scientific freedom

Why We’re Establishing an Institute for Scientific Freedom

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Scientific freedom and integrity are constantly under attack, particularly in healthcare, which is dominated by the drug industry and other economic interests. To help preserve honesty and integrity in science, the new Institute for Scientific Freedom will open on March 9 with an international meeting in Copenhagen.

Investigation Reveals Alarming ECT Practices in England

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Audit of ECT usage, demographics, and adherence to guidelines and legislation raises concern over its continued use.

In Opioid Battle, Cherokee Want Their Day in Tribal Court

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From The New York Times: The opioid epidemic is wreaking havoc on Cherokee families and putting Cherokee children at risk. Now, the Cherokee Nation has...

Study Finds Long-Term Opioid Use Increases Depression Risk

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A study published this week in the Annals of Family Medicine reveals that opioid painkillers, when used long-term, can lead to the onset of depression. The researchers found that the link was independent of the contribution of pain to depression.

Hospitals Need to Earn Their Tax-Exempt Status

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From STAT: Many of the country's most profitable and prominent hospitals enjoy tax-exempt status even though they often fail to meet the health needs of...

Researchers Test Harms and Benefits of Long Term Antipsychotic Use

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Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

Are Psychiatric Experiments on Primates Ethical — Or Even Truly Useful?

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Pediatric psychiatrist Sujartha Ramakrishna describes a planned University of Wisconsin psychiatric experiment "to discover new therapies by dissecting and analyzing the brains of baby...

Prominent Psychiatrists Discuss “the Crisis of Confidence in Medical Research”

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-A large excerpt from a post by David Healy is sandwiched between commentary by psychiatrist Allen Frances.

“Was Sexism Really Responsible for the FDA’s Hesitancy to Sign Off on Flibanserin?”

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“The Food and Drug Administration’s approval of pharmaceutical treatment for low sexual desire in women has launched a heated debate over the dangers and benefits of medicalizing sex,” Maya Dusenbery writes in the Pacific Standard. Is “female Viagra” a feminist victory or a product of clever faux-feminist marketing by Big Pharma?

Outcome Reporting Bias in Antipsychotic Medication Trials

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A new study in the journal Translational Psychiatry, an influential journal in biological psychiatry published by Nature, challenges the state of the research on antipsychotic drugs.

Danish Study Finds Better 10-year Outcomes in Patients Off Antipsychotics

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Study finds that 74% of patients with a psychotic disorder off antipsychotics at end of 10 years are in remission.

New Study Concludes that Antidepressants are “Largely Ineffective and Potentially Harmful”

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A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”

Good Psychologist, Bad Psychologist

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In this episode on BBC Radio, psychiatrist Raj Persaud reports on the CIA's so-called "enhanced interrogation" program, which has frequently been characterized as torture. He discusses...

Big Pharma Might Be Intentionally Confusing You

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From Benzinga: The FDA has suggested that drug commercials may intentionally list potential side effects in such a rapid-fire, overwhelming way that the warning messages...

New Medications Fail to Show Efficacy for Alzheimer’s Disease

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Three phase III clinical trials assessing the efficacy of Lundbeck’s investigational drug idalopirdine for Alzheimer’s disease have failed

Antipsychotics Prescribed Off-Label for Challenging Behaviors

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Antipsychotics are being prescribed to people who may have challenging behaviors but no mental disorder, according to new research published in this month’s issue of BMJ. “Excessive use of psychotropic drugs has individual and systemic implications,” the researchers write. “Antipsychotics, in particular, are associated with several adverse side effects that can impair quality of life and lead to deleterious health outcomes.”

SSRI Ineffective at Treating Depression in Individuals with Chronic Kidney Disease

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Dr. Madhukar Trivedi and colleagues find that the SSRI sertraline does not reduce depressive symptoms any more than placebo in people with Chronic Kidney Disease.

Screening Instruments Do Not Reflect Individual Experiences of Depression

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Researchers detect discrepancies between the language used to describe lived experiences of mental health and the language used in modern screening tools.

Researchers Question Add-On Treatment for ‘Schizophrenia’

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A common practice when antipsychotics are found to be ineffective for schizophrenia is to prescribe a second, additional psychoactive medication. Now, a new study suggests that this practice is not supported by the research.

Massive Reforms for Pharmaceutical System Proposed

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The US/Canadian Pharmaceutical Policy Reform Working Group proposes universal drug coverage and ambitious reforms to the pharmaceutical system.

The Genetics of Schizophrenia: A Left Brain Theory about a Right Brain Deficit in...

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In recent months, two teams of researchers in the UK and the US published complementary findings about the epigenetic origins of schizophrenia that have scientific communities who indulge in ‘genetic conspiracy theories’ abuzz. While these results are intriguing, and no doubt involve pathbreaking research methodologies, this line of thought represents a decontextualized understanding both of the symptoms that are typically associated with schizophrenia, and their causes.

Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds

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Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.

New Study Raises Doubts About fMRI Neuroimaging Research

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More than forty thousand papers have been published using functional magnetic resonance imaging (fMRI) technology to explore the brain. A new analysis of the common...

Positive Antidepressant Study “Misleading” and “Erroneous”

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An analysis of last year’s positive finding in The Lancet about antidepressant efficacy shows errors, obfuscations, and misrepresentations.

Patient Advocacy Groups Take In Millions From Drugmakers

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Kaiser Health News has launched a new database called Pre$scription for Power, which exposes donations pharmaceutical companies have made to patient advocacy groups. The...