Research News

Summaries of research findings that tell of a scientific need to "rethink psychiatry."

European Regulators Urge Open Drug Trial Data for All

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In a paper published in PLoS Medicine, representatives of regulatory agencies in the U.K., France, and the Netherlands argue that clinical trial data should...

J&J to Pay $2.2 Billion to Settle Government’s Risperdal Probe

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Johnson & Johnson has agreed to pay $2.2 billion to settle probes by the U.S. government of its marketing of Risperdal and other medications,...

Mountain Hiking Improves Hopelessness, Depression, and Suicidal Ideation in High-Level Suicide Risk

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Researchers in Salzburg, Austria found that 20 participants who had attempted suicide at least once showed a significant reduction in hopelessness (P < 0.0001),...

More Support Sought When Others Attribute Depression to Biology

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In a study of 86 individuals experiencing at least mild depressive symptoms, a person's willingness to seek support from a friend was not related...

PLoS Medicine Series: Global Studies of “Practice-Based Evidence”

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The Public Library of Science calls for "case studies that can help broaden our understanding of global mental health in 'real-life' contexts." The series...

Little Evidence on Effectiveness or Risks of Antipsychotics in Young People

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Evidence-Based Mental Health reviews studies (from 1987 to 2011) of antipsychotics in people under 24 years old, finding weak evidence on comparative effectiveness of antipsychotics or...

Military Court Hears Arguments Re: Chantix-Related Murder Defense

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Judges on the U.S. Court of Appeals for the Armed Forces heard arguments on Tuesday for the defense of former Army paratrooper George D.B....

Family Economic Context Linked to Adolescents’ Antipsychotic Use

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In a study of the Swedish Medical Birth Registry published in the British Medical Journal, researchers identified all 324,510 single children born between 1988...

Janssen to Pay $11M for Failure to Warn of Topamax Birth Defects

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A Philadelphia jury yesterday ordered Johnson & Johnson subsidiary Janssen to pay $11 million to the parents of a five-year-old boy for failure to warn...

Hearing Voices Researched at Edinburgh Book Festival

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Researchers from Durham University's Hearing the Voice project are attending the Edinburgh International Book Festival through August as part of a study, asking both...

Antipsychotics are Poor Sleep Aids

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Research from Australia shows that "remained pervasive" in 70% of a sample of 83 patients medicated with antipsychotics and other medications, and concludes that...

SSRIs Can Harm Babies Prior to Conception

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In addition to the increased risk of respiratory and heart troubles known to accompany SSRI use during pregnancy, SSRIs have been linked to an...

Antidepressants, Not Depression, Raise Risk of Preeclampsia in Pregnancy

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In a study of 69,448 pregnant women with depression, researchers from the Harvard school of public health found that use of SSRI (selective serotonin...

South Dakota Court Revives Cymbalta Suicide Case

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A federal appeals court has reversed a lower court's summary judgment in favor of Eli Lilly,   allowing the parents of a South Dakota...

A Review of Drug-Company Funded Mental Health Websites

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A meta-analysis of studies of mental health websites by John Read found that 42% are either drug company owned or receive funding from drug...

1 in 4 Adults With a Mental Illness Has Been A Victim of Violence...

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In a meta-analysis funded by the World Health Organization and published in The Lancet, studies of 21,500 disabled individuals from Australia, Canada, New Zealand,...

Scant Evidence for Combining Antipsychotics

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Researchers in Barcelona, Spain retrospectively reviewed the use of antipsychotics in 117,811 patients, of whom 9,855 were given combinations of antipsychotics and 13,763 were...

Antidepressant is Toxic to Fungus

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Zoloft isn't just for depression any more; it also kills fungal meningitis. Researchers from Texas A&M find that "The problem for many current antifungal...

Physical Inactivity Associated with Worse Cognitive Functioning in Psychosis

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Higher levels of sedentary behavior are associated with poorer cognitive functioning in patients diagnosed with schizophrenia.

Symptoms do not Correlate with Quality of Life in Schizophrenia

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Researchers in France found that among 306 outpatients followed for a year, quality of life remained stable relative to subjects' expectations and perceptions about...

“The Disease Entity in Psychiatry: Fact or Fiction?”

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In the context of the debate concerning revisions of the DSM and ICD, an article in Epidemiology and Psychiatric Sciences offers "an overview of...

Dissociative Experiences Mediate Childhood Trauma/Auditory Hallucinations

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Researchers in Spain assessed 71 patients diagnosed with psychoses for dissociative experiences, trauma, delusions and hallucinations. Childhood trauma was positively associated with dissociation (r =...

Pharmas Exiting Antidepressant Market

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As patents expire on current antidepressants pharmaceutical companies are getting out of the market, according to an article in yesterday's Vancouver Sun. In the latest...

Glucose Metabolism “Derangements” from Second Generation Antipsychotics Clarified

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New Zealand and Chinese investigators believe they have clarified the mechanisms by which second generation antipsychotics cause serious "derangements" in glucose metabolism in the...

Injuries and Mental Illness

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A retrospective study of 6,234 Medicaid recipients in Maryland by researchers at Johns Hopkins and published online June 2, 2012 by the journal Injury...