicine) has...

Publication Bias in Antipsychotic Trials

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Researchers in Oregon looked for discrepancies between published and unpublished FDA-registered trials. They found that four of the 24 FDA-registered trials of second-generation antipsychotics identified...

Mindfulness Decreases Depression & Anxiety, Increases Hope

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In a sample of 56 participants who met criteria for a mood disorder, anxiety disorder, and/or substance dependence, researcher from the Emory School of...

Spontaneous Improvement in Depression, With and Without Placebo

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Researchers at Columbia University and Queens College reviewed 10 trials of antidepressants that used wait-listed controls in order to determine the contribution of spontaneous...

Contribution of Antipsychotics to Suicidality and Depression

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Peter Lehmann reviews the contribution of antipsychotics to suicide and depression in schizophrenia in the current International Journal of Psychotherapy.  Publications about the intrinsic effects of...

Seroquel Abuse Rising, Along With Ambulance Calls

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Australian researchers have uncovered an alarming increase of Seroquel-related ambulances calls. Rising prescriptions of of the drug along with its developing use as a drug...

International Society Removes “Schizophrenia” From Its Name

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Calling "schizophrenia" an unscientific and stigmatizing construct - with little or no reliability or validity - that implies people with the diagnosis have an irreversible brain...

High Cost to Medicaid Programs For Off-Label Use of Antipsychotics

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A study of 42 state Medicaid programs found that 58% of prescriptions for antipsychotics  were not for schizophrenia or bipolar disorder. Off-label prescribing was most prevalent...

Mother Sues Pfizer for Alleged Zoloft-Related Birth Defects

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The latest in a series of Zoloft-related birth defect lawsuits was filed in St. Louis yesterday, by a firm that claims to represent hundreds...

Millionaire Psychiatrist Accused of Deliberate Misdiagnosis for Gain

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Multimillionaire U.K. psychiatrist Dr. George Hibbert is being investigated - potentially by Parliament - for deliberately misdiagnosing hundreds of parents with 'personality disorders' in order to...

45% of Children and Adolescent Inpatients Prescribed Antipsychotics

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In a rare long-term study of antipsychotics used in children and adolescent inpatients, the Institute of Living in Hartford, CT followed 3,851 consecutive admissions...