Tag: biomarkers
Go/No-Go—How Mental Health Research Took a Wrong Turn: An Interview with...
Marianne Apostolides discusses how Go/No-Go grew from her search for new eating-disorder treatments into a critique of the metaphors, experiments, and technologies shaping contemporary neuroscience and psychiatry. She argues that efforts to reduce distress to circuits, algorithms, and biomarkers often overlook subjectivity, agency, and the human relationships that meaningful care requires.
Radical Changes Could be Coming to ‘Psychiatry’s Bible’
From CNN. "The American Psychiatric Association announced Wednesday that it is radically reconceptualizing the main manual that clinicians use to make a mental health...
A Neuroscientist Evaluates the Standard Biological Model of Depression
Current evidence does not support a biological hypothesis of depression. It is far better predicted by levels of childhood trauma, life stress, and lack of social supports.
It is Time to Abandon the Candidate-Gene Approach to Depression
The candidate-gene approach to depression goes unsupported and is likely based on bad science, new research finds.
Philosophers Challenge Psychiatry and its Search for Mechanisms of Disorder
Attempting to locate the mechanisms of psychiatric disorder is a step in the wrong direction and fails to challenge potentially unjust social practices.
Large Rigorous Study Debunks Popular Gene-Environment Theory of Depression
A large and rigorous meta-analysis fails to find support for the gene-environment interaction theory of depression.
Bipolar Diagnosis Linked to Childhood Adversity
With the ties between traumatic childhood experiences and mental health issues, should we continue to focus on biological approaches?
The Failed Quest for Biomarkers in Psychiatry
A recent commentary by Ganesan Venkatasubramanian and Matcheri Keshavan notes that efforts to identify biomarkers in people diagnosed with psychiatric disorders have been overwhelmingly...
Dr. Nardo on the Curse of Insel’s Legacy
In his reaction to Dr. Makari’s Opinion piece in the ‘Times, entitled Psychiatry’s Mind-Brain Problem, Dr. Nardo articulates why the legacy of NIMH director Thomas Insel is so dangerous. “He may have kept the researchers from spinning off and following some idiosyncratic path, but he did it by forcing them to follow his own idiosyncratic path.”
ADHD: A Destructive and Disempowering Label; Not an Illness
In recent years, we've seen an increasing number of articles and papers from psychiatrists in which they seem to be accepting at least some of the antipsychiatry criticisms, and appear interested in reforms. It is tempting to see this development as an indication of progress, but as in many aspects of life, things aren't always what they seem.














